Protein Alignment Fbl6 and fbxl6

DIOPT Version :10

• Sequence 1: NP_610665.2
• Gene: Fbl6 / 36201
• FlyBaseID: FBgn0033609
• Length: 720
• Species: Drosophila melanogaster
• Sequence 2: NP_001296447.1
• Gene: fbxl6 / 323163
• ZFINID: ZDB-GENE-060810-162
• Length: 564
• Species: Danio rerio
• Alignment Length: 603
• Identity: 164/603 - (27%)
• Similarity: 269/603 - (44%)
• Gaps: 105/603 - (17%)

  Fly   163 STALSGKKTSKAATTSPRASRCRKTKALPMYESEISDNKMGIRLCIKKSDAGEGAPAGVTSPPVA 227
            |..:|..::|: |.|||.....||. .|......:.|:|.      ||.          ...||
Zfish    10 SAEMSAAQSSR-AETSPTKPAKRKA-PLKRKADSLKDDKS------KKK----------KRKPV- 55

  Fly   228 VPAATKTVRKRVRKPKQQD---------SDEAEYEPRKKKGGGGGSGGEKKVSTSPDAAEAAGDP 283
                .:|||......:.:|         |.::.::|::|.|....:..:.|...|....|.|  |
Zfish    56 ----KRTVRPNYTVQEGEDMLLIISNISSGDSVWKPKRKVGKKKKTNKKAKTKGSTSKKEKA--P 114

  Fly   284 VEQSV------------------------WAQKLPEEVLFRIFEHAVDTQGCLPTLFRLGRVCSL 324
            |:..|                        |.|.||.|:|.:||:.||...|.:|.|.|:||||.|
Zfish   115 VKTEVLKVREETDDKHDVMDSAKTDRFDHWGQSLPLEILVKIFQFAVFQDGAVPLLCRVGRVCRL 179

  Fly   325 WRQVSLRPTLWRTMDL-TTWVK----EKYRTELKLK----WFVDNRCSACTDLNVSNWKISDINC 380
            |...:..|.|||::.: ..|::    :...||.|:|    |..:||.....:.::.:|| .:::.
Zfish   180 WNGAASSPILWRSVSIGYCWIEPGKSQLPGTEQKIKNTVDWLAENRLFQLREFSLCHWK-KNVDY 243

  Fly   381 FLAKLSSGCPNLAGITLSGWKGFTSDHLTYLVDNMHKLQRLDLSSINVEMNASKSAVGVNSLCNA 445
            .:.|:|..|.:|..:.||...|.|......|..:...|:         ::|...|.:.|:.|.:.
Zfish   244 VIQKVSQSCLSLHSLKLSYCTGMTEKAFQNLGADCQSLE---------DINVQHSEINVDGLVSF 299

  Fly   446 LQTMGSRLTHLYLAHNRLAGIPQIVGILSTH-CPNLTLLDLSNVTTQATSHGVLHIEKLQRGCQK 509
            |:..|:::..:|..|:..:  .:::..||.. ||.|.||:::.......|...:.|:.||.||.|
Zfish   300 LEAYGNQIKKIYFTHSTKS--DKLLSALSKGCCPELRLLEINTKLDGGYSQLPICIQGLQIGCPK 362

  Fly   510 LKVLRVTNSHITPSTASMQEIMDSP-GFPELEELSVAALTDESRIISDDHLQRILKSSSKLKLLD 573
            |:..|:.|  :|.....::.|..|. |||.||||.:|  |.....::|:.|..:|..|..|::||
Zfish   363 LQTFRLMN--VTAVPKMIRNIPSSTCGFPMLEELCIA--TSFHSFMTDNDLNNVLHGSPNLRVLD 423

  Fly   574 VRNCTRLTHESLIRLPA-------WDIKHLFLSGCSVTRDMGSGLELIASKWAHSLIELDLAWAN 631
            :|..:|:|...|..||.       |.:  .|.|...|...  .|:.::|.||:::|.|||||
Zfish   424 LRGGSRITPTGLYALPCERLECFYWGL--YFNSNTMVASK--KGIHMLAQKWSNTLRELDLA--- 481

  Fly   632 MQQP-----IDNALRALAEKGRDSPLAHLNLCGSSVSDEAVKEILTNCQNMSSINLASCRGLPRG 691
             .||     ::.|:..||..........|||.|:.::..|::.::.....:..:||:|||.||||
Zfish   482 -NQPFSEEDLEIAMGHLAHSVGVEFFRSLNLSGTKITSSALRLLINQAPALKYLNLSSCRYLPRG 545

  Fly   692 VKRLMQGPQELGELREVL 709
            :|||..|.:::..|.:.|
Zfish   546 LKRLYHGQEDIQLLLDKL 563

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fbl6	NP_610665.2	PLN03237	<3..254	CDD:215641	21/99 (21%)
		F-box_FBXL6	291..336	CDD:438891	21/44 (48%)
		leucine-rich repeat	365..391	CDD:275381	5/25 (20%)
		LRR	<366..>521	CDD:443914	37/155 (24%)
		leucine-rich repeat	392..417	CDD:275381	6/24 (25%)
		leucine-rich repeat	418..445	CDD:275381	5/26 (19%)
		leucine-rich repeat	453..471	CDD:275381	2/17 (12%)
		leucine-rich repeat	480..509	CDD:275381	9/28 (32%)
		leucine-rich repeat	510..538	CDD:275381	8/28 (29%)
		leucine-rich repeat	539..579	CDD:275381	14/39 (36%)
		leucine-rich repeat	580..621	CDD:275381	12/47 (26%)
		leucine-rich repeat	622..649	CDD:275381	11/31 (35%)
		leucine-rich repeat	652..676	CDD:275381	5/23 (22%)
		leucine-rich repeat	677..698	CDD:275381	12/20 (60%)
fbxl6	NP_001296447.1	F-box_FBXL6	145..191	CDD:438891	21/45 (47%)
		AMN1	213..396	CDD:187754	52/196 (27%)
		leucine-rich repeat	229..254	CDD:275381	5/25 (20%)
		leucine-rich repeat	255..280	CDD:275381	6/24 (25%)
		leucine-rich repeat	281..306	CDD:275381	7/33 (21%)
		leucine-rich repeat	307..334	CDD:275381	6/28 (21%)
		leucine-rich repeat	335..362	CDD:275381	8/26 (31%)
		AMN1	<391..>542	CDD:187754	48/160 (30%)
		leucine-rich repeat	391..418	CDD:275381	10/28 (36%)
		leucine-rich repeat	419..438	CDD:275381	7/18 (39%)
		leucine-rich repeat	445..473	CDD:275381	8/31 (26%)
		leucine-rich repeat	475..505	CDD:275381	11/33 (33%)
		leucine-rich repeat	506..530	CDD:275381	5/23 (22%)