DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dare and su(r)

DIOPT Version :9

Sequence 1:	NP_477150.1	Gene:	dare / 36203	FlyBaseID:	FBgn0015582	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_727320.1	Gene:	su(r) / 31858	FlyBaseID:	FBgn0086450	Length:	1031	Species:	Drosophila melanogaster

Alignment Length:	479	Identity:	103/479 - (21%)
Similarity:	164/479 - (34%)	Gaps:	144/479 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 RLQVIQSTTP-------TKRICIVGAGPAGFYAAQLILKQLDNCVVDVVEKLPVPFGLVRFGVAP 76
            ::.|.|..||       :::|.:||.|||....| ..|.:|....|.:.|:.....||    .|.
  Fly   167 KMGVRQRRTPQAEANPLSQKIALVGGGPASLSCA-TFLARLGYRDVTIYERRSYLGGL----SAA 226

  Fly    77 DHPEVK---NVINTFTKTAEHPRLRYFGNISLGT-DVSLRELRDRYH-AVLLTYGADQDRQLELE 136
            :.|:.:   :.:|..........:|.....|||| |::::.|....| ||.:..|        |.
  Fly   227 EIPQYRLPIDAVNFEIDLVRDLGVRIETGRSLGTKDLTIQGLLSTGHDAVFVGIG--------LP 283

  Fly   137 NEQLDNVIS----ARKFVAWYNGLP--------------GAENLAPDLSGRDVTIVGQGNVAVDV 183
            ..:|:.:.:    :..|....|.||              .|..| |.|.| :|.::|.|:.|.|.
  Fly   284 EPKLNPIFAGLQPSNGFYTSKNFLPLVSDGSKPGLCACKAAAGL-PKLHG-NVIVLGAGDTAFDC 346

  Fly   184 ARMLLSPLDALKTTDTTEYALEALSCSQVERVHLVGRRGPLQAAFTIKELREMLKLPNVDTRWRT 248
                               |..||.|. ..||.:|.|:|.
  Fly   347 -------------------ATSALRCG-ARRVFVVFRKGS------------------------- 366

  Fly   249 EDFSGIDMQLDKLQRPRKRLTELM-----LKSLKEQGRISGSKQFLPIFLRAPKAIAPGEMEFSV 308
               |||....::::..|....||:     .|.:.:.|.|:.                   |||..
  Fly   367 ---SGIRAVPEEVELARDERCELLPYLSPRKVIVKDGLITA-------------------MEFCR 409

  Fly   309 TELQQ--EAAVPTSSTERLPSHLILRSIGYKSSCVDTGINFDTR----RGRVHNINGRILKDDAT 367
            ||..:  |.......|:||.::.::.:.|  |...|..:.....    ||.:..:: |:....:.
  Fly   410 TEQNENDEWVEDEEQTQRLKANFVISAFG--SGLEDQDVKAALAPLQFRGELPVVD-RVTMQSSV 471

  Fly   368 GEVDPGLYVAGWLGTGPTGVIVTT---MNGAFAVAKTICDDINTNALDTSSVKPGYDADGKRV-- 427
            .:|        :||....||..||   :|.....|.:|...:....|||.:..|.:..|...|
  Fly   472 KQV--------FLGGDLAGVANTTVESVNDGKVAAWSIHCQLQGLPLDTPAALPLFYTDIDAVDI 528

  Fly   428 -VTWDGWQRINDFESAAGKAKGKP 450
             |...|.:    ||:..|.|...|
  Fly   529 SVEMCGIR----FENPFGLASAPP 548

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dare	NP_477150.1	PLN02852	10..465	CDD:215457	103/479 (22%)
dare	NP_477150.1	NAD_binding_8	34..98	CDD:290186	15/66 (23%)
su(r)	NP_727320.1	PRK11749	55..507	CDD:236967	90/432 (21%)
		Fer4_20	58..170	CDD:291363	0/2 (0%)
		NAD_binding_8	190..>234	CDD:290186	14/48 (29%)
		PRK08318	527..1008	CDD:236237	7/26 (27%)
		DHPD_FMN	527..829	CDD:239244	7/26 (27%)
		Fer4_9	953..997	CDD:289930
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445079
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840