Protein Alignment CG13223 and Slc24a3

DIOPT Version :9

• Sequence 1: NP_610656.1
• Gene: CG13223 / 36190
• FlyBaseID: FBgn0033599
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_001343426.1
• Gene: Slc24a3 / 94249
• MGIID: 2137513
• Length: 645
• Species: Mus musculus
• Alignment Length: 589
• Identity: 114/589 - (19%)
• Similarity: 201/589 - (34%)
• Gaps: 195/589 - (33%)

  Fly    54 LITIYVFWMMQITIKNYFCPTLMVIADLLRMNESTAGVTVLAIANGSPDFFTAIASRVQTSKHSF 118
            |..:|:|:.:.|...::|.|:|..|.:.|.::|..||.|.:|..:.:|:.||::.....|.....
Mouse   114 LCAMYMFYALAIVCDDFFVPSLEKICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVG 178

  Fly   119 L-SCMSQAMFLHIFV-------AGLVILTKPFNMRANTYLRDFGFLFLNTVYMDYIHKRPKGISW 175
            : :.:..|:|..:.:       ||.|:....:.:     |||..:..|:.|.: .:....:.:||
Mouse   179 VGTIVGSAVFNILCIIGVCGLFAGQVVALSSWCL-----LRDSIYYTLSVVAL-IVFIYDEKVSW 237

  Fly   176 LAALPSAFIFVGYVVVAIVDQHLLIARIQKMEQRQL----NVAEALQLEELKPQKEMPLKRQEID 236
            ..:|....:::.|:|:...:     |.|.:..:|:.    |:...|            ....|||
Mouse   238 WESLVLVLMYLIYIVIMKYN-----ACIHQCFERRTKGAGNMVNGL------------ANNAEID 285

  Fly   237 RPSIGHGSRNKRIFRQFWN---TVAEFDKDRFHRGTFLVKL-YLIVKQPIDML-----LRILI-- 290
            ..|               |   ||....|..|||...::.: .|:...|..:.     |||:|
Mouse   286 DSS---------------NCDATVVLLKKANFHRKASVIMVDELLSAYPHQLSFSEAGLRIMITS 335

  Fly   291 ---PKVDMEAPQYGWSKLLFNIQVVLVPTYIAYIIVRGYSIAGLAVYMIALILMIPVATLI---- 348
               ||..:...    |::|.|.:..|:.:       |.|:.....|     .:.||:...:
Mouse   336 HFPPKTRLSMA----SRMLINERQRLINS-------RAYTNGESEV-----AIKIPIKHTVENGT 384

  Fly   349 ----------------FFLTRTDT---------------------------------PP------ 358
                            ..:..||.                                 ||
Mouse   385 GPSSAPDRGVNGTRRDDIVAETDNETENENEDNENNENDEEEEEDEDDDEGPYTPFDPPSGKLET 449

  Fly   359 IFFRFTSGVGFMAAV-------------FLI-FCLTT----EVNAMFFTMATI----LQVSQEFS 401
            :.:.||..:.|:...             |:: |..:|    ..:.|...|.||    |.:.....
Mouse   450 VKWAFTWPLSFVLYFTVPNCNKPHWEKWFMVTFASSTLWIAAFSYMMVWMVTIIGYTLGIPDVIM 514

  Fly   402 LATAICWALSSNDLVANLSLAHQGWPRMAMTATFSAPVFASFVFLALPLVVNSFVNAPGNIFPTE 466
            ..|.:....|..|.:|:|.:|.||...||::.:..:.||...:.|.||..:.:
Mouse   515 GITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPWALQT------------ 567

  Fly   467 GGFGETVCIFLEVGMGFSMLSVLTTNFK-LRRACGFLLVSYYIFFVGVLI---LLEK----GVIH 523
                      |.|..|    |.:..|.: |..:.|.||.|.::...||.:   .|:|    |.:.
Mouse   568 ----------LAVDYG----SYIRLNSRGLIYSVGLLLASVFVTVFGVHLNKWQLDKKLGCGCLF 618

  Fly   524 AYGV 527
            .|||
Mouse   619 LYGV 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13223	NP_610656.1	Na_Ca_ex	45..194	CDD:279963	33/147 (22%)
		Na_Ca_ex	365..516	CDD:279963	36/176 (20%)
Slc24a3	NP_001343426.1	Na_Ca_ex	<89..631	CDD:332332	114/589 (19%)
		Alpha-1	148..188		9/39 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	379..398		0/18 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	404..442		2/37 (5%)
		Alpha-2	520..551		9/30 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1775
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840