Protein Alignment metro and mpp3b

DIOPT Version :10

• Sequence 1: NP_610642.2
• Gene: metro / 36176
• FlyBaseID: FBgn0050021
• Length: 595
• Species: Drosophila melanogaster
• Sequence 2: XP_068080842.1
• Gene: mpp3b / 799884
• ZFINID: ZDB-GENE-121214-128
• Length: 611
• Species: Danio rerio
• Alignment Length: 640
• Identity: 229/640 - (35%)
• Similarity: 353/640 - (55%)
• Gaps: 103/640 - (16%)

  Fly    16 LSKLISTLKESENLSNDQEIDFLKALLESKELNALVNVHTKVAKVGRDDRL---APVLSTSAQVL 77
            |:.|.|.|....|  :.:::.||:.:...:.|:.|:.:|.::    |...|   .|||.:::.:.
Zfish    14 LALLTSQLHPEAN--HKEDLVFLREVFSERSLSYLMKIHERL----RQFHLYSPTPVLHSASCLA 72

  Fly    78 YEVLEQLSQHCHLNDDCKEAFHLLQDSHLQHLLFAHDAIAQKDFYPHLPEAPVEMDE--DEETIK 140
            .:|.|:| |:..|.:|.:|...||...|::.:|..||.:|||:|.|.||..|.::::  :||::|
Zfish    73 EDVAEEL-QNGSLEEDERELLALLSTPHIKAVLTVHDTVAQKNFEPVLPPLPNDLEDELEEESVK 136

  Fly   141 IVQLVKSNEPLTGAQSTEPIVGATIKTDEESGKIIIARIMHGGAADRSGLIHVGDEVIEVNNINV 205
            ||:|||:.|||          ||||:.||.:|.:::||||.|||||||||:|||||:.|||...:
Zfish   137 IVRLVKNKEPL----------GATIRRDEVTGAVVVARIMRGGAADRSGLVHVGDELREVNGNLI 191

  Fly   206 EGKTPGDVLTILQNSEGTITFKLVPA-DNKGAQRESKVRVRAHFDYNPDVDPYIPCKEAGLAFQR 269
            ..|.|.::..||..|:|:||.|::|| ..:...:||||.:||.|||.|..|...||:||||.|..
Zfish   192 IHKRPEEISQILSQSQGSITLKIIPAIKEEDRFKESKVYLRALFDYTPYEDRATPCQEAGLPFLC 256

  Fly   270 GDVLHIVAQDDAYWWQARKEHERSARAGLIPSRALQERRILHDRTQKNGTDLDSKPGSCASLCTT 334
            ||||.:|:|||..||||::..:.:.||||||||..||||:|:  ..|.||.             .
Zfish   257 GDVLQVVSQDDPTWWQAKRVGDSNLRAGLIPSRQFQERRLLY--RMKMGTH-------------Q 306

  Fly   335 PPGSPRLPASSSTSSCRQ------------------PKTKKI-------------------MYDL 362
            .|.|||  |:....:|.:                  ||.|.:                   .:.|
Zfish   307 SPKSPR--ATPCDQTCEKEDCDSESSVSGQHVVVVSPKCKAVAPSCGQAFSWEFYSAGLRRSFRL 369

  Fly   363 TEND-----------DFDREQIATYEEVA----KLYPRPGVFRPIVLIGAPGVGRNELRRRLIAR 412
            :..|           :....:...||||.    :|..:|   |.:||||:.|...|||::::||.
Zfish   370 SRKDHQGSNKESHTPESTENEFLIYEEVTLHQMRLQDKP---RLVVLIGSLGARINELKQKVIAE 431

  Fly   413 DPEKFRSPVPYTTRPMRTGEVAGREYIFVAREKMDADIEAGKFVEHGEYKGHLYGTSAESVKSIV 477
            :|:::...||:||||.::.|..|.||.|::::..||||::.||:|:||||.:.||||.||::|::
Zfish   432 NPQRYGVAVPHTTRPRKSHEKEGVEYHFISKQAFDADIQSNKFIEYGEYKNNQYGTSLESIRSVL 496

  Fly   478 NAGCVCVLSPHYQAIKTLRTAQLKPFLIHVKP--PELDILKATRTEARAKSTFDEANARSFTDEE 540
            ....||::....:|:|.|||::.||::|.|||  ||:      |....:.::.:..:....|:|:
Zfish   497 ARNKVCLVDVQPEALKILRTSEFKPYVIFVKPRIPEI------RRHRSSPTSPERGDNGHITEED 555

  Fly   541 FEDMIKSAERIDFLYGHFFDVELVNGELVNAFEQLVQNVQRLENEPVWAPSMWVQ 595
            ..||..|||:::..|||..|..|:..:..:|..:|...::|||.||.|.|..||:
Zfish   556 LLDMKHSAEQMEQQYGHLVDRVLIKEDSASACVELRLILERLEREPQWVPVSWVR 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
metro	NP_610642.2	L27	17..68	CDD:197794	11/53 (21%)
		L27	75..127	CDD:197794	19/51 (37%)
		PDZ_MPP3-MPP4-MPP7-like	140..230	CDD:467260	46/89 (52%)
		SH3_MPP	243..302	CDD:212796	32/58 (55%)
		Guanylate_kin	390..575	CDD:395500	70/186 (38%)
mpp3b	XP_068080842.1	L27	11..55	CDD:460717	10/46 (22%)
		L27	69..119	CDD:460717	18/50 (36%)
		PDZ_MPP3-MPP4-MPP7-like	136..216	CDD:467260	46/89 (52%)
		SH3	230..291	CDD:473055	34/60 (57%)
		GuKc	424..595	CDD:214504	63/176 (36%)