Protein Alignment Fbl6 and LOC1280739

DIOPT Version :10

• Sequence 1: NP_610665.2
• Gene: Fbl6 / 36201
• FlyBaseID: FBgn0033609
• Length: 720
• Species: Drosophila melanogaster
• Sequence 2: XP_320603.4
• Gene: LOC1280739 / 1280739
• VectorBaseID: AGAMI1_004046
• Length: 669
• Species: Anopheles gambiae
• Alignment Length: 742
• Identity: 138/742 - (18%)
• Similarity: 252/742 - (33%)
• Gaps: 284/742 - (38%)

  Fly   137 APPPQVQAQATPAPVNGSVPKSGKPLSTALSGKKTSKAATTSPRASRCRKTKALPMYESEI--SD 199
            ||.|:::....|.|     .:.|:..:..:..||..|     |:|     |...|..|.|:  ..
Mosquito    16 APVPEMEMLTLPFP-----KEDGEHTNGVVETKKKKK-----PKA-----TPKQPTPEPEVFTGF 65

  Fly   200 NKMGIRLCIK---------KSDAGEGAPAGVTSPPVAVPAATKTVRKRVRKPKQQDSDEAEYEPR 255
            |.:.:.|.:|         :...|:.....:.:....:|.:.:.:.:..      :.:..:|||
Mosquito    66 NYLPMELLLKVMKQISVDDRLACGQTCHRWMEAAHYYLPFSDRIIYRFT------NVNFTDYEP- 123

  Fly   256 KKKGGGGGSGGEKKVSTSPDAAEAAGDPVEQSVWAQKLPEEVLFRIF------------------ 302
                                       |::..:.|        ||||
Mosquito   124 ---------------------------PIKSFLGA--------FRIFPRIAIKACTFYGNSQFWP 153

  Fly   303 ---EHAVD--TQGCL----PTLFRLGRVCSLWRQVSLRPTLWRTMDLTTWVKEKYRTELKLKWFV 358
               ||.::  .:.||    ..|:.|..|.:| ||:.:...                .||...|:.
Mosquito   154 LFGEHVIELTIKNCLIKDTELLYILEHVPNL-RQLKIEQC----------------DELFRSWYF 201

  Fly   359 DNRCSAC---------TDLNVSNWKISDINCFL-----AKLSSGCPNLAGITLSG-WKGFTSDHL 408
            :.|.|.|         .|::::|      |.||     .||.:..||:|.:.||. :|...|...
Mosquito   202 EKRQSCCESHFVLPDLLDVSLTN------NDFLDELHFNKLMTLAPNIAHLDLSNCFKMIASHRR 260

  Fly   409 TYLVD------NMHKLQR------------------------------------------LDLSS 425
            ..:|:      |||:.|.                                          :||..
Mosquito   261 VAMVEHIMRFINMHQFQLHTLKFNGTLAIDDICLSTLSMIEGLSLETFSMTFCDKIPAAIIDLLR 325

  Fly   426 INVEMNASK--------------------------------SAVGV-NSLCNALQTMGSRLTHLY 457
            ...::|.::                                |::|: :.:...:.|...:|..|.
Mosquito   326 RQPDLNITQDLEWKVGRHPIKAPGFISFLVRQTNLVHLDLTSSLGITDEVMELITTCLPKLKTLK 390

  Fly   458 LAHNRLA---GIPQIVGILSTHCPNLTLLDLSN---VTTQATSHGV-------LH---------- 499
            |....|.   ||..||.::     ||.:|||||   ::..|...||       ||
Mosquito   391 LRRCILVTDEGIMNIVNLV-----NLEVLDLSNCYRISDHAMYRGVIGRKVKNLHELYLCELPTL 450

  Fly   500 ----IEKLQRGCQKLKVLRVTNSHITPSTASMQEIMDSPGFPELEELSV---AALTDE------- 550
                :.::....:.|:||.::||....:.|:||.:  :.....|::|.:   ..|||.
Mosquito   451 SDYSLIQVTLNYEMLQVLDLSNSPNAATDATMQYV--NYYLVSLKQLHLYCCTKLTDSGLTGIDL 513

  Fly   551 --SRIISDDH-----LQRILKSSSKLKLLDVRNCTRLTH---ESLIRLPAWDIKHLFLSGCSVTR 605
              ..:|:.|.     |.|:.    ||::|::..|.|:|.   |:..:|.  ::|.|.|:.|....
Mosquito   514 PVKPMITWDQEETFPLDRLF----KLRVLNLIGCYRITDLSLENAFKLA--ELKELHLARCYQIS 572

  Fly   606 DMGSGLELIASKWAHSLIELDLAWANMQQPI--DNALRALAEKGRDSPLAHLNLCGSSVSDEAVK 668
            :.|..   :.|:.|.:|..:||:    :.|:  ||.:..|....:......:|.| ..:::..::
Mosquito   573 EKGIA---VLSQVATALEFIDLS----ECPLVNDNCIEMLTANLKRLRTLKVNKC-PQLTNACLE 629

  Fly   669 EILTNCQNMSSINLASCRGLPRGVKRL 695
            .|..||..:..:::..||.:.:..:||
Mosquito   630 IIGRNCSYLKYLHMIDCRRVRKPRERL 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fbl6	NP_610665.2	PLN03237	<3..254	CDD:215641	21/127 (17%)
		F-box_FBXL6	291..336	CDD:438891	14/71 (20%)
		leucine-rich repeat	365..391	CDD:275381	8/39 (21%)
		LRR	<366..>521	CDD:443914	50/268 (19%)
		leucine-rich repeat	392..417	CDD:275381	8/31 (26%)
		leucine-rich repeat	418..445	CDD:275381	6/101 (6%)
		leucine-rich repeat	453..471	CDD:275381	7/20 (35%)
		leucine-rich repeat	480..509	CDD:275381	11/52 (21%)
		leucine-rich repeat	510..538	CDD:275381	8/27 (30%)
		leucine-rich repeat	539..579	CDD:275381	13/56 (23%)
		leucine-rich repeat	580..621	CDD:275381	10/43 (23%)
		leucine-rich repeat	622..649	CDD:275381	7/28 (25%)
		leucine-rich repeat	652..676	CDD:275381	5/23 (22%)
		leucine-rich repeat	677..698	CDD:275381	4/19 (21%)
LOC1280739	XP_320603.4	None