Protein Alignment CG9062 and Wdr48

DIOPT Version :10

• Sequence 1: NP_001260886.1
• Gene: CG9062 / 36199
• FlyBaseID: FBgn0033607
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: NP_001404765.1
• Gene: Wdr48 / 67561
• MGIID: 1914811
• Length: 691
• Species: Mus musculus
• Alignment Length: 682
• Identity: 381/682 - (55%)
• Similarity: 484/682 - (70%)
• Gaps: 46/682 - (6%)

  Fly     8 QARKKMQVSFVIRDAEEKQHRNGVNALQLDANNGKLYSAGRDAIIRVWNTRTDSSEKYIQSMEHH 72
            :|.::.:||:||||..||.:||||||||||....:|::||||:|||:|:......:.||.|||||
Mouse    25 EASRRPRVSYVIRDEVEKYNRNGVNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHH 89

  Fly    73 NDWVNDIVLCCNGRNLISASCDTTVKVWNAQKGFCMSTLRTHRDYVQALAYAKDREQVASAGLDK 137
            .|||||:||||||:.|||||.|||||||||.|||||||||||:|||:|||||||:|.|||||||:
Mouse    90 TDWVNDVVLCCNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDR 154

  Fly   138 AIFLWDVNTLTALTASNNTVTTSSLTGSKDSIYSLAMNPSGTVIVSGSTENILRIWDPRTCMRRM 202
            .||||||||||||||||||||||||:|:||||||||||..||:|||||||.:||:||||||.:.|
Mouse   155 QIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLM 219

  Fly   203 KLRGHTENVRCLVVSPDGNQVVSGSSDGTIKVWNLGQQRCVQTIHVHKEGVWSLLMSENFQYIIS 267
            ||:|||:||:.|::..||.|.:||||||||::|:||||||:.|..||.||||:|.:::.|.::.|
Mouse   220 KLKGHTDNVKALLLHRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTHVYS 284

  Fly   268 GSRDRNIIVTEMRNPSNKTLVCEEQAPVLSLGYNIDKT-----GVWATTWNSDIRCWKLPMYDRC 327
            |.|||.|..|::|||..:.|:|||:||||.:  .:|::     .:|..|..|.:..|.|....
Mouse   285 GGRDRKIYCTDLRNPDIRVLICEEKAPVLKM--ELDRSADPPPAIWVATTKSTVNKWTLKGIH-- 345

  Fly   328 TLNSSGGMDAQWTQGGTEVA-----CIKGGAAIKECAVLNDKRYIITKDSQDQVVVYDVLRVVKK 387
            ...:||..|...|...|.:.     .|||||:|.:|.:|||||:|:|||:.:.|..:|||:..|.
Mouse   346 NFRASGDYDNDCTNPITPLCTQPDQVIKGGASIIQCHILNDKRHILTKDTNNNVAYWDVLKACKV 410

  Fly   388 EQLGAVDFEAEVKKRNKQVYIPNWFTVDLKTGMPTIVLGQEEVDCFSAWVSI-EAGL--PECVDP 449
            |.||.||||.|:|||.|.||:||||:|||||||.||.|  :|.|||:||||. :||.  |:..||
Mouse   411 EDLGKVDFEDEIKKRFKMVYVPNWFSVDLKTGMLTITL--DESDCFAAWVSAKDAGFSSPDGSDP 473

  Fly   450 TTEIKINYGKLLLEALLEYWTPPHSIPPNEMEPDMH------------GNGYFQVPKHTPVIFSE 502
                |:|.|.|||:||||||...|..|.:|.|.:::            ||||||||.||||||.|
Mouse   474 ----KLNLGGLLLQALLEYWPRTHVTPMDEEENEVNHVSGGQESRVQKGNGYFQVPPHTPVIFGE 534

  Fly   503 VGGRTVCRLLVRDAAGDSESTLLHETAPQWVTDVVIEKNIPKFLKIPFFLQPHPQMTKPERTKKD 567
            .||||:.|||.||:.|::|:.||:||.||||.|:.::||:|||.||||:||||.. :..:..|||
Mouse   535 AGGRTLFRLLCRDSGGETEAMLLNETVPQWVIDITVDKNMPKFNKIPFYLQPHAS-SGAKTLKKD 598

  Fly   568 RLVANEFIQCRKVCEHVLEKVLN----AETTPSGGNANNSLQNSQSDANSEGSQLPAEERIELWC 628
            ||.|::.:|.|||.|||.||::|    ::||.|..|.....:..:..|      :.|||:|||.|
Mouse   599 RLSASDMLQVRKVMEHVYEKIINLDNESQTTSSSNNEKPEQEKEEDIA------VLAEEKIELLC 657

  Fly   629 NDVVVDPNMDLRTVRHFIWKQSTDLTFQYKTK 660
            .|.|:|||||||||:|||||...|||..|:.|
Mouse   658 QDQVLDPNMDLRTVKHFIWKSGGDLTLHYRQK 689

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9062	NP_001260886.1	WD40	27..320	CDD:238121	190/297 (64%)
		WD40 repeat	77..113	CDD:293791	30/35 (86%)
		WD40 repeat	118..158	CDD:293791	34/39 (87%)
		WD40 repeat	170..205	CDD:293791	25/34 (74%)
		WD40 repeat	211..247	CDD:293791	21/35 (60%)
		WD40 repeat	253..288	CDD:293791	14/34 (41%)
		WD40 repeat	295..319	CDD:293791	6/28 (21%)
		DUF3337	492..658	CDD:463358	89/169 (53%)
Wdr48	NP_001404765.1	WD40	45..301	CDD:238121	178/255 (70%)
		WD40 repeat	50..88	CDD:293791	18/37 (49%)
		WD40 repeat	94..130	CDD:293791	30/35 (86%)
		WD40 repeat	135..175	CDD:293791	34/39 (87%)
		WD40 repeat	187..222	CDD:293791	25/34 (74%)
		WD40 repeat	228..264	CDD:293791	21/35 (60%)
		WD40 repeat	270..305	CDD:293791	14/34 (41%)
		WD40 repeat	312..339	CDD:293791	6/28 (21%)
		WD40 repeat	378..404	CDD:293791	12/25 (48%)
		DUF3337	524..687	CDD:463358	89/169 (53%)