DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13223 and CAX11

DIOPT Version :9

Sequence 1:	NP_610656.1	Gene:	CG13223 / 36190	FlyBaseID:	FBgn0033599	Length:	527	Species:	Drosophila melanogaster
Sequence 2:	NP_172370.3	Gene:	CAX11 / 837416	AraportID:	AT1G08960	Length:	546	Species:	Arabidopsis thaliana

Alignment Length:	520	Identity:	127/520 - (24%)
Similarity:	238/520 - (45%)	Gaps:	74/520 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 NMNLFNYLGWHYCKVDVRNSFNSFWSVLGMFLITIYVFWMMQITIKNYFCPTLMVIADLLRMNES 87
            |..:.||...|||   :.|. |.|:|:..:.|:.:..|:::..|.:.:|......:||.|.::.|
plant    71 NGGVINYFSLHYC---IFNE-NLFFSIPILSLLILLHFYILIKTAQTHFSTVTTKLADRLNLSPS 131

  Fly    88 TAGVTVLAIANGSPDFFTAIAS-RVQTSKHSFLSCMSQAMFLHIFVAGLV-ILTKPFNMRANTYL 150
            .|.||:||:.||:||.|.::|: |....:..|.:.:|...|:..||.|.| |...||.:.|.:::
plant   132 MAAVTLLALGNGAPDVFASVAALRGGQYRTGFGAILSAGTFVSAFVVGFVAIYAAPFPVDAASFV 196

  Fly   151 RDFGFLFLNTVYMDYIHKRPKGISWLAALPSAFIFVGYVVVAIVDQHLLIARIQKMEQRQLNVAE 215
            ||..|..:..:::.|::...:...|     .|..|||:.:       ..:..:..|: ...||.:
plant   197 RDVLFYLIAALFLFYVYLSGEIFVW-----QAIGFVGFYI-------FFVGFVFWMD-FGTNVEK 248

  Fly   216 ALQLEELKPQKEMPLKRQEIDRPSIGHGSRNKRIFRQFWNTVAEFDKDRFHRGTFLVKLYLIVKQ 280
            ...:.|  .:|:: |:.|:.:   |..||            :..:..::.|:.:.:.:||..:.:
plant   249 GKSISE--EEKDL-LRLQDCE---IAAGS------------LGSYKAEKEHQFSGIFRLYGTISR 295

  Fly   281 ----PIDMLLRILIPKVDMEAPQYGWSKLLFNIQVVLVPTYIAY----IIVRGYSIA------GL 331
                |:.:||.:.|||   .:|. .||:...:..:|..|..:.|    .:...:.|:      .|
plant   296 MWETPVSVLLNLTIPK---PSPS-EWSRFYRSANIVFCPFALLYTCNSFVQLNHPISFLFPNTHL 356

  Fly   332 AVYMIALILMIPVATLIFFL----TRTDTPPIFFRFTSGVGFMAAVFLIFCLTTEVNAMFFTMAT 392
            .::::.|.:...:|.|.|.:    .:|:..|:..     |.|:.:||.|..:..|:......:.|
plant   357 PLWLVVLFMTSSLAFLHFTVEKQPPKTEQLPVIV-----VAFIMSVFWISTIAGELLNCLAALGT 416

  Fly   393 ILQVSQEFSLATAICWALSSNDLVANLSLAHQGWPRMAMTATFSAPVFASFVFLALPLVVNSFVN 457
            :|::.......|.:.|..|..||||::::|..|.|.|||...|:.|:|...|.|...||:.:
plant   417 LLKLPPALLGLTVLAWGNSVGDLVADVAVAKAGRPAMAMAGCFAGPMFNMLVGLGSALVMQT--- 478

  Fly   458 APGNIFPTEGGFGETV-----CIFLEVGMGFSMLSVLTTNFKLRRACGFLLVSYYIFFVGVLILL 517
              .|::|.....|..|     .:||.:.:..|:|.:..:.|::.|..|..||..|:.|..|.:::
plant   479 --ANVYPDAYKLGFHVGIVIAFVFLLLSLMGSLLVITWSRFRVPRFWGICLVGLYVAFTFVSLII 541

Fly 518 517
plant 542 541

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13223	NP_610656.1	Na_Ca_ex	45..194	CDD:279963	42/150 (28%)
CG13223	NP_610656.1	Na_Ca_ex	365..516	CDD:279963	44/155 (28%)
CAX11	NP_172370.3	PLN03151	72..539	CDD:215604	126/515 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57812
OrthoDB	1	1.010	-	-		D478735at2759
OrthoFinder	1	1.000	-	-		FOG0000933
OrthoInspector	1	1.000	-	-		mtm1105
orthoMCL	1	0.900	-	-		OOG6_101277
Panther	1	1.100	-	-	O	PTHR12266
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.790