DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13223 and AT5G17850

DIOPT Version :9

Sequence 1:	NP_610656.1	Gene:	CG13223 / 36190	FlyBaseID:	FBgn0033599	Length:	527	Species:	Drosophila melanogaster
Sequence 2:	NP_001318589.1	Gene:	AT5G17850 / 831653	AraportID:	AT5G17850	Length:	559	Species:	Arabidopsis thaliana

Alignment Length:	558	Identity:	127/558 - (22%)
Similarity:	243/558 - (43%)	Gaps:	88/558 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 HDLLESQKCKFVQTTPDCLINMNLFNYLGWHYCKVDVRNSFNSFWSVLGMFLITIY---VFWMMQ 64
            ||.  ..||.::::...| .:...|:||.:.||      :|..| .:||.||:.::   :|:::.
plant    53 HDY--KSKCAYLKSIDPC-ASQGFFDYLSFLYC------NFEGF-PILGQFLLFLWLLLLFYLLG 107

  Fly    65 ITIKNYFCPTLMVIADLLRMNESTAGVTVLAIANGSPDFFTAIASRVQTSKHSF----LSCMSQA 125
            .|...|||.:|..::.||.::.:.||||:|::.||:||.|.::.|.:..||.::    .:.:..:
plant   108 HTASEYFCSSLESLSKLLNLSPTVAGVTLLSLGNGAPDLFASLVSFMGESKGTYDVGLNTVVGGS 172

  Fly   126 MFLHIFVAGLVILT---KPFNMRANTYLRD-------FGFLFLNTVYMDYIHKRPKGISWLAALP 180
            .|:...|.|::.::   :...:....::||       .|.|.|..||        ..|::..||.
plant   173 GFVTCVVVGIISISLHKRRVRIERAAFIRDICFFCAAIGSLALILVY--------GKINFWGALG 229

  Fly   181 SAFIFVGYVVVAIV------DQHLLIARIQKMEQRQLNVAEALQLEELKPQ---KEMPLKRQEID 236
            ...::..||...::      ||.                ||: .||.:..:   .|..|:|..::
plant   230 FCSLYAVYVAFVVLSWRFGGDQG----------------AES-DLESIHKRGSLSEPILQRDGLE 277

  Fly   237 RPSIGHGSRNKRIFRQFWNTVAEFDKDRFHRGTFLVKLYLI--VKQPIDMLLRILIPKVDMEAPQ 299
            ....|..:...:|          .|.|..|:..:..|..:|  :..|:::...:.||.|..:.
plant   278 EIEDGVVNGEHQI----------VDDDDDHQRYYYWKRLVIWAITLPLNLPRILTIPVVSEDK-- 330

  Fly   300 YGWSKLLFNIQVVLVPTYIAYI---IVRGYSIAGLAVYMIALILMIPVATLIFFLTRTDTPP--I 359
              |||.|....|...|..::::   ..:..|.....||:|..::.|.:..:....|:..|||  .
plant   331 --WSKPLAVASVTFAPVLLSFLWNWKRKPTSFEAGVVYLIGCLIGIALGFIAGATTKKLTPPKKW 393

  Fly   360 FFRFTSGVGFMAAVFLIFCLTTEVNAMFFTMATILQVSQEFSLATAICWALSSNDLVANLSLA-H 423
            ...:.:| ||:.::...:....|:.|:..::..|..||......|.:.|..|..||:.||::| |
plant   394 LLPWLAG-GFVMSMTWSYISAQELVALLTSLGYIFGVSPSILGLTVLAWGNSIGDLITNLTMALH 457

  Fly   424 QG--WPRMAMTATFSAPVFASFVFLALPLVVNSFVNAPGNI-FPTEGGFGETVCIFLEVGMGFSM 485
            .|  ..::|::..::.|:|.:...|.:.||..::...|.:| ..|:....|::. ||..|:.:|.
plant   458 DGNEGAQVAVSGCYAGPIFNTLFALGISLVGCAWEAYPLSIVIKTDPRLLESLG-FLVAGLVWSF 521

  Fly   486 LSVLTTNFKLRRACGFLLVSYYIFFVGVLILLEKGVIH 523
            |.:.:...:|....|..|:..|:..:.:.|:...|..|
plant   522 LVLFSNRMRLGGVMGIGLLVIYLASLSLRIMQTVGDAH 559

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13223	NP_610656.1	Na_Ca_ex	45..194	CDD:279963	41/165 (25%)
CG13223	NP_610656.1	Na_Ca_ex	365..516	CDD:279963	37/154 (24%)
AT5G17850	NP_001318589.1	PLN03151	34..556	CDD:215604	125/553 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	62	1.000	Domainoid score	I3746
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	131	1.000	Inparanoid score	I1872
OMA	1	1.010	-	-		QHG57812
OrthoDB	1	1.010	-	-		D478735at2759
OrthoFinder	1	1.000	-	-		FOG0000933
OrthoInspector	1	1.000	-	-		mtm1105
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12266
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.940