Protein Alignment Fbl6 and Fbxl16

DIOPT Version :10

• Sequence 1: NP_610665.2
• Gene: Fbl6 / 36201
• FlyBaseID: FBgn0033609
• Length: 720
• Species: Drosophila melanogaster
• Sequence 2: XP_038942467.1
• Gene: Fbxl16 / 494223
• RGDID: 1309127
• Length: 488
• Species: Rattus norvegicus
• Alignment Length: 611
• Identity: 127/611 - (20%)
• Similarity: 210/611 - (34%)
• Gaps: 177/611 - (28%)

  Fly   120 SPASDGQRSPAADQQSSAPPPQVQAQATPAPVNGSVPKSGKPLSTALSGKKTSKAATTSPRASRC 184
            ||..||...|:.                 .|.||.|...|:|
  Rat     3 SPGIDGDPKPSC-----------------LPRNGLVKLPGQP----------------------- 27

  Fly   185 RKTKALPMYESEISDNKMGIRLCIKKSDAGEGAPAGVTSPPVAVPAATKTVRKRVRKPKQQDSDE 249
                           |.:|.....|.:.|.:..|.....||...|.:..|...||..
  Rat    28 ---------------NGLGAASITKGTPAAKNRPCQPPPPPTLPPPSLATPLSRVAL-------- 69

  Fly   250 AEYEPRKKKGGGGGSGGEKKVSTSPDAAEAAGDPVEQSVWAQKLPEEVLFRIFEHAVDTQGCLPT 314
                          :||....::.|.:....|.|||:...|  ..|::|..:|.:....:.|:
  Rat    70 --------------AGGPCPPASGPASGPVPGPPVERPPLA--TDEKILNGLFWYFSACEKCI-- 116

  Fly   315 LFRLGRVCSLWRQVSLRPTLWRTMDLTTWVKEKY-------RTELKLKWFVDNRCSACTDLNVSN 372
               |.:||..||:|..:|..|..:......||.|       :..:.|:.|..........:.||:
  Rat   117 ---LAQVCKAWRRVLYQPKFWAGLTPVLHAKELYNVLPGGEKEFVNLQGFAARGFEGFCLVGVSD 178

  Fly   373 WKISDI--NCFLAKLSSGCPNLAGITLSGWKGFTSDHLTYLVDNMHKLQRLDLSSINVEMNASKS 435
            ..|.:.  |..|:|......:|...|:      |...|..:::.|..:.||:||
  Rat   179 LDICEFIDNYSLSKKGVKAMSLKRSTI------TDAGLEVMLEQMQGVVRLELS----------- 226

  Fly   436 AVGVNSLCNA--LQTMGSRLTHL------YLAHNRLAGIPQIVGILSTHCPNLTLLDLS--NVTT 490
              |.|....|  ..::.:|:|.|      .:|.:.:|.|.|::       |||..|.|.  :||.
  Rat   227 --GCNDFTEAGLWSSLSARITSLSVSDCINVADDAIAAISQLL-------PNLAELSLQAYHVTD 282

  Fly   491 QATSHGVLHIEKLQRGCQKLKVLRVTNSHITPSTASMQEIMDSPGFPELEELSVAALTDESRIIS 555
            .|.::............:.|....:||..:.....|:         |.|..||::..:.    ::
  Rat   283 TALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSL---------PNLTSLSLSGCSK----VT 334

  Fly   556 DDHLQRILKSSSKLKLLDVRNCTRLTHESL--IRLPAWDIKHLFLSGCSVTRDMGSGLELIASKW 618
            ||.::.:.::..||:.||:..|.|:|..:|  :......::.|.|..|:.....|         |
  Rat   335 DDGVELVAENLRKLRSLDLSWCPRITDMALEYVACDLHRLEELVLDRCTHPYTPG---------W 390

  Fly   619 AHSLIELDLAWANMQQPIDNALRALAEKGRDSPLAHLNLCGSSVSDEAVKEILTNCQNMSSINLA 683
            ...:.:..|::.:..    ::||:|          :|..| ..|.|..:|.:|.    |.|:.|.
  Rat   391 CVRITDTGLSYLSTM----SSLRSL----------YLRWC-CQVQDFGLKHLLA----MRSLRLL 436

  Fly   684 SCRGLP----RGVKRLMQGPQELGEL 705
            |..|.|    .|:..|:| .|||.||
  Rat   437 SLAGCPLLTTTGLSGLVQ-LQELEEL 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fbl6	NP_610665.2	PLN03237	<3..254	CDD:215641	22/133 (17%)
		F-box_FBXL6	291..336	CDD:438891	11/44 (25%)
		leucine-rich repeat	365..391	CDD:275381	6/27 (22%)
		LRR	<366..>521	CDD:443914	36/166 (22%)
		leucine-rich repeat	392..417	CDD:275381	5/24 (21%)
		leucine-rich repeat	418..445	CDD:275381	6/26 (23%)
		leucine-rich repeat	453..471	CDD:275381	6/23 (26%)
		leucine-rich repeat	480..509	CDD:275381	6/30 (20%)
		leucine-rich repeat	510..538	CDD:275381	4/27 (15%)
		leucine-rich repeat	539..579	CDD:275381	10/39 (26%)
		leucine-rich repeat	580..621	CDD:275381	7/42 (17%)
		leucine-rich repeat	622..649	CDD:275381	4/26 (15%)
		leucine-rich repeat	652..676	CDD:275381	6/23 (26%)
		leucine-rich repeat	677..698	CDD:275381	8/24 (33%)
Fbxl16	XP_038942467.1	F-box_FBXL16	95..136	CDD:438899	13/47 (28%)
		leucine-rich repeat	195..219	CDD:275381	5/29 (17%)
		AMN1	201..422	CDD:187754	56/283 (20%)
		leucine-rich repeat	220..243	CDD:275381	7/35 (20%)
		leucine-rich repeat	244..269	CDD:275381	6/31 (19%)
		leucine-rich repeat	270..321	CDD:275381	10/59 (17%)
		leucine-rich repeat	322..347	CDD:275381	5/28 (18%)
		leucine-rich repeat	348..373	CDD:275381	7/24 (29%)
		leucine-rich repeat	374..407	CDD:275381	6/45 (13%)
		leucine-rich repeat	408..427	CDD:275381	8/29 (28%)