Protein Alignment CG13223 and Slc8b1

DIOPT Version :10

• Sequence 1: NP_610656.1
• Gene: CG13223 / 36190
• FlyBaseID: FBgn0033599
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_573484.2
• Gene: Slc8b1 / 170756
• MGIID: 2180781
• Length: 585
• Species: Mus musculus
• Alignment Length: 543
• Identity: 145/543 - (26%)
• Similarity: 247/543 - (45%)
• Gaps: 50/543 - (9%)

  Fly     8 SQKCKFVQTTPDCLINMNLFNYLGWHYCKVDVRNSFNSFWSVLGMFLITIYVFWMMQ------IT 66
            |.:|.||:..|||.......:||...:|         .|...|....||:||||::.      :|
Mouse    62 SDRCDFVRRNPDCRSEAGYLDYLEGIFC---------YFPPNLLPLAITLYVFWLLYLFLILGVT 117

  Fly    67 IKNYFCPTLMVIADLLRMNESTAGVTVLAIANGSPDFFTAIA--SRVQTSKHSFLSCMSQAMFLH 129
            ...:|||.|..|:..|:::.:.||||.||..||:||.|:|:.  |..:|:..:..:.....:.:.
Mouse   118 AAKFFCPNLSAISTNLKLSHNVAGVTFLAFGNGAPDIFSALVAFSDPRTAGLAIGALFGAGVLVT 182

  Fly   130 IFVAGLVILTKPFNMRANTYLRDFG------FLFLNTVYMDYIHKRPKGISWLAALPSAFIFVGY 188
            ..|||.:.:..||...:..:|||..      ||....:|:..|     .::|  ||....::|.|
Mouse   183 TVVAGGITILHPFMAASRPFLRDIAFYMVAVFLTFTALYLGRI-----TLTW--ALGYLGLYVFY 240

  Fly   189 VVVAIVDQHLLIARIQKMEQRQL--NVAEALQLEELKPQKEMPLKRQEID-----RPSIGHGSRN 246
            ||..|:...:    .|:...|.|  :::|..:|.....:.:|.......|     ||.:......
Mouse   241 VVTVIICTWV----YQRQRSRSLVHSISETPELLSESEEDQMSSNTNSYDYGDEYRPLLLGRETT 301

  Fly   247 KRIFRQFWNTVAEFDKDRFHRGTFLVKLYLIVKQPIDMLLRILIPKVDMEAPQYGWSKLLFNIQV 311
            .:|..|..|.:   |..::...:...::..:||.|::.||.:.:|.||.:.....|.:.|..:|:
Mouse   302 VQILIQALNPL---DYRKWRTQSISWRVLKVVKLPVEFLLLLTVPVVDPDKDDRNWKRPLNCLQL 363

  Fly   312 VLVPTYIAYIIVRG----YSIAG-LAVYMIALILMIPVATLIFFLTRTDTPPIFFRFTSGVGFMA 371
            |:.|..:...:..|    |.|.| |.|:.:.:|:...:|::.||.|....||......:.:||:.
Mouse   364 VISPLVLVLTLQSGVYGIYEIGGLLPVWAVVVIVGTALASVTFFATSNREPPRLHWLFAFLGFLT 428

  Fly   372 AVFLIFCLTTEVNAMFFTMATILQVSQEFSLATAICWALSSNDLVANLSLAHQGWPRMAMTATFS 436
            :...|....|||..:..::..|.::|......|.:.|..|..|..::.:||.||:||||.:|.|.
Mouse   429 SALWINAAATEVVNILRSLGVIFRLSNTVLGLTLLAWGNSIGDAFSDFTLARQGYPRMAFSACFG 493

  Fly   437 APVFASFVFLALPLVVNSFVNAPGNI-FPTEGGFGETVCIFLEVGMGFSMLSVLTTNFKLRRACG 500
            ..:|...|.:.|..::....|....: ...:|.....:...|.:.:.||::||....|:|.:|.|
Mouse   494 GIIFNILVGVGLGCLLQIIRNHVVEVKLEPDGLLVWVLASALGLSLIFSLVSVPLQCFQLSKAYG 558

  Fly   501 FLLVSYYIFFVGVLILLEKGVIH 523
            ..|:.:||.|:.|::|.|.||||
Mouse   559 LCLLLFYICFLVVVLLTEFGVIH 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13223	NP_610656.1	PLN03151	10..522	CDD:215604	141/538 (26%)
Slc8b1	NP_573484.2	PLN03151	63..580	CDD:215604	141/539 (26%)