Protein Alignment metro and LOC556594

DIOPT Version :10

• Sequence 1: NP_610642.2
• Gene: metro / 36176
• FlyBaseID: FBgn0050021
• Length: 595
• Species: Drosophila melanogaster
• Sequence 2: XP_073791303.1
• Gene: LOC556594 / 556594
• -ID: -
• Length: 604
• Species: Danio rerio
• Alignment Length: 665
• Identity: 221/665 - (33%)
• Similarity: 330/665 - (49%)
• Gaps: 141/665 - (21%)

  Fly     6 MASDINWDPA--------------LSKLISTLKESENLS-NDQEIDFLKALLESKELNALVNVHT 55
            |..|:..||.              |:.:|:.::.|.|.. |..|:  |..||.:..|.:|:.|
Zfish     1 MKPDMETDPGSAPLEVGDKGLAQILAHVIAEVRGSINKDINGAEL--LYGLLNAPWLQSLLKV-- 61

  Fly    56 KVAKVGRDDRLAPVLSTSAQVLYEVLEQLSQHCHLNDDCKEAFHLLQDSHLQHLLFAHDAIAQKD 120
                                  ||.|::     ||....:..........||.||.|||.::.:|
Zfish    62 ----------------------YECLQR-----HLRGPARPYVSYSSGLSLQALLSAHDTVSLRD 99

  Fly   121 FYPHLPEAPVEMDEDEETIKIVQLVKSNEPLTGAQSTEPIVGATIKTDEESGKIIIARIMHGGAA 185
            :.|.||..|.::.||||.::||.|||:|:||          ||||:.|:.:|:|.|||::|||.|
Zfish   100 YEPDLPPLPNDLPEDEEAMRIVCLVKNNQPL----------GATIRRDDVTGEIYIARVIHGGLA 154

  Fly   186 DRSGLIHVGDEVIEVNNINVEGKTPGDVLTILQNSEGTITFKLVPADNKGAQRESKVRVRAHFDY 250
            |||||:|.||.::|||...|.|..|..::.||.:|.|||.||:||..::....::.:.|||..||
Zfish   155 DRSGLLHAGDRLVEVNGQPVFGLEPEQIIQILAHSHGTIMFKVVPITDRPVNNQTMLYVRAMVDY 219

  Fly   251 NPDVDPYIPCKEAGLAFQRGDVLHIVAQDDAYWWQARKEHERSARAGLIPSRALQERR------- 308
            :|..||.|||.:||:||::.|:|.||.|.|:.||||.|....||.||||||.:|.:|:
Zfish   220 SPQADPSIPCADAGMAFRKCDILEIVDQSDSLWWQAVKLPSTSACAGLIPSTSLLKRKQKEFWWS 284

  Fly   309 -ILHDRT-QKNGTDLDSKPGSCA-----------------------------------------S 330
             ..|..| .|:.:.:|.:....|                                         .
Zfish   285 QPYHPHTCVKSLSTVDEEDDMIAIDEKCVEADEEAFESEELKDEASEFSTNIEGIYLTGFRRSLR 349

  Fly   331 LCTTPPG---------SPRLPASSSTSSCRQPKTKKIMYDLTENDDFDREQIATYEEVAKLYPRP 386
            ||....|         |.|.|| |..||...|                      ||:|.:....|
Zfish   350 LCRRRRGQAFGTSQFCSLRCPA-SCYSSLSNP----------------------YEDVVRYQHHP 391

  Fly   387 -GVFRPIVLIGAPGVGRNELRRRLIARDPEKFRSPVPYTTRPMRTGEVAGREYIFVAREKMDADI 450
             ...|.|.|||..|||.|||||:||..:|:.::.|||:||||.:..|.|||||.||:||:.|:.:
Zfish   392 EHTHRLIALIGPSGVGVNELRRKLIEINPKVYQGPVPHTTRPPKCHEEAGREYHFVSREQFDSMV 456

  Fly   451 EAGKFVEHGEYKGHLYGTSAESVKSIVNAGCVCVLSPHYQAIKTLRTAQLKPFLIHVKPPELDIL 515
            ...:|:|.||.:|||||.|.::||.::.:|.:||:.....|::::||.:|:.::|.:|||.::.:
Zfish   457 CNHRFIEFGELRGHLYGISVDAVKDVLTSGKICVIDIEPYALESVRTPELRAYVIFIKPPTVEQM 521

  Fly   516 KATRTEARAKSTFDEANARSFTDEEFEDMIKSAERIDFLYGHFFDVELVNGELVNAFEQLVQNVQ 580
            |.||..:...:.:  ..:|.|.||:|.::..:..:::..|..|||..:||..|..|..||:..|:
Zfish   522 KRTRMNSNIITNY--YTSRPFRDEDFLEIEDAGRKMEQHYCQFFDHVIVNDGLQAACVQLLTAVR 584

  Fly   581 RLENEPVWAPSMWVQ 595
            |.::||.|.|:.|::
Zfish   585 RAQDEPQWVPTSWIR 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
metro	NP_610642.2	L27	17..68	CDD:197794	11/51 (22%)
		L27	75..127	CDD:197794	15/51 (29%)
		PDZ_MPP3-MPP4-MPP7-like	140..230	CDD:467260	44/89 (49%)
		SH3_MPP	243..302	CDD:212796	33/58 (57%)
		Guanylate_kin	390..575	CDD:395500	73/184 (40%)
LOC556594	XP_073791303.1	None