Protein Alignment Fbl6 and Fbxl7

DIOPT Version :10

• Sequence 1: NP_610665.2
• Gene: Fbl6 / 36201
• FlyBaseID: FBgn0033609
• Length: 720
• Species: Drosophila melanogaster
• Sequence 2: XP_061500383.1
• Gene: Fbxl7 / 1267513
• VectorBaseID: AGAMI1_014086
• Length: 841
• Species: Anopheles gambiae
• Alignment Length: 728
• Identity: 150/728 - (20%)
• Similarity: 252/728 - (34%)
• Gaps: 173/728 - (23%)

  Fly    31 DSAETAMEVEADDTGGQQPEQSELLDKEKSATVDINTLTPSTPSQTPPQLLAVETATSGSTA--- 92
            |..::|:       ||........|: ||...:.|........:.||..|...::::|.:|.
Mosquito   189 DEPQSAL-------GGLSEADRYFLE-EKMDALYIQGAIRRNANATPSSLTRNQSSSSNNTERYY 245

  Fly    93 VIPENI------------------LSPPKSETQTDETNTATSTSCSPASD-----GQRSPAADQQ 134
            :..|||                  :.||.........:.|.|.:.|.|..     ...||...::
Mosquito   246 LENENIDAIYNFCRRNGGGGGGGGIGPPPGTVAAHNAHNAASKASSAAQSQVDCLDSSSPHLLRR 310

  Fly   135 SSAPPPQVQAQATPAPVNGSVPKSGKPLSTALSGKKTSKAATTS-------PRASRCRKTKALPM 192
            :|:|......:.....:.|| |....|..|.|      ||..::       |.......|..|..
Mosquito   311 ASSPETSGSDRYLLDRIRGS-PAFQSPRGTHL------KAVGSADFIDGRIPLTKSQHYTDGLSR 368

  Fly   193 YESEISDNKMGIRLCIKKSDAGE------------------GAPAGVTSPPVAVPAATKTVRKRV 239
            |.....:...|....:..|.:|:                  |.....||.....||.|.|
Mosquito   369 YGRFSPNLDQGYHTLVSPSPSGQQQSTIPASWTTGGTHGSGGGGTNSTSSSHGSPAQTNT----- 428

  Fly   240 RKPKQQDSDEAEYEPRKKKGGGGGSGGEKKVSTSPDAA---EAAGDPVEQSVWA-----QKLPEE 296
                             ..||.|.:.|......|.|.|   .:.|:....|::.     .::|:|
Mosquito   429 -----------------PVGGNGSANGNGPCGRSIDGATILTSLGNGHGTSLYRAGPLFDRMPDE 476

  Fly   297 VLFRIFEHAVDTQGCLPTLFRLGRVCSLWRQVSLRPTLWRTMDLTTWVKEKYRTELKLKWFVDNR 361
            ::.||||....::.|     .:.|||..:..|...|.||:.:.:.   .|:...:..:|..:...
Mosquito   477 LMVRIFEWLDSSELC-----NIARVCRRFESVIWNPALWKIIKIK---GEENSGDRAIKTILRRL 533

  Fly   362 C-----SACTD----LNVSNWKISDINCFLAKLSSGCPNLAGITLSGWKGFTSDHLTYLVDNMHK 417
            |     .||..    |.....:::|..  |..||..||.:..:.:......|:..|:.||.....
Mosquito   534 CGQTRNGACPGVERVLLADGCRLTDRG--LQLLSRRCPEITHLQIQNSVTITNQALSDLVTKCTN 596

  Fly   418 LQRLDLSSINVEMNASKSAVGVNSLCNALQTMGSRLTHLYLAHNRLAGIPQI-VGILSTHCPNLT 481
            ||.||::..     |..:.:.:|.   .|:. ..||...||.....|.|... :.:::.:||.|.
Mosquito   597 LQHLDITGC-----AQITCININP---GLEP-PRRLLLQYLDLTDCASICDAGIKVIARNCPLLV 652

  Fly   482 LLDLSNVTTQATSHGVLHIEKLQRGCQKLKVLRVTNSHITPSTASMQEIMDSPGF-PELEELSVA 545
            .|.|                   |.|     ::||:       |.::.|   |.| ..|.||||:
Mosquito   653 YLYL-------------------RRC-----IQVTD-------AGLKFI---PNFCIALRELSVS 683

  Fly   546 ALTDESRIISDDHLQRILKSSSKLKLLDVRNCTRLTHESL--IRLPAWDIKHLFLSGCSVTRDMG 608
            ..|.    ::|..|..:.|..:.|:.|.|..|.:::...|  |....:.:::|...||....|
Mosquito   684 DCTS----VTDFGLYELAKLGATLRYLSVAKCDQVSDAGLKVIARRCYKLRYLNARGCEAVSD-- 742

  Fly   609 SGLELIASKWAHSLIELDLAWANMQQPIDNALRALAEKGRDSPLAHLNLCGSSVSDEAVKEILTN 673
            ..:.::| :....|..||:...::.   |..||||||...:.....|..| ..::|..::.|...
Mosquito   743 DSINVLA-RSCPRLRALDIGKCDVS---DAGLRALAESCPNLKKLSLRNC-DMITDRGIQCIAYY 802

  Fly   674 CQNMSSINLASCR 686
            |:.:..:|:..|:
Mosquito   803 CRGLQQLNIQDCQ 815

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fbl6	NP_610665.2	PLN03237	<3..254	CDD:215641	48/273 (18%)
		F-box_FBXL6	291..336	CDD:438891	13/44 (30%)
		leucine-rich repeat	365..391	CDD:275381	7/29 (24%)
		LRR	<366..>521	CDD:443914	33/159 (21%)
		leucine-rich repeat	392..417	CDD:275381	4/24 (17%)
		leucine-rich repeat	418..445	CDD:275381	6/26 (23%)
		leucine-rich repeat	453..471	CDD:275381	5/18 (28%)
		leucine-rich repeat	480..509	CDD:275381	5/28 (18%)
		leucine-rich repeat	510..538	CDD:275381	6/28 (21%)
		leucine-rich repeat	539..579	CDD:275381	13/39 (33%)
		leucine-rich repeat	580..621	CDD:275381	7/42 (17%)
		leucine-rich repeat	622..649	CDD:275381	10/26 (38%)
		leucine-rich repeat	652..676	CDD:275381	5/23 (22%)
		leucine-rich repeat	677..698	CDD:275381	2/10 (20%)
Fbxl7	XP_061500383.1	None