DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dare and Fdxr

DIOPT Version :9

Sequence 1:	NP_477150.1	Gene:	dare / 36203	FlyBaseID:	FBgn0015582	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_077067.1	Gene:	Fdxr / 79122	RGDID:	621648	Length:	494	Species:	Rattus norvegicus

Alignment Length:	467	Identity:	219/467 - (46%)
Similarity:	291/467 - (62%)	Gaps:	35/467 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 QSTTPTKRICIVGAGPAGFYAAQLILKQLDNCVVDVVEKLPVPFGLVRFGVAPDHPEVKNVINTF 88
            |.|||  :||:||:||||||.||.:||......||:.||..||||||||||||||||||||||||
  Rat    37 QETTP--QICVVGSGPAGFYTAQHLLKHHTRAHVDIYEKQLVPFGLVRFGVAPDHPEVKNVINTF 99

  Fly    89 TKTAEHPRLRYFGNISLGTDVSLRELRDRYHAVLLTYGADQDRQLELENEQLDNVISARKFVAWY 153
            |:||...|..:.||:.:|.|||:.|||:.||||:|:|||:..:.||:..|:|..|:|||.||.||
  Rat   100 TQTARSDRCAFRGNVVVGRDVSVPELREAYHAVVLSYGAEDHQPLEIPGEELPGVVSARAFVGWY 164

  Fly   154 NGLPGAENLAPDLSGRDVTIVGQGNVAVDVARMLLSPLDALKTTDTTEYALEALSCSQVERVHLV 218
            ||||..:.||||||.....|:||||||:||||:||:|.:.|:.||.||.||..|..|:|:.|.:|
  Rat   165 NGLPENQKLAPDLSCDTAVILGQGNVALDVARILLTPPEHLEKTDITEVALGVLRQSRVKTVWIV 229

  Fly   219 GRRGPLQAAFTIKELREMLKLPNVDTRWRTEDFSGIDMQLDKLQRPRKRLTELMLKSLKEQ---- 279
            |||||||.||||||||||::||.........||.|:..::..:.|||||||||:|::..|:
  Rat   230 GRRGPLQVAFTIKELREMIQLPGTQPILDPSDFLGLQDRIKDVPRPRKRLTELLLRTATEKPGVE 294

  Fly   280 ---GRISGSKQFLPIFLRAPKAIAP-------GEMEFSVTEL----QQEAAVPTSSTERLPSHLI 330
               .|...|:.:...|.|:|:.:.|       ..:..:||.|    :...||||...|.||..|:
  Rat   295 EAARRALASRAWGLRFFRSPQQVLPTPDGRRVAGIRLAVTRLEGVGESTRAVPTGDVEDLPCGLL 359

  Fly   331 LRSIGYKSSCVDTGINFDTRRGRVHNINGRILKDDATGEVDPGLYVAGWLGTGPTGVIVTTMNGA 395
            |.|:||||..:|..:.||.:.|.:.|..||::.       .||||.:||:..||||||.|||..:
  Rat   360 LSSVGYKSRPIDPSVPFDPKLGIIPNTEGRVVN-------APGLYCSGWVKRGPTGVITTTMTDS 417

  Fly   396 FAVAKTICDDINTNALDTSSVKPGYDA-------DGKRVVTWDGWQRINDFESAAGKAKGKPREK 453
            |..::.:..|:....| .|..:|||.|       .|.|.|::..|::::..|.|.|:..||||||
  Rat   418 FLTSQVLLKDLKAGLL-PSGPRPGYTAIQALLSDRGVRPVSFSDWEKLDAEEVARGQGTGKPREK 481

  Fly   454 IVSIEEMLRVAG 465
            :|...|||::.|
  Rat   482 LVDRREMLQLLG 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dare	NP_477150.1	PLN02852	10..465	CDD:215457	218/465 (47%)
dare	NP_477150.1	NAD_binding_8	34..98	CDD:290186	44/63 (70%)
Fdxr	NP_077067.1	PLN02852	20..489	CDD:215457	216/461 (47%)
Fdxr	NP_077067.1	NAD_binding_8	45..>90	CDD:290186	29/44 (66%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	192	1.000	Domainoid score	I3127
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3033
Inparanoid	1	1.050	389	1.000	Inparanoid score	I1936
OMA	1	1.010	-	-		QHG63565
OrthoDB	1	1.010	-	-		D1324510at2759
OrthoFinder	1	1.000	-	-		FOG0004755
OrthoInspector	1	1.000	-	-		oto96869
orthoMCL	1	0.900	-	-		OOG6_101920
Panther	1	1.100	-	-	LDO	PTHR11938
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3346
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.980