DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cpr47Ee and ep300

DIOPT Version :9

Sequence 1:	NP_610659.1	Gene:	Cpr47Ee / 36193	FlyBaseID:	FBgn0033602	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	XP_004913855.2	Gene:	ep300 / 734023	XenbaseID:	XB-GENE-482293	Length:	2492	Species:	Xenopus tropicalis

Alignment Length:	401	Identity:	102/401 - (25%)
Similarity:	133/401 - (33%)	Gaps:	158/401 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 RPQVPPLQPLQQQANPFQRRQPNPVQG--------QGLFPGQRNPLNPLAPPLTGAALQNPYTRY 96
            ||.:.|.|  .|..||.|....||.||        .|:.||.:.|.....||.|..  |.|:.:.
Frog  2002 RPMMNPHQ--MQPMNPMQPMGMNPQQGPRGQVHMESGIGPGMQQPQQQQQPPPTQP--QPPWVQS 2062

  Fly    97 NQYQQQNYVPITAYQNELNLDGSFSYGYSSADGTTAQAQGYVKNLGYGEGV-----EAQVIQGSY 156
            ...|.|:..|                |...:...:...||...|:....|:     .:|..|||.
Frog  2063 GLPQSQSMQP----------------GMQRSPIMSVPQQGQPMNMNPQSGIGQVPGASQTKQGSL 2111

  Fly   157 SYTSPEGTPITVR--------------------------------YIADENGFRAEGTG-IPSSP 188
            ...:.:....|:|                                |.:.:|   |:..| :|..|
Frog  2112 PQAALQNLLRTLRSPSSPMQQQQVLNILHSNPQLLAAFIKQRAAKYASSQN---AQAAGNVPGMP 2173

  Fly   189 -----QYFAGAQPYQQGLLNPNLNPYQTPFRQLPPPLPNAPFRPQLPGQQPLTPLQQQQQQQQQQ 248
                 |....:.|..||     :||.|.     ..|.|..|.:||.|.|||         .||..
Frog  2174 AQAGLQQVVHSNPGMQG-----MNPMQA-----IGPRPGMPQQPQAPQQQP---------PQQSP 2219

  Fly   249 LQQQ--RGFQQQQQP---NSGQYQPEQPFNQLHSGNLPGQYAGQFGQQSFGSNLTAQQAQQQQNL 308
            |.||  .|...|.||   |.|...|:  |.::                    .|..||..|||
Frog  2220 LPQQAMAGINPQGQPLNINPGGISPQ--FREI--------------------ILRRQQIMQQQ-- 2260

  Fly   309 NQQQQQQQQQQQQQQQQQKEQ----------------------QNEQQQQAL------------- 338
             |||||||||||||||||::|                      |.:||||..
Frog  2261 -QQQQQQQQQQQQQQQQQQQQGAGPGMVNHNQFQQHQVMSGYTQQQQQQQRFQHHIQMQQGSMGQ 2324

  Fly   339 ITQQLRGRPNN 349
            ::|..:|.|.:
Frog  2325 MSQMPQGMPGD 2335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cpr47Ee	NP_610659.1	Chitin_bind_4	120..177	CDD:278791	13/93 (14%)
ep300	XP_004913855.2	zf-TAZ	347..414	CDD:396624
		KIX	563..643	CDD:366953
		Med15	<650..>877	CDD:312941
		PHA03247	<777..982	CDD:223021
		Bromo_cbp_like	1080..1194	CDD:99927
		RING_CBP-p300	1206..1288	CDD:276805
		PHD_p300	1289..1323	CDD:277116
		HAT_KAT11	1352..1658	CDD:400497
		ZZ_CBP	1714..1754	CDD:239077
		zf-TAZ	1781..1849	CDD:396624
		Med15	1954..>2451	CDD:312941	102/401 (25%)
		Creb_binding	2059..2161	CDD:401102	15/117 (13%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910