Protein Alignment CG13223 and ncx-6

DIOPT Version :9

• Sequence 1: NP_610656.1
• Gene: CG13223 / 36190
• FlyBaseID: FBgn0033599
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_499146.2
• Gene: ncx-6 / 182354
• WormBaseID: WBGene00003571
• Length: 590
• Species: Caenorhabditis elegans
• Alignment Length: 570
• Identity: 137/570 - (24%)
• Similarity: 250/570 - (43%)
• Gaps: 106/570 - (18%)

  Fly     8 SQKCKFVQTTPDCLINMNLFNYLGW-HYCKVDVRNSFNSFWSVLGMFLITIYVFWMMQITIKNYF 71
            :|.|::|:...|   |.....|:.| .|.:.....:......:.|:..:.: :|.|:.....::|
 Worm    62 TQVCEYVKCNDD---NCEGGGYVLWTRYVECASSPAVRIILIITGVIYMLV-LFIMVSSAADDFF 122

  Fly    72 CPTLMVIADLLRMNESTAGVTVLAIANGSPDFFTAIASRVQ--TSKHSFL--SCMSQAMFLHIFV 132
            .|::..|...||::||.||||.:|..||:||.|.||||.:.  |.|....  ......:|:...|
 Worm   123 SPSISSIVAHLRISESVAGVTFMAFGNGAPDVFGAIASVLSSPTPKADLALGELFGAGLFVTTMV 187

  Fly   133 AGLVILTKPFNMRANTYLRD-------FGFLFLNTVYMDYIHKRPKGISWLAALPSAF--IFVGY 188
            ..:.|.|:||.....:.:||       ..||....||.|::.      .|   :|..|  :::.|
 Worm   188 LAVTIFTRPFKAEVFSSIRDIAFYLVALAFLAFCFVYYDHVE------IW---MPITFLGVYLIY 243

  Fly   189 VVVAIVDQHLLIARIQKMEQR--QLNVAEALQLEE------------------LKPQKEM----P 229
            |...|:.| :|..|.:|.|::  ::...:...||:                  :|.:.|:    |
 Worm   244 VCTVILSQ-ILHNRHKKDEEKVDEVKTVDTDSLEDDDDIYVSHGHHVLHAHEVMKMEAEIEAVEP 307

  Fly   230 LKRQEIDRPSIGHGSRNKRIFRQF------WNTVAEFDKDRFHRGTFLVKLYLIVKQPIDMLLRI 288
            ||....           :.:...|      |.::.|:|:....:     |:..::....:.|.::
 Worm   308 LKTWSF-----------RGVVHDFKEHLKPWPSMDEWDEMNIFQ-----KVIAVLNTIPNFLFKL 356

  Fly   289 LIPKVDMEAPQYGWSKLLFNIQVVLVPTYIAYIIVRGYSIA------GLAVYMIALILMIPVATL 347
            .||  ..|.|   |||.:..:|.::.|.::.:.| :..||:      ||.:|.:.|.::: .|.:
 Worm   357 TIP--HSEQP---WSKPITLLQCLICPVFLLFCI-QVCSISPFPNSPGLWMYGLILSVLL-TAAV 414

  Fly   348 IFFLTRTDTPPIFFRFTSGVGFMAAVFLIFCLTTEVNAMFFTMATILQVSQEFSLATAICWALSS 412
            :||......||.:....|..||:.::..|:.:::||..:...:..:.:||.|....|.:.|:.|.
 Worm   415 LFFTELHKEPPFYKSLISYAGFLMSIAWIYLISSEVVNVVTMLGVVSRVSHEVLGLTILAWSNSI 479

  Fly   413 NDLVANLSLAHQGWPRMAMTATFSAPVFASFVFLALPLV--------VNSFVNAPGNIFPTEGGF 469
            .||:|::|:|.||:|||||.|.....:|...:...||..        ::..:|      ||.
 Worm   480 GDLIADVSVAKQGYPRMAMAAAIGGQLFNLLIGFGLPFTIAKIQGKSISMIIN------PTY--- 535

  Fly   470 GETVCIFLEVGMGFSMLSVLTTNFKLRRACGFLLVSYYI-FFVGVLILLE 518
             ..:.:||.:.:.|:::::....:.|||...:.||..|| |||.:.:.|:
 Worm   536 -RLLMLFLAISLIFTLIAMFAQKYFLRRIHSYSLVFIYISFFVFIGLSLD 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13223	NP_610656.1	Na_Ca_ex	45..194	CDD:279963	44/161 (27%)
		Na_Ca_ex	365..516	CDD:279963	44/159 (28%)
ncx-6	NP_499146.2	Na_Ca_ex	105..249	CDD:279963	43/153 (28%)
		Na_Ca_ex	431..579	CDD:279963	44/157 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165714
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4675
OMA	1	1.010	-	-		QHG57812
OrthoDB	1	1.010	-	-		D257493at33208
OrthoFinder	1	1.000	-	-		FOG0000933
OrthoInspector	1	1.000	-	-		mtm4752
orthoMCL	1	0.900	-	-		OOG6_101277
Panther	1	1.100	-	-	O	PTHR12266
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1775
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.700