Protein Alignment CG7741 and CWF19L1

DIOPT Version :9

• Sequence 1: NP_610670.2
• Gene: CG7741 / 36208
• FlyBaseID: FBgn0033615
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_060764.3
• Gene: CWF19L1 / 55280
• HGNCID: 25613
• Length: 538
• Species: Homo sapiens
• Alignment Length: 546
• Identity: 212/546 - (38%)
• Similarity: 310/546 - (56%)
• Gaps: 42/546 - (7%)

  Fly    27 KILVVGDVRGRFKQLFQRVEQVNKKAGPFEILCCVGDFFG--EDKQNEELIAYKNGFKHITVPTY 89
            ::|..|||.|:|..||.||:.:.||:|.|::|.|||:|||  :|.:.||   ||.|.|...:.||
Human     7 RLLACGDVEGKFDILFNRVQAIQKKSGNFDLLLCVGNFFGSTQDAEWEE---YKTGIKKAPIQTY 68

  Fly    90 ILGPNQREHEKYFENLTDGEICTNLTYLGRRGVYTLSSGVKIAYLSGLEAQGTADSAGSEHEFTK 154
            :||.|.:|..|||::....|:..|:|||||:|::|.|||::|.||||.|   :.:.....:.|:.
Human    69 VLGANNQETVKYFQDADGCELAENITYLGRKGIFTGSSGLQIVYLSGTE---SLNEPVPGYSFSP 130

  Fly   155 ADVIAVRNSCLVSKNCST-EYRGVDVLLTSQWP-----FGMQEKENAT---ASKLVSFLCREIKP 210
            .||.::|...     |:| :::|||:||||.||     ||....|..|   .|.|||.|...:||
Human   131 KDVSSLRMML-----CTTSQFKGVDILLTSPWPKCVGNFGNSSGEVDTKKCGSALVSSLATGLKP 190

  Fly   211 RYHFCAINGTHYESAPFR--MPKDETTQFELCTRFISLAEVGNAEKAKYIYALSLKPVDKSRLLD 273
            ||||.|:..|:||..|:|  :...|..|.  .||||:||.|||.||.||:||.|:.|:......:
Human   191 RYHFAALEKTYYERLPYRNHIILQENAQH--ATRFIALANVGNPEKKKYLYAFSIVPMKLMDAAE 253

  Fly   274 LAQKTTNEIPCPFIGLDLGGAIGK------NDSSENRQYFYDMD--GGRRKRQGGDNNK---RDK 327
            |.::..:....|:.......:|||      .:|:  .|:|:|::  .||::...|.::|   ..|
Human   254 LVKQPPDVTENPYRKSGQEASIGKQILAPVEESA--CQFFFDLNEKQGRKRSSTGRDSKSSPHPK 316

  Fly   328 RPRIPQIEQDKCWFCLSSPDVEKHLIITVGEHFYLALAKGPINKHHVMILSTKHVPCAAQLSPDD 392
            :||.|......|||||:||:|||||::.:|.|.|||||||.::..||:||...|.....:||.:.
Human   317 QPRKPPQPPGPCWFCLASPEVEKHLVVNIGTHCYLALAKGGLSDDHVLILPIGHYQSVVELSAEV 381

  Fly   393 WKELNKFKAALRKFFKTLGQVVCFTERHYKSVHLQINALAFEEGYAW--KIKHSFEDKAEEFNLE 455
            .:|:.|:||.||:|||:.|:.....||:|||.|||:..:......:.  .||.:|..:|:|..:|
Human   382 VEEVEKYKATLRRFFKSRGKWCVVFERNYKSHHLQLQVIPVPISCSTTDDIKDAFITQAQEQQIE 446

  Fly   456 FETLPALDSEKMLPEMG-PYFLAELPDDSTLITRQMKHFPIHFARDVFCSENLLNCDEKVNWKDC 519
            ...:|.....|.:.:.| .||..||.....|..|..|:||:.|.|:|..||.:||..:|.:|:.|
Human   447 LLEIPEHSDIKQIAQPGAAYFYVELDTGEKLFHRIKKNFPLQFGREVLASEAILNVPDKSDWRQC 511

  Fly   520 LLDKDEEVAYVEDFRKAFAPFDFTDD 545
            .:.|::|......|||.|.|:|||.|
Human   512 QISKEDEETLARRFRKDFEPYDFTLD 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7741	NP_610670.2	MPP_CWF19_N	29..249	CDD:277326	99/232 (43%)
		HIT_like	320..428	CDD:294158	51/110 (46%)
		CwfJ_C_2	466..543	CDD:282523	29/77 (38%)
CWF19L1	NP_060764.3	MPP_CWF19_N	9..229	CDD:277326	99/232 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	298..324		8/25 (32%)
		HIT_like	328..423	CDD:294158	46/94 (49%)
		CwfJ_C_2	447..535	CDD:282523	30/87 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158275
Domainoid	1	1.000	196	1.000	Domainoid score	I3129
eggNOG	1	0.900	-	-		E1_KOG2476
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41244
Inparanoid	1	1.050	353	1.000	Inparanoid score	I2261
Isobase	1	0.950	-	0	Normalized mean entropy	S2397
OMA	1	1.010	-	-		QHG55395
OrthoDB	1	1.010	-	-		D199603at33208
OrthoFinder	1	1.000	-	-		FOG0004146
OrthoInspector	1	1.000	-	-		oto91822
orthoMCL	1	0.900	-	-		OOG6_103314
Panther	1	1.100	-	-	LDO	PTHR12072
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R771
SonicParanoid	1	1.000	-	-		X2899
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	17	16.750