DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13223 and YDL206W

DIOPT Version :9

Sequence 1:	NP_610656.1	Gene:	CG13223 / 36190	FlyBaseID:	FBgn0033599	Length:	527	Species:	Drosophila melanogaster
Sequence 2:	NP_010075.1	Gene:	YDL206W / 851321	SGDID:	S000002365	Length:	762	Species:	Saccharomyces cerevisiae

Alignment Length:	273	Identity:	63/273 - (23%)
Similarity:	114/273 - (41%)	Gaps:	42/273 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   270 FLVKLYLIVKQPIDMLLRILIP----KVDMEAPQYGWSKLLFNIQVVLVPTYIAYIIVRGYSIAG 330
            |...|.|:|..|:.::|.:.||    :.|.:.|    ...|.|||::..|..:..:|...:|
Yeast   504 FFEFLSLLVTTPVSIILYLSIPSEISQTDHDLP----LSYLQNIQLIASPIILNQLITNNFS--- 561

  Fly   331 LAVYMIALILMIPVATLIFFLTRTDTPPIFFRFTSGVGFMAAVFL-IFCLTTEVNAMFFTMA--- 391
                ...|||.:.:|.|::|.|||    |..:|.|.:.|..|..| :.||:..|:.:..|:.
Yeast   562 ----FWLLILSLVIAILLYFKTRT----IPNKFNSDIIFTVAFLLSLACLSKAVHIIVVTLTHWI 618

  Fly   392 TILQVSQEFSLATAICWALSSNDLVANLSLAHQGWPRMAMTATFSAPVFASFVFLALPLVVNSFV 456
            .:..:|:.....|...|..|..|||:|::....|...:|:.|.|.:|:......:....::....
Yeast   619 NVFNISETILGLTIFTWGNSIGDLVSNITFVKIGVLEIAIGACFGSPLLYFLFGVGFDGIMIMLG 683

  Fly   457 NAPGNIFPTEGGFGETVCI----------FLEVGMG----FSMLSVL--TTNFKLRRACGFLLVS 505
            :..|.|.   .|....:.:          .:..|:|    |.:.:||  ..::|:.:.....|::
Yeast   684 DKTGKIV---SGRDSNILMHHIDFKVDKNLINTGVGILIAFLIFTVLIPLNDWKIDKKISIALLT 745

  Fly   506 YYIFFVGVLILLE 518
            .||....:.:.||
Yeast   746 LYIVVTCISVFLE 758

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13223	NP_610656.1	Na_Ca_ex	45..194	CDD:279963
CG13223	NP_610656.1	Na_Ca_ex	365..516	CDD:279963	33/170 (19%)
YDL206W	NP_010075.1	ECM27	28..>223	CDD:223604
YDL206W	NP_010075.1	ECM27	<543..757	CDD:223604	49/227 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344061
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000933
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101277
Panther	1	1.100	-	-	O	PTHR12266
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1775
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.770