Protein Alignment CG13223 and slc24a4b

DIOPT Version :9

• Sequence 1: NP_610656.1
• Gene: CG13223 / 36190
• FlyBaseID: FBgn0033599
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: XP_002665845.2
• Gene: slc24a4b / 100334346
• ZFINID: ZDB-GENE-081031-75
• Length: 636
• Species: Danio rerio
• Alignment Length: 567
• Identity: 107/567 - (18%)
• Similarity: 192/567 - (33%)
• Gaps: 187/567 - (32%)

  Fly    48 SVLGMFLITIYVFWMMQITIKNYFCPTLMVIADLLRMNESTAGVTVLAIANGSPDFFTAIASRVQ 112
            :||...:..:|:|..:.|...:||..:|..|.:.|.::|..||.|.:|..:.:|:.|.::.....
Zfish   152 AVLLHIIAALYMFLALAIVCDDYFVTSLEKICEKLNLSEDVAGATFMAAGSSAPELFASVIGVFI 216

  Fly   113 TSKHSFL---SCMSQAMF--------LHIFVAGLVILTKPFNMRANTYLRDFGFLFLNTVYMDYI 166
            |  |..:   :.:..|:|        ..||...:|:||      .....||..|..|:.|.: .:
Zfish   217 T--HGDVGVGTIVGSAVFNILCIIGVCGIFAGQVVLLT------WWAVFRDSFFYILSVVAL-IV 272

  Fly   167 HKRPKGISWLAALPSAFIFVGYVVVAIVDQHLLIARIQKMEQRQ-------LNVAEALQLEELK- 223
            ....:.|.|..:|....::..|:::...:     :|:||...|:       .|.|...:||::|
Zfish   273 FIYDEKIVWWESLVLVVMYACYILIMKFN-----SRLQKFFTRKGNKNVANGNAAAGSELEDVKT 332

  Fly   224 --------------------PQKEMP--------------------------LKRQEI------- 235
                                |....|                          .:||.:
Zfish   333 SKIYSRGSVVMVDEIINASPPNYRFPEAGLRVMVTNHFGPKTRLRMASRLIITERQRLVQSANGV 397

  Fly   236 ------DRPSIGHGSRNKRIFRQFWNTVAEFDKDRFHRGTFLV-----------KLYLIVKQPID 283
                  .:|.|.:|:            |.| ||....:.:.|.           :...::..|:.
Zfish   398 ETAVVDGKPDIENGN------------VPE-DKSTEEKESELTTPFRLPDGCMNRTKWLISWPLL 449

  Fly   284 MLLRILIPKVDMEAPQYGWSKLLFNIQVVLVPTYIAYIIVRGYSIAGLAVYMIALI---LMIPVA 345
            ::|...||    ...:..|.| .|.:..:|...:||   |..|    ..|:|:.:|   |.||..
Zfish   450 LILFFTIP----NCAKSRWEK-YFMLSFILSTVWIA---VFSY----FMVWMVTIIGYTLGIPDV 502

  Fly   346 TLIFFLTRTDTPPIFFRFTSGVGFMAAVFLIFCLTTEVNAMFFTMATILQVSQEFSLATAICWAL 410
            .:                  |:.|:||                                    ..
Zfish   503 IM------------------GITFLAA------------------------------------GT 513

  Fly   411 SSNDLVANLSLAHQGWPRMAMTATFSAPVFASFVFLALPLVVNSF-VNAPGNIFPTEGGFGETVC 474
            |..|.:|:|.:|.||...||::.|..:.||...|.|.:|..:.:. ||....:.....|...:|.
Zfish   514 SVPDCIASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPWALQTMAVNYGSVVMINSRGLLYSVV 578

  Fly   475 IFLEVGMGFSMLSVLTTNFKLRRACGFLLVSYYIFFVGVLILLEKGV 521
            :.|. .:..::|.:...::||....|..::..|..|:...|::|..|
Zfish   579 LLLG-SVALTILGIHLNHWKLDFKLGVYVLLLYAVFLCFSIMIEYNV 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13223	NP_610656.1	Na_Ca_ex	45..194	CDD:279963	35/156 (22%)
		Na_Ca_ex	365..516	CDD:279963	30/151 (20%)
slc24a4b	XP_002665845.2	TIGR00367	155..581	CDD:273039	95/518 (18%)
		Na_Ca_ex	156..298	CDD:279963	33/150 (22%)
		Na_Ca_ex	467..619	CDD:279963	42/213 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1775
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840