Protein Alignment CG9062 and wdr48a

DIOPT Version :10

• Sequence 1: NP_001260886.1
• Gene: CG9062 / 36199
• FlyBaseID: FBgn0033607
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: NP_001410724.1
• Gene: wdr48a / 777754
• ZFINID: ZDB-GENE-061110-55
• Length: 678
• Species: Danio rerio
• Alignment Length: 690
• Identity: 385/690 - (55%)
• Similarity: 493/690 - (71%)
• Gaps: 44/690 - (6%)

  Fly     1 MLTH--KTCQARKKMQVSFVIRDAEEKQHRNGVNALQLDANNGKLYSAGRDAIIRVWNTRTDSSE 63
            |.||  :....|:|:|||:||||..||.:||||||||||....:|::||||:|||:|:......:
Zfish     1 MATHHRQNAAGRRKVQVSYVIRDEVEKYNRNGVNALQLDPALNRLFTAGRDSIIRIWSVNQHKQD 65

  Fly    64 KYIQSMEHHNDWVNDIVLCCNGRNLISASCDTTVKVWNAQKGFCMSTLRTHRDYVQALAYAKDRE 128
            .||.|||||.||||||||||||:.|||||.|||||||||.|||||||||||:|||:|||||||:|
Zfish    66 PYIASMEHHTDWVNDIVLCCNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKE 130

  Fly   129 QVASAGLDKAIFLWDVNTLTALTASNNTVTTSSLTGSKDSIYSLAMNPSGTVIVSGSTENILRIW 193
            .|||||||:.||||||||||||||||||||||||:|:||||||||||..||||||||||.:||:|
Zfish   131 LVASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQMGTVIVSGSTEKVLRVW 195

  Fly   194 DPRTCMRRMKLRGHTENVRCLVVSPDGNQVVSGSSDGTIKVWNLGQQRCVQTIHVHKEGVWSLLM 258
            |||||.:.|||:|||:||:.|:::.||.|.:||||||||::|:||||||:.|..||.||||:|.:
Zfish   196 DPRTCAKLMKLKGHTDNVKSLLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQV 260

  Fly   259 SENFQYIISGSRDRNIIVTEMRNPSNKTLVCEEQAPVLSLGYNIDKT-----GVWATTWNSDIRC 318
            :|.|.::.||.|||.|..|::|||..:.|:|||:||||.:  .:|::     .:|.:|..|.:..
Zfish   261 NEAFTHVYSGGRDRKIYCTDLRNPDIRVLICEEKAPVLKM--ELDRSADPHNAIWVSTTKSTVNK 323

  Fly   319 WKLPMYDRCTLNSSGGMDAQWTQGGTEVA-----CIKGGAAIKECAVLNDKRYIITKDSQDQVVV 378
            |.|....  ...:||..|...:...|.:.     .|||||:|.:|.:|||||:|:|||:.:.|..
Zfish   324 WSLKGIH--NFRASGDYDNDCSAPLTPLCTQPEQVIKGGASIIQCHILNDKRHILTKDTNNNVAY 386

  Fly   379 YDVLRVVKKEQLGAVDFEAEVKKRNKQVYIPNWFTVDLKTGMPTIVLGQEEVDCFSAWVSI-EAG 442
            :|||:..|.|.||.::|:.|:|||.|.||:||||:|||||||.||.|  :|.|||:||||. :||
Zfish   387 WDVLKACKVEDLGKMEFDEEIKKRFKMVYVPNWFSVDLKTGMLTITL--DESDCFAAWVSAKDAG 449

  Fly   443 L--PECVDPTTEIKINYGKLLLEALLEYWTPPHSIPPNEMEPDMH--------------GNGYFQ 491
            .  |:..||    |:|.|.|||:||||:|...| |.|.:.|.:::              ||||||
Zfish   450 FSSPDGSDP----KLNLGGLLLQALLEFWPRTH-INPMDEETELNHSSVNGEHESRIQKGNGYFQ 509

  Fly   492 VPKHTPVIFSEVGGRTVCRLLVRDAAGDSESTLLHETAPQWVTDVVIEKNIPKFLKIPFFLQPHP 556
            ||.||||||.|.||||:.|||.||:.|::||.||:||.||||.|:.::||:|||.||||:||||
Zfish   510 VPPHTPVIFGEAGGRTLFRLLCRDSGGETESMLLNETVPQWVIDITVDKNMPKFNKIPFYLQPH- 573

  Fly   557 QMTKPERTKKDRLVANEFIQCRKVCEHVLEKVLNAET-TPSGGNANNSLQNSQSDANSEGSQLPA 620
            ..:..:..|||||.|::.:|.|||.|||.||::|.:: :.:||:|.....:.|.:  .|...:.|
Zfish   574 SSSGAKTLKKDRLSASDMLQVRKVMEHVYEKIINLDSESQTGGSAAEKPSSEQKE--DEEMAVQA 636

  Fly   621 EERIELWCNDVVVDPNMDLRTVRHFIWKQSTDLTFQYKTK 660
            ||:|||.|.|.|:|||||||||:|||||...|||..|:.|
Zfish   637 EEKIELLCQDQVLDPNMDLRTVKHFIWKSGGDLTLHYRQK 676

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9062	NP_001260886.1	WD40	27..320	CDD:238121	193/297 (65%)
		WD40 repeat	77..113	CDD:293791	31/35 (89%)
		WD40 repeat	118..158	CDD:293791	34/39 (87%)
		WD40 repeat	170..205	CDD:293791	26/34 (76%)
		WD40 repeat	211..247	CDD:293791	21/35 (60%)
		WD40 repeat	253..288	CDD:293791	15/34 (44%)
		WD40 repeat	295..319	CDD:293791	6/28 (21%)
		DUF3337	492..658	CDD:463358	90/166 (54%)
wdr48a	NP_001410724.1	WD40	30..286	CDD:238121	181/255 (71%)
		WD40 repeat	35..73	CDD:293791	18/37 (49%)
		WD40 repeat	79..115	CDD:293791	31/35 (89%)
		WD40 repeat	120..160	CDD:293791	34/39 (87%)
		WD40 repeat	172..207	CDD:293791	26/34 (76%)
		WD40 repeat	213..249	CDD:293791	21/35 (60%)
		WD40 repeat	255..281	CDD:293791	12/25 (48%)
		DUF3337	510..674	CDD:463358	90/166 (54%)