DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TpnC47D and CALML6

DIOPT Version :9

Sequence 1:	NP_001286310.1	Gene:	TpnC47D / 36195	FlyBaseID:	FBgn0010423	Length:	155	Species:	Drosophila melanogaster
Sequence 2:	XP_005244786.2	Gene:	CALML6 / 163688	HGNCID:	24193	Length:	203	Species:	Homo sapiens

Alignment Length:	153	Identity:	53/153 - (34%)
Similarity:	83/153 - (54%)	Gaps:	2/153 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 NIDEDLTPEQIAVLQKAFNSFDHQKTGSIPTEMVADILRLMGQPFDRQILDELIDEVDEDKSGRL 67
            ::.|.|:.|||...:..|..||.:..|.:.|..:..::.|:|....:..|..:..:||.|..|..
Human    47 DMTERLSAEQIKEYKGVFEMFDEEGNGEVKTGELEWLMSLLGINPTKSELASMAKDVDRDNKGFF 111

  Fly    68 EFEEFVQLAAKFIVEEDDEAMQKELREAFRLYDKQGNGYIPTSCLKEILKELDDQLTEQELDIMI 132
            ..:.|  ||...:..|..:..:.|||.|||::||:|.|||..:.||.:|....:.|.|.|.:.|:
Human   112 NCDGF--LALMGVYHEKAQNQESELRAAFRVFDKEGKGYIDWNTLKYVLMNAGEPLNEVEAEQMM 174

  Fly   133 EEIDSDGSGTVDFDEFMEMMTGE 155
            :|.|.||..|:|::||:.|||||
Human   175 KEADKDGDRTIDYEEFVAMMTGE 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TpnC47D	NP_001286310.1	FRQ1	8..155	CDD:227455	50/146 (34%)
CALML6	XP_005244786.2	PTZ00184	48..195	CDD:185504	49/148 (33%)
		EFh	59..120	CDD:238008	15/62 (24%)
		EFh	133..195	CDD:238008	28/61 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001548
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23050
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	4	3.970