Protein Alignment CG9062 and wdr48b

DIOPT Version :10

• Sequence 1: NP_001260886.1
• Gene: CG9062 / 36199
• FlyBaseID: FBgn0033607
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: NP_999874.1
• Gene: wdr48b / 334682
• ZFINID: ZDB-GENE-030131-6622
• Length: 677
• Species: Danio rerio
• Alignment Length: 689
• Identity: 384/689 - (55%)
• Similarity: 490/689 - (71%)
• Gaps: 47/689 - (6%)

  Fly     2 LTHKTCQARKKMQVSFVIRDAEEKQHRNGVNALQLDANNGKLYSAGRDAIIRVWNTRTDSSEKYI 66
            |..:....|:|:|||:||||..||.:||||||||||....:|::||||:|||:|:......:.||
Zfish     4 LHRQNAAGRRKVQVSYVIRDEVEKYNRNGVNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYI 68

  Fly    67 QSMEHHNDWVNDIVLCCNGRNLISASCDTTVKVWNAQKGFCMSTLRTHRDYVQALAYAKDREQVA 131
            .|||||.||||||:|||||:.|||||.|||||||||.|||||||||||:|||:|||||||:|.||
Zfish    69 ASMEHHTDWVNDIILCCNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVA 133

  Fly   132 SAGLDKAIFLWDVNTLTALTASNNTVTTSSLTGSKDSIYSLAMNPSGTVIVSGSTENILRIWDPR 196
            |||||:.||||||||||||||||||||||||:|:||||||||||.:||||:|||||.:||:||||
Zfish   134 SAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQTGTVIISGSTEKVLRVWDPR 198

  Fly   197 TCMRRMKLRGHTENVRCLVVSPDGNQVVSGSSDGTIKVWNLGQQRCVQTIHVHKEGVWSLLMSEN 261
            ||.:.|||:|||:||:.|:::.||.|.:||||||||::|:||||||:.|..||.||||:|.::|.
Zfish   199 TCAKLMKLKGHTDNVKSLLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNEA 263

  Fly   262 FQYIISGSRDRNIIVTEMRNPSNKTLVCEEQAPVLSLGYNIDKT-----GVWATTWNSDIRCWKL 321
            |.:|.||.|||.|..|::|||..:.|:|||:||||.:  .:|::     .:|.:|..|.:..|.|
Zfish   264 FTHIYSGGRDRKIYCTDLRNPDMRVLICEEKAPVLRM--ELDRSADPPQSIWVSTTKSFVNKWSL 326

  Fly   322 -PMYDRCTLNSSGGMDAQWTQGGTEVA-----CIKGGAAIKECAVLNDKRYIITKDSQDQVVVYD 380
             .|::   ..:||..|...:...|.:.     .||||.:|.:|.:|||||:|:|||:.:.|..:|
Zfish   327 KAMHN---FRASGDYDNDCSTPLTPLCTQPEQVIKGGTSIVQCHILNDKRHILTKDTNNSVAFWD 388

  Fly   381 VLRVVKKEQLGAVDFEAEVKKRNKQVYIPNWFTVDLKTGMPTIVLGQEEVDCFSAWVSI-EAGL- 443
            ||:..|.|.||.|||:.|||||.|.||:||||:|||||||.||.|  :|.|||:|||:. :||.
Zfish   389 VLKACKGEDLGKVDFDEEVKKRFKMVYVPNWFSVDLKTGMLTITL--DESDCFAAWVAAKDAGFT 451

  Fly   444 -PECVDPTTEIKINYGKLLLEALLEYWTPPHSIPPNEMEPDMH------------GNGYFQVPKH 495
             |:..||    |:|.|.|||:||||:|...|..|..|.|.:::            ||||||||.|
Zfish   452 SPDGSDP----KLNLGGLLLQALLEFWPRTHINPMEEEENELNHVNGEQESRIQKGNGYFQVPPH 512

  Fly   496 TPVIFSEVGGRTVCRLLVRDAAGDSESTLLHETAPQWVTDVVIEKNIPKFLKIPFFLQPHPQMTK 560
            |||||.|.||||:.|||.||:.|::||.||:||.||||.|:.::||:|||.||||:|||| ..:.
Zfish   513 TPVIFGEAGGRTLFRLLCRDSGGETESMLLNETVPQWVIDITVDKNMPKFNKIPFYLQPH-SSSG 576

  Fly   561 PERTKKDRLVANEFIQCRKVCEHVLEKVLN----AETTPSGGNANNSLQNSQSDANSEGSQLPAE 621
            .:..|||||.|::.:|.|||.|||.||::|    ::.|.|..|.....|..:.|.:     :.||
Zfish   577 AKTLKKDRLSASDMLQVRKVMEHVYEKIINLDMESQATSSSANDKPGEQEKEEDVS-----VMAE 636

  Fly   622 ERIELWCNDVVVDPNMDLRTVRHFIWKQSTDLTFQYKTK 660
            |:|||.|.|.|:|||||||||:|||||...|||..|:.|
Zfish   637 EKIELMCLDQVLDPNMDLRTVKHFIWKSGGDLTIHYRQK 675

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9062	NP_001260886.1	WD40	27..320	CDD:238121	192/297 (65%)
		WD40 repeat	77..113	CDD:293791	30/35 (86%)
		WD40 repeat	118..158	CDD:293791	34/39 (87%)
		WD40 repeat	170..205	CDD:293791	25/34 (74%)
		WD40 repeat	211..247	CDD:293791	21/35 (60%)
		WD40 repeat	253..288	CDD:293791	16/34 (47%)
		WD40 repeat	295..319	CDD:293791	6/28 (21%)
		DUF3337	492..658	CDD:463358	90/169 (53%)
wdr48b	NP_999874.1	WD 1	28..67		19/38 (50%)
		WD40	30..300	CDD:238121	188/269 (70%)
		WD40 repeat	35..73	CDD:293791	18/37 (49%)
		WD 2	73..112		32/38 (84%)
		WD40 repeat	79..115	CDD:293791	30/35 (86%)
		WD 3	115..154		32/38 (84%)
		WD40 repeat	120..160	CDD:293791	34/39 (87%)
		WD 4	166..205		28/38 (74%)
		WD40 repeat	172..207	CDD:293791	25/34 (74%)
		WD 5	208..247		24/38 (63%)
		WD40 repeat	213..249	CDD:293791	21/35 (60%)
		WD 6	250..289		20/38 (53%)
		WD40 repeat	255..281	CDD:293791	13/25 (52%)
		WD 7	292..334		13/46 (28%)
		WD40 repeat	300..330	CDD:293791	6/31 (19%)
		WD 8	358..397		19/38 (50%)
		DUF3337	509..673	CDD:463358	90/169 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	611..632		5/20 (25%)