DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13223 and CAX9

DIOPT Version :9

Sequence 1:	NP_610656.1	Gene:	CG13223 / 36190	FlyBaseID:	FBgn0033599	Length:	527	Species:	Drosophila melanogaster
Sequence 2:	NP_566474.1	Gene:	CAX9 / 820622	AraportID:	AT3G14070	Length:	643	Species:	Arabidopsis thaliana

Alignment Length:	576	Identity:	130/576 - (22%)
Similarity:	249/576 - (43%)	Gaps:	99/576 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 SQKCKFVQTTPDCLINMNLFNYLGWHYCKVDVRNSFNSFWSVLGMFLITIY---VFWMMQITIKN 69
            :.:|:|::..|.|..: ..|:||.:.||      |...| |:||..::.::   :|:::..|..:
plant   102 ADQCEFLKANPICSPD-GFFDYLSFFYC------SCRDF-SILGYMMLGVWLVALFYLLGNTAAD 158

  Fly    70 YFCPTLMVIADLLRMNESTAGVTVLAIANGSPDFFTAIASRVQTSKH--SFLSCMSQAMFLHIFV 132
            |||.:|..::.|||:..:.||||:|.:.||:||.|.:||:.|.|.|.  ...|.:..|:|:...|
plant   159 YFCCSLEKLSKLLRLPPTVAGVTLLPLGNGAPDVFASIAAFVGTDKGEVGLNSVLGGAVFVTSVV 223

  Fly   133 AGLV---ILTKPFNMRANTYLRDFGFLFLNTVYMDYIHKRPKGISWLAALPSAFIFVGYVVVAIV 194
            .|:|   :..|...:..|.::||..|...:.|.:..|        .:....:..|.:.:|.:.:|
plant   224 VGIVSLCVADKEVKIDKNCFIRDLSFFLFSLVSLLVI--------LMVGRVTVRIAIAFVSIYVV 280

  Fly   195 DQHLLIARIQKMEQRQLNVAEALQLEELKPQKEMPLKRQEIDRPSIGHG---------------- 243
            ...|:.|.:...:.     |:..:||.|.|...|   :..:..||:|..
plant   281 YAFLVAANVILRKH-----AKRFKLEALTPLLPM---QGSVFSPSVGEDMPMNTPLIETETEDGP 337

  Fly   244 -----------SRNKRIFRQFWNTVAEFDKDRFHRG----------TFLVKLYLIVKQPIDMLLR 287
                       :.|..|:...:..|:..|:||...|          :...|...:::.|:.:..|
plant   338 PRLQSLPQWMWASNVAIYSNHFAKVSVHDEDRPPWGWIDDTAEVESSSCTKFTSLLEIPLTIPRR 402

  Fly   288 ILIPKVDMEAPQYGWSKLLFNIQVVLVPTYIAYIIVRGYSIA----GLAVYMIALILMIPVATLI 348
            :.||.|:.:.    |||......|.|.|..:|.:......::    |:| |..::::...:..|.
plant   403 LTIPSVEEDT----WSKTYAVASVSLAPVLLASLWSSQDDVSLQACGVA-YFFSVVIGSTLGFLA 462

  Fly   349 FFLTRTDTPP--IFFRFTSGVGFMAAVFLIFCLTTEVNAMFFTMATILQVSQEFSLATAICWALS 411
            :..|..|.||  ....:..| ||:.::...:.:..|:.|:..|...|..::......|.:.|..|
plant   463 YKNTEPDHPPRRFLIPWVLG-GFIMSIVWFYMIANELVALLVTFGEIYGINPSILALTVLAWGNS 526

  Fly   412 SNDLVANLSLAHQGWP--RMAMTATFSAPVFASFVFLALPLVVNSFVNAPG--------NIFPTE 466
            ..|||:|::|...|..  ::|::..::.|:|.:.|.|.:.::..::..:|.        ::|.|.
plant   527 MGDLVSNIALTMNGGDGVQIALSGCYAGPMFNTLVGLGMSMLFGAWSKSPDTYMLPEDKSLFYTL 591

  Fly   467 GGFGETVCIFLEVGMGFSMLSVLTTNFKLRRACGFLLVSYYIFFVGVLILLEKGVI 522
            |        ||.:|:.::|:.:...:.:..|..|..|::.|:.||...:....|.|
plant   592 G--------FLVLGLVWAMVILPRNDMQPSRTLGVGLIAIYLIFVTFRLSCAMGFI 639

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13223	NP_610656.1	Na_Ca_ex	45..194	CDD:279963	43/156 (28%)
CG13223	NP_610656.1	Na_Ca_ex	365..516	CDD:279963	35/160 (22%)
CAX9	NP_566474.1	PLN03151	1..643	CDD:215604	130/576 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	62	1.000	Domainoid score	I3746
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57812
OrthoDB	1	1.010	-	-		D478735at2759
OrthoFinder	1	1.000	-	-		FOG0000933
OrthoInspector	1	1.000	-	-		mtm1105
orthoMCL	1	0.900	-	-		OOG6_101277
Panther	1	1.100	-	-	O	PTHR12266
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.790