DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13223 and CG34162

DIOPT Version :9

Sequence 1:	NP_610656.1	Gene:	CG13223 / 36190	FlyBaseID:	FBgn0033599	Length:	527	Species:	Drosophila melanogaster
Sequence 2:	NP_001097149.2	Gene:	CG34162 / 5740392	FlyBaseID:	FBgn0085191	Length:	535	Species:	Drosophila melanogaster

Alignment Length:	546	Identity:	111/546 - (20%)
Similarity:	216/546 - (39%)	Gaps:	99/546 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 SQKCKFVQTTPDCLINMNLFNYLGWHYCKVDVRNSFNSFWSVLGMFLITIYVFWMMQITIKNYFC 72
            :|.|...::|..|...:.|.|||...:|...:...  |.:.::..||:.:::..:..:| |.:|.
  Fly    23 NQTCGLARSTLSCGSLVYLINYLDICFCVFKLPTM--SIYGLISAFLLMVHLSVLFMVT-KYFFV 84

  Fly    73 PTLMVIADLLRMNESTAGVTVLAIANGSPDFFTAIAS---RVQTSKHSFLSCMSQAMFL------ 128
            |.|..:.:...|  :..|.:.|..   .|.||.:..:   .:...:.....|:|...|.
  Fly    85 PNLATLIEFAPM--TMFGSSFLLF---GPTFFVSYYNSFWEICNPRKPESICLSPLQFAKIMGDI 144

  Fly   129 --HIFVAGLVILTKPFNMRANTYLRDFGFLFLNTVYMDYIHKRPKGISWLAA-------LPSAFI 184
              :|.:..:||..:.:.:...|:.....|:....||:..:.|:...:..:.|       ..:.|:
  Fly   145 LRYIVIGFMVICAQGYRVDGITFWSCLSFILTGMVYLYIVIKKSYNVYLIVADLYSIKFRVTVFL 209

  Fly   185 FVGYVVVAIVDQHLLIARIQ----KMEQRQLNVAEALQLEEL--KPQKEMPLKRQEIDRPSIGHG 243
            :. :::|.:|...:..|..|    |.:|.|.|..|....:|:  |.||:|...|:||...:: :|
  Fly   210 YT-FLMVLLVIFVVSYANFQRSKVKSKQTQENFLEMDSGDEILGKYQKQMEFSRREIWLKAV-NG 272

  Fly   244 SRNKRIFRQFWNTVAEFDKDRFHRGTFLVKLYLIVKQPIDMLLRILIPKVDMEAPQYGWSKL--- 305
            .||          :|:.:           .:|.|...|...:|...||.:..:....||:|.
  Fly   273 YRN----------MADSN-----------VIYRIAMIPSYFVLANFIPVISNDRALIGWNKYTSC 316

  Fly   306 --LFNIQVVLVPTYIAYIIVRGY-SIAGLAVYMIALILMIPVATLIFFLTRTDTPPIFFRFTSGV 367
              ||.:.::.:|        .|: :::.|.:::....|.|    |.|..|.:...|......:.:
  Fly   317 LGLFFLPIICLP--------HGFKAVSWLIMFLTCWTLSI----LTFISTHSLRRPNNIWIFALL 369

  Fly   368 GFMAAVFLIFCLTTEVNAMFFTMATILQVSQEFSL---ATAICW----ALSSNDLVANLSLAHQG 425
            |.:.:...|..|:.|:..:.:.     .:|.:|.:   .||:.:    .:.|..:|.......:.
  Fly   370 GLIVSSVFINLLSREIENIIYQ-----YISMQFDVMPDVTALVYFGLGEMLSESIVVRCLQQRKM 429

  Fly   426 WPRMAMTATF----SAPVFASFVFLALPLV-VNSFVNAPGNIFPTEGGFGETVCIFLEVGMGFSM 485
            |     .|||    |...:|  :|||.||: .....|...:|..|..  .||...|:.:.:...:
  Fly   430 W-----DATFGVVMSLVTYA--IFLAFPLLFFQGCYNNKCSIMVTSS--TETTIHFIFLVLSTCL 485

  Fly   486 LSVLTTNFKLRRACGFLLVSYYIFFV 511
            |.|..:.::.|.:..|.|:...:|:|
  Fly   486 LHVSLSGYEFRISLLFYLLVLTVFYV 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13223	NP_610656.1	Na_Ca_ex	45..194	CDD:279963	28/166 (17%)
CG13223	NP_610656.1	Na_Ca_ex	365..516	CDD:279963	34/159 (21%)
CG34162	NP_001097149.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810