DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dare and GLT1

DIOPT Version :9

Sequence 1:	NP_477150.1	Gene:	dare / 36203	FlyBaseID:	FBgn0015582	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_010110.1	Gene:	GLT1 / 851383	SGDID:	S000002330	Length:	2145	Species:	Saccharomyces cerevisiae

Alignment Length:	438	Identity:	89/438 - (20%)
Similarity:	157/438 - (35%)	Gaps:	123/438 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 NIFRRGLHTSSARLQVIQSTTPTKR----ICIVGAGPAGFYAAQLILKQLDNCVVDVVEKLPVPF 67
            |.|:.|.         |:...|:.|    :.::|:||||...|.::.:.  ...|.|.|:.....
Yeast  1765 NAFKEGW---------IKPCPPSTRTGFTVGVIGSGPAGLACADMLNRA--GHTVTVYERSDRCG 1818

  Fly    68 GLVRFGVAPDHPEVKNVINTFTKTAEHPRLRYFGNISLGTDVSLRELRDRYHAVLLTYGADQDRQ 132
            ||:.:|: |:....|.::...........:.:..|..:|..:|:.||:::::||:...|:...|.
Yeast  1819 GLLMYGI-PNMKLDKAIVQRRIDLLSAEGIDFVTNTEIGKTISMDELKNKHNAVVYAIGSTIPRD 1882

  Fly   133 LELENEQLDNVISARKFV-----AWYNGLPGAENLAPDLSGRDVTIVGQGNVAVDVARMLLSPLD 192
            |.::..:|.|:..|.:.:     |..|  ...|.:...:.|:.|.:||.|:...|..
Yeast  1883 LPIKGRELKNIDFAMQLLESNTKALLN--KDLEIIREKIQGKKVIVVGGGDTGNDCL-------- 1937

  Fly   193 ALKTTDTTEYALEALSCSQVERVHLVGRRGPLQAAFTIKELREMLKLPNV----DTRWRTEDFSG 253
               .|.....|...|:.                         |:|..|.|    |..|.
Yeast  1938 ---GTSVRHGAASVLNF-------------------------ELLPEPPVERAKDNPWP------ 1968

  Fly   254 IDMQLDKLQRPRKRLTELMLKSLKEQ-GRISG-----SKQFLPIFLRAPKAIAPGEMEFSVTELQ 312
                    |.||....:.....:||. ||...     ||:|:            |..|..||.::
Yeast  1969 --------QWPRVMRVDYGHAEVKEHYGRDPREYCILSKEFI------------GNDEGEVTAIR 2013

  Fly   313 --------------QEAAVPTSSTERLPSHLILRSIGYKSSCVDTGINFD---TRRGRVHNINGR 360
                          |...:| :|.|...:.:||.|:|:....:..|.:.:   ||||.:..:
Yeast  2014 TVRVEWKKSQSGVWQMVEIP-NSEEIFEADIILLSMGFVGPELINGNDNEVKKTRRGTIATL--- 2074

  Fly   361 ILKDDATGEVDPG-LYVAGWLGTGPTGVIVTTMNG---AFAVAKTICD 404
               ||::..:|.| .:..|....|.:.::.....|   |.:|.|.:.|
Yeast  2075 ---DDSSYSIDGGKTFACGDCRRGQSLIVWAIQEGRKCAASVDKFLMD 2119

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dare	NP_477150.1	PLN02852	10..465	CDD:215457	87/435 (20%)
dare	NP_477150.1	NAD_binding_8	34..98	CDD:290186	14/63 (22%)
GLT1	NP_010110.1	gltB	41..1547	CDD:236968
GLT1	NP_010110.1	GOGAT_sm_gam	1640..2125	CDD:162300	89/438 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.820802	Normalized mean entropy	S1767
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.860