Protein Alignment CG13223 and Slc24a4

DIOPT Version :9

• Sequence 1: NP_610656.1
• Gene: CG13223 / 36190
• FlyBaseID: FBgn0033599
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_742164.2
• Gene: Slc24a4 / 238384
• MGIID: 2447362
• Length: 622
• Species: Mus musculus
• Alignment Length: 613
• Identity: 116/613 - (18%)
• Similarity: 196/613 - (31%)
• Gaps: 241/613 - (39%)

  Fly    48 SVLGMFLITIYVFWMMQITIKNYFCPTLMVIADLLRMNESTAGVTVLAIANGSPDFF-------- 104
            :||...|..:|:|:.:.|...::|.|:|..|.:.|.::|..||.|.:|..:.:|:.|
Mouse    99 AVLLHILGALYMFYALAIVCDDFFVPSLEKICEKLHLSEDVAGATFMAAGSSTPELFASVIGVFI 163

  Fly   105 --------TAIASRV--------------------------QTSKHSFLSCMSQAMFLH----IF 131
                    |.:.|.|                          :.|.:..||.:....|::    ::
Mouse   164 THGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVRLTWWAVCRDSVYYTLSVIVLIAFIYDEEIVW 228

  Fly   132 VAGLV--------ILTKPFNMRANTY-----------------LRDFGFLFLNTVYMD------- 164
            ..|||        ||...:||:..|:                 |.|...|: :..|.|
Mouse   229 WEGLVLIILYVFYILIMKYNMKMQTFFTTKQKSIANGNPVSNELEDGNDLY-DGSYDDPSVPLLG 292

  Fly   165 -YIHKRPKGIS-------WLAALPSAFIF--VGYVV-----------------VAIVDQHLLI-- 200
             ...|.|.|.:       .|::.|..|.|  .|..:                 :.|.::..||
Mouse   293 QVKEKPPYGKTPVVMVDEILSSSPPKFTFPEAGLRIMITNKFGPRTRLRMASRIIINERQRLINS 357

  Fly   201 -----------ARIQKMEQRQL---NVAEALQLEELKPQKEMPLKRQEIDRPSIGHGSRNKRIFR 251
                       .|.:.||...:   |..:..|.:|.:|..:.|....|         |.......
Mouse   358 ANGVNSKPLQNGRHENMENGNVPVENPEDPQQGQEQQPPPQPPPPEPE---------SVETVFLS 413

  Fly   252 QFWNTVAEFDKDRFHRGTFLVKLYLIVKQPIDMLLRILIPKVDMEAPQYGWSKLLFNIQVVLVPT 316
            .|....|:.||.::           :...|:..||.:.||  :...|:  |.|..    :|...|
Mouse   414 PFSMPEAKGDKAKW-----------VFTWPLIFLLCVTIP--NCSKPR--WEKFF----MVTFIT 459

  Fly   317 YIAYIIVRGYSIAGLAVYMIALI---LMIPVATLIFFLTRTDTPPIFFRFTSGVGFMAAVFLIFC 378
            ...:|.|..|    |.|:::.:|   |.||...:                  |:.|:||
Mouse   460 ATLWIAVFSY----LMVWLVTIIGYTLGIPDVIM------------------GITFLAA------ 496

  Fly   379 LTTEVNAMFFTMATILQVSQEFSLATAICWALSSNDLVANLSLAHQGWPRMAMTATFSAPVFASF 443
                                          ..|..|.:|:|.:|.||...||::.|..:.||...
Mouse   497 ------------------------------GTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDIL 531

  Fly   444 VFLALP-----LVVNSFVNAPGNIFPTEGGFGETV----------CIFLEVGMGFSMLSVLTTNF 493
            |.|.:|     :|:|               :|.||          .:.|...:..::|.:....:
Mouse   532 VGLGIPWGLQTMVIN---------------YGSTVKINSRGLVYSVVLLLGSVALTVLGIHLNKW 581

  Fly   494 KLRRACGFLLVSYYIFFVGVLILLEKGV 521
            :|.|..|..::..|..|:...|::|..|
Mouse   582 RLDRKLGIYVLVLYAVFLCFSIMIEFNV 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13223	NP_610656.1	Na_Ca_ex	45..194	CDD:279963	46/250 (18%)
		Na_Ca_ex	365..516	CDD:279963	31/165 (19%)
Slc24a4	NP_742164.2	Na_Ca_ex	<80..606	CDD:332332	114/608 (19%)
		Alpha-1	139..179		8/39 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	358..408		10/58 (17%)
		Alpha-2	495..526		12/66 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1775
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840