DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment metro and MAPKKK7

DIOPT Version :9

Sequence 1:	NP_610642.2	Gene:	metro / 36176	FlyBaseID:	FBgn0050021	Length:	595	Species:	Drosophila melanogaster
Sequence 2:	NP_187962.1	Gene:	MAPKKK7 / 820555	AraportID:	AT3G13530	Length:	1368	Species:	Arabidopsis thaliana

Alignment Length:	287	Identity:	66/287 - (22%)
Similarity:	99/287 - (34%)	Gaps:	94/287 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 PALSKLI---STLKESEN-LSNDQEIDFLKAL---LESKELNALVNVHTKV-------AKVG--R 62
            |.|.|::   :.|....| |.|.|..|.:|.|   ||.|:.:.:..:|.:|       .|:.  |
plant  1087 PILLKILECTNHLSTDPNCLENLQRADAIKHLIPNLELKDGHLVYQIHHEVLSALFNLCKINKRR 1151

  Fly    63 DDRLA-----------------------PVLSTSAQVLYEVLEQLSQHCHLN------DD----- 93
            .::.|                       |:|...|.......|||..|..|:      ||
plant  1152 QEQAAENGIIPHLMLFIMSDSPLKQYALPLLCDMAHASRNSREQLRAHGGLDVYLSLLDDEYWSV 1216

  Fly    94 --------CKEAFHLLQDS---HLQHLLFAHDAIAQK--DFYPHLPEAPVEMDEDEETIKIVQLV 145
                    |     |.||:   .::..|...||| ||  ||:...||... :...|..:||:  .
plant  1217 IALDSIAVC-----LAQDNDNRKVEQALLKQDAI-QKLVDFFQSCPERHF-VHILEPFLKII--T 1272

  Fly   146 KSNEPLTGAQSTEPIVGATIKTDEESGKIIIARIMHGGAADRSGLIHVGDEVIE----VNNINVE 206
            ||..    ...|..:.|.|        .::|:|:.|..|..|..|:.:...|.|    ...:.||
plant  1273 KSYR----INKTLAVNGLT--------PLLISRLDHQDAIARLNLLKLIKAVYEHHPRPKQLIVE 1325

  Fly   207 GKTPGDVLTIL------QNSEGTITFK 227
            ...|..:..::      |.|.|.:..|
plant  1326 NDLPQKLQNLIEERRDGQRSGGQVLVK 1352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
metro	NP_610642.2	L27	17..68	CDD:197794	17/89 (19%)
		L27	75..127	CDD:197794	19/75 (25%)
		PDZ_signaling	139..229	CDD:238492	22/99 (22%)
		SH3_MPP	243..302	CDD:212796
		Guanylate_kin	390..575	CDD:279019
		GuKc	399..580	CDD:214504
MAPKKK7	NP_187962.1	STKc_Cdc7_like	19..274	CDD:270797
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000