DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13223 and slc8b1

DIOPT Version :9

Sequence 1:	NP_610656.1	Gene:	CG13223 / 36190	FlyBaseID:	FBgn0033599	Length:	527	Species:	Drosophila melanogaster
Sequence 2:	NP_001017082.1	Gene:	slc8b1 / 549836	XenbaseID:	XB-GENE-957176	Length:	238	Species:	Xenopus tropicalis

Alignment Length:	192	Identity:	59/192 - (30%)
Similarity:	103/192 - (53%)	Gaps:	12/192 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 SQKCKFVQTTPDCLINMNLFNYLGWHYCKVDVRNSFNSFWSVLGMFLIT---IYVFWMMQITIKN 69
            |.:|.|.:|||||.:.....|||...:|      ||......|.:||.|   :|:|.::.:|.:.
Frog    51 SLRCNFTRTTPDCSVGDGYINYLDGAFC------SFLPSLFPLAIFLYTLWLLYLFIILAVTAEK 109

  Fly    70 YFCPTLMVIADLLRMNESTAGVTVLAIANGSPDFFTAIA--SRVQTSKHSFLSCMSQAMFLHIFV 132
            :|||.|..|:.:||::.:.||||.||..||:||.|:|:|  |..:|:..:..:.....:|:...|
Frog   110 FFCPNLSAISRILRLSHNVAGVTFLAFGNGAPDVFSAVAAFSDSRTAGLAIGALFGAGVFVTTVV 174

  Fly   133 AGLVILTKPFNMRANTYLRDFGFLFLNTVYMDYIHKRPKGISWLAALPSAFIFVGYVVVAIV 194
            ||.:.:.|||...:..:|||..| :::.:::.:.......::...||....:::.||.|.::
Frog   175 AGGITIVKPFTAASRPFLRDIVF-YISAIFLTFFILYQGFVTLAEALVYLLLYLVYVFVVVI 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13223	NP_610656.1	Na_Ca_ex	45..194	CDD:279963	45/153 (29%)
CG13223	NP_610656.1	Na_Ca_ex	365..516	CDD:279963
slc8b1	NP_001017082.1	Na_Ca_ex	94..219	CDD:279963	36/125 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	77	1.000	Domainoid score	I8733
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D257493at33208
OrthoFinder	1	1.000	-	-		FOG0000933
OrthoInspector	1	1.000	-	-		otm47675
Panther	1	1.100	-	-	O	PTHR12266
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.110