Protein Alignment metro and mpp2b

DIOPT Version :10

• Sequence 1: NP_610642.2
• Gene: metro / 36176
• FlyBaseID: FBgn0050021
• Length: 595
• Species: Drosophila melanogaster
• Sequence 2: XP_005156123.1
• Gene: mpp2b / 431770
• ZFINID: ZDB-GENE-040704-70
• Length: 561
• Species: Danio rerio
• Alignment Length: 601
• Identity: 205/601 - (34%)
• Similarity: 313/601 - (52%)
• Gaps: 86/601 - (14%)

  Fly    15 ALSKLISTLKE--SENLSNDQEIDFLKALLESKELNALVNVHTKVAKVGR----DDRLAPVLSTS 73
            |:..|:.||.:  |...:||.::.|||.::||              .|.|    :.:|..|...:
Zfish    25 AMQSLLDTLSDSTSSTTANDLDLIFLKGIMES--------------PVSREHYEEPKLEAVRDNN 75

  Fly    74 AQVLYEVLEQLSQHCHLNDDCKEAFHL---LQDSHLQHLLFAHDAIAQKDFYPHLPEAPVEMDE- 134
            .:::.::|..|:.   |:.|...|..|   |::.|.|.||..||::|.|.:....|.....||.
Zfish    76 VELVQDILRDLNT---LSPDSPAAHELICILKEPHFQSLLETHDSVASKSYETPPPSPCAFMDPA 137

  Fly   135 ------DEETIKIVQLVK-SNEPLTGAQSTEPIVGATIKTDEESGKIIIARIMHGGAADRSGLIH 192
                  ..:.:::|.:.| |.|.|          |.|.:.  |.|:::||||:|||..|:.||:|
Zfish   138 FNNQPVPPDAVRMVGIRKVSGEHL----------GVTFRV--EGGELVIARILHGGMIDQQGLLH 190

  Fly   193 VGDEVIEVNNINVEGKTPGDVLTILQNSEGTITFKLVPADNKGAQRESKVRVRAHFDYNPDVDPY 257
            |||.:.|||...| |..|..:..:|:.|.|::..|::|:..: .....:..|:.||||:|..|..
Zfish   191 VGDIIKEVNGKEV-GSDPKVLQNMLKESSGSVVLKILPSYQE-PHTPRQAFVKCHFDYDPSHDNL 253

  Fly   258 IPCKEAGLAFQRGDVLHIVAQDDAYWWQARKEHERSARAGLIPSRALQERRILHDRTQKNGTDLD 322
            ||||||||.|..||:|.|..|:|..||||.  |.....||||||:.|:|:|       |.....|
Zfish   254 IPCKEAGLKFSSGDILQIFNQEDPNWWQAC--HLEGGSAGLIPSQLLEEKR-------KAFVKRD 309

  Fly   323 SKPGSCASLCTTPPGSPRLPASSSTSSCRQPKTKKIMYDLTENDDFDREQIATYEEVAKLYPRPG 387
            .:..|...||....|.               |.||:||..|:|.:|||.::..|||||::.|
Zfish   310 LELASTGPLCAGIGGK---------------KKKKMMYLTTKNAEFDRHELRIYEEVARVPP--- 356

  Fly   388 VFR--PIVLIGAPGVGRNELRRRLIARDPEKFRSPVPYTTRPMRTGEVAGREYIFVAREKMDADI 450
             ||  .:|||||.||||..|:.:|:..||.::.:..|||:|..:..|..|:.|:|::|.:|:.||
Zfish   357 -FRRKTLVLIGAQGVGRRSLKNKLLVSDPHRYGTTTPYTSRKPKVDEKEGQMYLFMSRSEMETDI 420

  Fly   451 EAGKFVEHGEYKGHLYGTSAESVKSIVNAGCVCVLSPHYQAIKTLRTAQLKPFLIHVKPPELDIL 515
            :.|:|:|||||.|:||||..:|:..:|::|.:|:|..:.||:|.||||:..|:::.::.|..::|
Zfish   421 KCGRFLEHGEYDGNLYGTKIDSIHEVVDSGKICILDVNPQALKVLRTAEFLPYVVFIEAPNFEVL 485

  Fly   516 KATRTEARAKSTFDEAN--ARSFTDEEFEDMIKSAERIDFLYGHFFDVELVNGELVNAFEQLVQN 578
            |.....|      .||.  .:..||.|.:..:..:|||...|.|:||:.:||..|..|:..|.:.
Zfish   486 KDMNRSA------IEAGVVTKQMTDSELKRTVDESERIQRAYSHYFDLSIVNDNLDGAYRSLRRA 544

  Fly   579 VQRLENEPVWAPSMWV 594
            :.||..:..|.|..||
Zfish   545 LDRLNTDQQWVPVSWV 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
metro	NP_610642.2	L27	17..68	CDD:197794	14/56 (25%)
		L27	75..127	CDD:197794	15/54 (28%)
		PDZ_MPP3-MPP4-MPP7-like	140..230	CDD:467260	33/90 (37%)
		SH3_MPP	243..302	CDD:212796	32/58 (55%)
		Guanylate_kin	390..575	CDD:395500	71/188 (38%)
mpp2b	XP_005156123.1	L27	76..127	CDD:460717	15/53 (28%)
		PDZ_MPP6-MPP2-like	149..227	CDD:467268	33/90 (37%)
		SH3_MPP2	239..297	CDD:212970	33/59 (56%)
		Guanylate_kin	358..546	CDD:395500	72/193 (37%)