DRSC/TRiP Functional Genomics Resources

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Protein Alignment metro and dlg1

DIOPT Version :9

Sequence 1:NP_610642.2 Gene:metro / 36176 FlyBaseID:FBgn0050021 Length:595 Species:Drosophila melanogaster
Sequence 2:NP_001162718.1 Gene:dlg1 / 32083 FlyBaseID:FBgn0001624 Length:1030 Species:Drosophila melanogaster


Alignment Length:346 Identity:81/346 - (23%)
Similarity:133/346 - (38%) Gaps:92/346 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    24 KESENLSNDQEIDFLKALLESKELNALVNVHTKVAKVGRDDRLAPVLS-------TSAQVLYEVL 81
            |..||::::..:..||::.:...|           .:|:...|....|       :|.|.|.:..
  Fly   630 KNLENVTHELAVATLKSITDKVTL-----------II
GKTQHLTTSASGGGGGGLSSGQQLSQSQ 683

  Fly    82 EQLSQHCHLNDDCKEAFHLLQDSHLQHLLFAHDAIAQKDFYPHLPEAPVEMDEDEETIKIVQLVK 146
            .||:     ....:...|  |..|..               |.:.....|......:..::..|.
  Fly   684 SQLA-----TSQSQSQVH--QQQHAT---------------PMVNSQSTEPGSRYASTNVLAAVP 726

  Fly   147 SNEPLTGAQSTEPI---------------VGATIKTDEESGKIIIARIMHGGAADRSGLIHVGDE 196
            ...|  .|.|||.|               :|..|...|:...|.::.|:.||.||....:..||:
  Fly   727 PGTP--RAVSTEDITREPRTITIQKGPQGLGFNIVGGEDGQGIYVSFILAGGPADLGSELKRGDQ 789

  Fly   197 VIEVNNINVEGKTPGDVLTILQNSEGTITF----------------------KLVPADNKG---- 235
            ::.|||:|:...|..:....|:.|.|.:|.                      ..:.|...|    
  Fly   790 LLSVNNVNLTHATHEEAAQALKTSGGVVTLLAQYRPEEYNRFEARIQELKQQAALGAGGSGTLLR 854

  Fly   236 -AQRESKVRVRAHFDYNPDVDPYIPCKEAGLAFQRGDVLHIVAQDDAYWWQARK---EHERSARA 296
             .|:.| :.|||.|||:|:.|..:|.:  ||.|:.||:||:....|..|||||:   ::| ..:.
  Fly   855 TTQKRS-LYVRALFDYDPNRDDGLPSR--GLPFKHGDILHVTNASDDEWWQARRVLGDNE-DEQI 915

  Fly   297 GLIPSRALQERRI-LHDRTQK 316
            |::||:...||:: ..||:.|
  Fly   916 GIVPSKRRWERKMRARDRSVK 936

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
metroNP_610642.2 L27 17..68 CDD:197794 8/43 (19%)
L27 75..127 CDD:197794 8/51 (16%)
PDZ_signaling 139..229 CDD:238492 27/126 (21%)
SH3_MPP 243..302 CDD:212796 25/61 (41%)
Guanylate_kin 390..575 CDD:279019
GuKc 399..580 CDD:214504
dlg1NP_001162718.1 L27_1 303..359 CDD:286187
PDZ 454..540 CDD:214570
PDZ_signaling 566..655 CDD:238492 6/35 (17%)
PDZ_signaling 742..820 CDD:238492 20/77 (26%)
SH3_DLG-like 862..922 CDD:212795 26/62 (42%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0194
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.810

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