Protein Alignment CG13223 and ncx-7

DIOPT Version :9

• Sequence 1: NP_610656.1
• Gene: CG13223 / 36190
• FlyBaseID: FBgn0033599
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_499147.3
• Gene: ncx-7 / 176370
• WormBaseID: WBGene00003572
• Length: 672
• Species: Caenorhabditis elegans
• Alignment Length: 660
• Identity: 149/660 - (22%)
• Similarity: 257/660 - (38%)
• Gaps: 186/660 - (28%)

  Fly     7 ESQKCKFVQTTPDCLINMNLF---NYLGW-HYCKVDVRNSFNSFWSVLGMFLITIY---VFWMMQ 64
            :.|.|.:|    :|  |.|..   .||.| .|    |..:.::|..|:.:.:..||   :|.|:.
 Worm    52 QEQVCDYV----NC--NDNACEGGGYLLWTQY----VECASSTFSRVILIIVGVIYMLVLFIMVS 106

  Fly    65 ITIKNYFCPTLMVIADLLRMNESTAGVTVLAIANGSPDFFTAIASRVQ--TSKHSFL--SCMSQA 125
            ....::|.|::..|...||::||.||||.:|..||:||.|.:|||.:.  |.|....  ......
 Worm   107 SAADDFFSPSISSIVAHLRISESVAGVTFMAFGNGAPDVFGSIASVLSSPTPKADLALGELFGGG 171

  Fly   126 MFLHIFVAGLVILTKPFNMRANTYLRD------------FGFLFLNTV-----------YMDY-- 165
            :|:...|...:|||.||::...:.:||            |.|:|.|.|           |:.|
 Worm   172 LFVTTMVVSTIILTSPFDVEVFSTIRDLLFYLVALSFLAFCFVFYNRVTLWMPLTFLGLYLLYVI 236

  Fly   166 -------IHKRP-------------KGISWLAALPSAFIFVGYVVVAIVDQH----------LLI 200
                   :|.|.             |.|..|.:..|........|:..::.|          ::.
 Worm   237 TVIGAQAVHNRKRKALQKQNSTKSRKSIKSLRSRKSIHSVAPMPVIPEIEVHDQEAPFPEISVVT 301

  Fly   201 ARIQKMEQRQLNVAEALQ---------------LEELKP---QKEMPLKRQEIDRPS------IG 241
            ..|.|:::.....|:..:               |..|.|   ...:.:.|:|.:...      :.
 Worm   302 GAIDKLKEHMAEKAQTTRRYTKRASFMVNGDGNLNGLHPYATHNHLGISRRESELSDEDEEFVVI 366

  Fly   242 HGS------------------------RNKRIFRQF------------WNTVAEFDKDRFHRGTF 270
            ||.                        |:|.|.:..            |..:..|.|
 Worm   367 HGHVFQGHEARSRAASLVPEPMQIKSWRSKDILKDLAEHLDPRPEAEDWEEMNIFSK-------- 423

  Fly   271 LVKLYLIVKQPIDMLLRILIPKVDMEAPQYGWSK-------------LLFNIQVVLVPTYIAYII 322
             |..|:.|..  ::|.::.||..:|     .|||             |||:||..|...:
 Worm   424 -VMAYINVVP--NLLFKLTIPLNEM-----SWSKPLTLLHAFTCPAFLLFSIQFFLETPF----- 475

  Fly   323 VRGYSIAGLAVYMIALILMIPVATLIFFLTRTDTPPIFFR-FTSGVGFMAAVFLIFCLTTEVNAM 386
               ....||.||.:|:.:::.:..::|  |.....|.::: ..|..||:.::..|:.:::||..:
 Worm   476 ---SGSPGLWVYGLAVSIVLAILIMVF--TELSVQPKYYKEIYSYSGFIMSIAWIYLISSEVVNV 535

  Fly   387 FFTMATILQVSQEFSLATAICWALSSNDLVANLSLAHQGWPRMAMTATFSAPVFASFVFLALPLV 451
            ...:..:.:||.|....|.:.|:.|..||:|::|:..||:|||||.|....|:|...:...||..
 Worm   536 VTMLGVVSRVSHEVLGLTILAWSNSIGDLIADVSVVKQGYPRMAMAAAIGGPLFNLLMGFGLPFT 600

  Fly   452 V----NSFVNAPGNIFPTEGGFGETVCIFLEVGMGFSMLSVLTTNFKLRRACGFLLVSYYIFFVG 512
            :    ..:::.  .|.||.    ..:.:||.:.:..:::.:....|:|:|....:|:|.||.|:.
 Worm   601 IAKLQGKYISM--TINPTY----RLLILFLAISLLATLIGIPVQKFRLQRPHAAVLISIYIAFIV 659

  Fly   513 VLILLEKGVI 522
            .:||.|.||:
 Worm   660 FVILSETGVL 669

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13223	NP_610656.1	Na_Ca_ex	45..194	CDD:279963	51/200 (26%)
		Na_Ca_ex	365..516	CDD:279963	41/154 (27%)
ncx-7	NP_499147.3	PLN03151	56..671	CDD:215604	148/656 (23%)
		Na_Ca_ex	96..240	CDD:279963	42/143 (29%)
		Na_Ca_ex	513..663	CDD:279963	41/155 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165715
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	153	1.000	Inparanoid score	I2937
Isobase	1	0.950	-	0	Normalized mean entropy	S4675
OMA	1	1.010	-	-		QHG57812
OrthoDB	1	1.010	-	-		D257493at33208
OrthoFinder	1	1.000	-	-		FOG0000933
OrthoInspector	1	1.000	-	-		mtm4752
orthoMCL	1	0.900	-	-		OOG6_101277
Panther	1	1.100	-	-	O	PTHR12266
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1775
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.750