DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fbl6 and Kdm2

DIOPT Version :9

Sequence 1:NP_610665.2 Gene:Fbl6 / 36201 FlyBaseID:FBgn0033609 Length:720 Species:Drosophila melanogaster
Sequence 2:NP_001262400.1 Gene:Kdm2 / 41090 FlyBaseID:FBgn0037659 Length:1345 Species:Drosophila melanogaster


Alignment Length:604 Identity:120/604 - (19%)
Similarity:200/604 - (33%) Gaps:198/604 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    64 DINTLTPSTPSQTPPQLLAVET-----ATSGSTAVIPENILSPPKSETQTDETNTATSTS--CSP 121
            |.|||.|....|....:...|:     ..||........:....:.|.:|:..|:..:.|  .||
  Fly   841 DGNTLLPPPVGQYNDFVFTSESEMESGTVSGHMTHWKHGMKRHHQLEVKTERNNSCDTPSPGISP 905

  Fly   122 ASDGQRSPAADQQSSAPPPQVQA---QATPAPVNGSVPKSGKPLSTALSGKKTSKAATT----SP 179
            .:.|..|....::.|.....|.:   ::..||...|...:|        |...:..:|.    |.
  Fly   906 NAIGGDSKVGKRRKSDDGTSVSSSMHESNDAPCGSSAEGAG--------GAGNANVSTNQWSGSG 962

  Fly   180 RASRCRKTKALPMYESEISDNKMGIRLCIKK---------------SDAGEGAPAGVTSPPVAVP 229
            .....||..::   .|:::...:.....:.|               |.:|.|..|          
  Fly   963 GGGGSRKKNSI---RSQLAQQMLNSSTRVLKKPQYVVRPASGTGSSSSSGNGGSA---------- 1014

  Fly   230 AATKTVRKRVRKPKQQDSDEAEYEPRKKKGGGGGSG--GEKKVSTSPDAAEAAGDPVEQSVWAQK 292
            :||..:.....:...........|.....||..||.  |.:..|:|.:.|.   ||....:..:.
  Fly  1015 SATNGISNGSNQSGANSCGAGNGERGTNNGGLSGSNGLGNQHYSSSQNLAL---DPTVLKIIFRY 1076

  Fly   293 LPEEVLFRIFEHAVDTQGCLPTLFRLGRVCSLWRQVSLRPTLWRTMD---------LTTWVKEKY 348
            ||::                 ||.....||.:|...::.|.||:.|:         |.|.:..:.
  Fly  1077 LPQD-----------------TLVTCCSVCKVWSNAAVDPDLWKKMNCSEHKMSASLLTAIVRRQ 1124

  Fly   349 RTELKLKW---------FVDNRCSACTDLNVSNWKISDINCFLAKLSSGCPNLAGITLSGWKGFT 404
            ...|.|.|         ::..|..|..:|::.|..|..:   ||..:..||.|..:.||..:|..
  Fly  1125 PEHLILDWTQIAKRQLAWLVARLPALKNLSLQNCPIQAV---LALHTCLCPPLQTLDLSFVRGLN 1186

  Fly   405 ------------------SDHLTYLVD-NMHKLQRLDLSSINVEMNASKSAVGVNSLCNALQTMG 450
                              ||..|.|.| .:.||...|:|.           |.|..:..:|.   
  Fly  1187 DAAIRDILSPPKDSRPGLSDSKTRLRDLKVMKLAGTDISD-----------VAVRYITQSLP--- 1237

  Fly   451 SRLTHLYLAHNRLAGIPQIVGILSTHCPNLTLLDLSNVTTQATSHGVLHIEKLQRGCQKLKVLRV 515
                  ||.|                      ||||:                   ||     |:
  Fly  1238 ------YLRH----------------------LDLSS-------------------CQ-----RI 1250

  Fly   516 TNSHI----TPSTASMQEIMDSPGFPELEELSVAALTDESRIISDDHLQRILKSSSKLKLLDVRN 576
            |::.:    |.:||:.:          |.||:::|    .|::|::.|:.:.|... |..||:|:
  Fly  1251 TDAGVAQIGTSTTATAR----------LTELNLSA----CRLVSENALEHLAKCEG-LIWLDLRH 1300

  Fly   577 CTRLTHESLIRLPAWDIKH 595
            ..:::.:|:||. |.:.||
  Fly  1301 VPQVSTQSVIRF-ASNSKH 1318

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fbl6NP_610665.2 F-box-like 293..341 CDD:289689 11/56 (20%)
leucine-rich repeat 365..391 CDD:275381 6/25 (24%)
leucine-rich repeat 392..417 CDD:275381 9/43 (21%)
leucine-rich repeat 418..445 CDD:275381 5/26 (19%)
leucine-rich repeat 453..471 CDD:275381 3/17 (18%)
leucine-rich repeat 480..509 CDD:275381 5/28 (18%)
leucine-rich repeat 510..538 CDD:275381 5/31 (16%)
leucine-rich repeat 539..579 CDD:275381 12/39 (31%)
leucine-rich repeat 580..621 CDD:275381 6/16 (38%)
leucine-rich repeat 622..649 CDD:275381
leucine-rich repeat 652..676 CDD:275381
leucine-rich repeat 677..698 CDD:275381
Kdm2NP_001262400.1 cupin_like 231..331 CDD:304367
PRTases_typeI <394..>467 CDD:294217
zf-CXXC 670..716 CDD:251032
PHD_4 721..801 CDD:293471
F-box-like <1073..1108 CDD:289689 11/51 (22%)
leucine-rich repeat 1102..1125 CDD:275381 4/22 (18%)
leucine-rich repeat 1126..1149 CDD:275381 4/22 (18%)
leucine-rich repeat 1150..1173 CDD:275381 6/25 (24%)
AMN1 1166..>1320 CDD:187754 50/235 (21%)
leucine-rich repeat 1174..1213 CDD:275381 8/38 (21%)
leucine-rich repeat 1214..1238 CDD:275381 7/43 (16%)
leucine-rich repeat 1239..1267 CDD:275381 13/73 (18%)
leucine-rich repeat 1268..1292 CDD:275381 8/27 (30%)
leucine-rich repeat 1293..1317 CDD:275381 8/24 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.810

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