DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13223 and CG12061

DIOPT Version :9

Sequence 1:	NP_610656.1	Gene:	CG13223 / 36190	FlyBaseID:	FBgn0033599	Length:	527	Species:	Drosophila melanogaster
Sequence 2:	NP_001104467.2	Gene:	CG12061 / 3354990	FlyBaseID:	FBgn0040031	Length:	441	Species:	Drosophila melanogaster

Alignment Length:	526	Identity:	94/526 - (17%)
Similarity:	182/526 - (34%)	Gaps:	133/526 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 HDL---LESQKCKFVQTTPDCLINMNLFNYLGWHYCKVDVRNSFNSFWSVLGMFLITIYVFWMMQ 64
            ||:   ::::.|    |.|..:...||.....|              .:::...|:::|:|.::.
  Fly    26 HDMRYDIDARNC----TLPAIVEFPNLMRQKSW--------------IAIVVSTLVSMYLFVILA 72

  Fly    65 ITIKNYFCPTLMVIADLLRMNESTAGVTVLAIANGSPDFFTAIASRVQTSKHSFL-SCMSQAMFL 128
            |...:|..|.:..:...|||....||.|.||.:..:|:.|........|:....| :.:..::|.
  Fly    73 IVCDDYLVPAMERLCYTLRMTYDVAGATFLAASTSAPELFVNFVGTFVTNGDIGLGTIVGSSVFN 137

  Fly   129 HIFVAGLV-ILTKPFNMRANTYLRDFGFLFLNTVYMDYIHKRPKGISWLAALPSAFIFVGYVVVA 192
            .:.:||:. |.|:|..:......||..:..:....:.|: .....:.|..|.....:::.||:..
  Fly   138 ILVIAGVCGIFTQPTKLDWWPVTRDTAWYLIAIASLTYV-LWDSLVMWYEAFALLLLYISYVIQL 201

  Fly   193 IVDQHLLIARIQKMEQRQLNVAEALQLEELKPQKEMPLKRQEIDRPSIGHGSRNKRIFRQFWNTV 257
            ..|:     |||.:.:.:...:|.|. |:...::|.|||           |.|:
  Fly   202 SFDR-----RIQNLVRHEHAESELLD-EDPMTREEEPLK-----------GFRD----------- 238

  Fly   258 AEFDKDRFHRGTFLVKLYLIVKQPIDMLLRILIPKVDMEAPQYGWSKLLFNIQVVLVPTYIAYII 322
                             ::..|           ||.:....|:.|..:.:..:::|..|
  Fly   239 -----------------HVCAK-----------PKTEYNFYQWTWWAIKYPAELMLACT------ 269

  Fly   323 VRGYSIAGLAVYMIALILMIPVATLIFFLTRTDTPPIFFRFTSGVGFMAAVFLIFCLTTEVNAMF 387
                               :|.|..||||:                 |.:..|...|.:.:...|
  Fly   270 -------------------VPSARSIFFLS-----------------MISAILWISLISYLLTWF 298

  Fly   388 FT-MATILQVSQEFSLATAICWALSSNDLVANLSLAHQGWPRMAMTATFSAPVFASFVFLALPLV 451
            .| :...|.:.......|.:....|..::.::..::.:|:..||:.....:..|...|.|.||.:
  Fly   299 LTILGYNLNIPDAIMGLTVLAAGTSVPEVASSYIVSKKGYGSMAICNAIGSNTFDILVCLGLPWL 363

  Fly   452 VNSFVNAPGNIFPTEGGFGET----VCIFLEVGMGFSMLSVLTTNFKLRRACGFLLVSYYIFFVG 512
            :...      |:..:.....|    ....|.|......|.:|...|.:.:..|:|.:.:|..|:.
  Fly   364 LKIL------IYQQKIDIDSTALTITTAMLVVTAAVLYLGLLARRFVMGKTVGYLSIIFYALFLI 422

  Fly   513 VLILLE 518
            :...||
  Fly   423 IACTLE 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13223	NP_610656.1	Na_Ca_ex	45..194	CDD:279963	31/150 (21%)
CG13223	NP_610656.1	Na_Ca_ex	365..516	CDD:279963	27/155 (17%)
CG12061	NP_001104467.2	TIGR00367	61..422	CDD:273039	84/465 (18%)
		Na_Ca_ex	62..199	CDD:279963	30/137 (22%)
		Na_Ca_ex	276..424	CDD:279963	31/170 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810