DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13223 and CAX7

DIOPT Version :9

Sequence 1:	NP_610656.1	Gene:	CG13223 / 36190	FlyBaseID:	FBgn0033599	Length:	527	Species:	Drosophila melanogaster
Sequence 2:	NP_197288.1	Gene:	CAX7 / 831654	AraportID:	AT5G17860	Length:	570	Species:	Arabidopsis thaliana

Alignment Length:	535	Identity:	130/535 - (24%)
Similarity:	250/535 - (46%)	Gaps:	58/535 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 KCKFVQTTPDCLINMNLFNYLGWHYCKVDVRNSFNSFWSVLGMFLITIY---VFWMMQITIKNYF 71
            ||.::::...| ......:||...:|      .|... .|||..:::.:   :|:::..|..:||
plant    68 KCSYIRSQSKC-GPQGYIDYLKIFFC------IFGQS-PVLGHLVLSAWLFVLFYLLGDTAASYF 124

  Fly    72 CPTLMVIADLLRMNESTAGVTVLAIANGSPDFFTAIASRVQTSKHSF--LSCMSQAMFLHIFVAG 134
            ||:|..::.:|:::.:.||||:|::.||:||.|:::.|..:::...|  .|.:..|.|:..||.|
plant   125 CPSLDSLSKVLKLSPTMAGVTLLSLGNGAPDLFSSVVSFTRSNNGDFGLNSILGGAFFVSSFVVG 189

  Fly   135 ---LVILTKPFNMRANTYLRDFGFLFLNTVYMDYIHKRPKGISWLAA--LPSAFIFVGYVVVAIV 194
               ::|.::...:..|:::||..||.:....:..|....|...|:|.  |....::||::.|:
plant   190 TICVLIGSRDVAIDRNSFIRDVVFLLVALCCLGLIIFIGKVTIWVALCYLSIYLLYVGFLSVS-- 252

  Fly   195 DQHLLIARIQKMEQRQLNVAEALQLEELKPQKEMPLKRQEIDRPSIGHGSRNKRIFRQFWNTVAE 259
              | ...|.::|..:.|...|.|               .|:....:|:.:..|....:  .|..|
plant   253 --H-FFDRKKRMSDQILRSREDL---------------AEMGVSLLGYIAEEKLALPE--KTTQE 297

  Fly   260 F-----DKDRFHRGTFLVKLYLIVKQPIDMLLRILIPKVDMEAPQYGWSKLLFNIQVVLVPTYIA 319
            |     |..:.||..|.| |..|:..|:.:..|:.||.|..|.    |||....:...:.|..:.
plant   298 FKIVFEDSPKRHRSCFSV-LVSIIGLPLYLPRRLTIPVVCEEK----WSKPCAVVSTAIAPVLLT 357

  Fly   320 YIIVRGYSIA--GLAVYMIALILMIPVATLIFFLTRTDTPPIFFRFTSGV-GFMAAVFLIFCLTT 381
            .:....||.:  .|.:|:|:..:.:.|..|.:..|....||..|.....: ||..:|...:.:..
plant   358 ELYCSHYSGSQRNLILYIISGSIGLIVGILAYLTTEKSHPPKKFSLVWLLGGFTMSVTWTYMIAQ 422

  Fly   382 EVNAMFFTMATILQVSQEFSLATAICWALSSNDLVANLSLAHQG---WPRMAMTATFSAPVFASF 443
            |:.::..::..|..:|......|.:.|..|..||:||:::|..|   ..::|::..::.|:|.:.
plant   423 ELVSLLISLGNIFGISPSVLGLTVLAWGNSLGDLIANVTVAFHGGNDGAQIALSGCYAGPLFNTV 487

  Fly   444 VFLALPLVVNSFVNAPG-NIFPTEGGFGETVCIFLEVGMGFSMLSVLTTNFKLRRACGFLLVSYY 507
            :.|.:|||::|....|| .|.|::....||:. ||.||:.::::.:.....:|.:..|..|::.|
plant   488 IGLGVPLVISSLAEYPGVYIIPSDNSLLETLG-FLMVGLLWALVIMPKKKMRLDKLVGGGLLAIY 551

  Fly   508 IFFVGVLILLEKGVI 522
            :.|:.:.:....||:
plant   552 LCFLSLRLARVFGVL 566

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13223	NP_610656.1	Na_Ca_ex	45..194	CDD:279963	43/158 (27%)
CG13223	NP_610656.1	Na_Ca_ex	365..516	CDD:279963	38/155 (25%)
CAX7	NP_197288.1	PLN03151	30..566	CDD:215604	129/533 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	62	1.000	Domainoid score	I3746
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	131	1.000	Inparanoid score	I1872
OMA	1	1.010	-	-		QHG57812
OrthoDB	1	1.010	-	-		D478735at2759
OrthoFinder	1	1.000	-	-		FOG0000933
OrthoInspector	1	1.000	-	-		mtm1105
orthoMCL	1	0.900	-	-		OOG6_101277
Panther	1	1.100	-	-	O	PTHR12266
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.840