Protein Alignment metro and mpp7a

DIOPT Version :10

• Sequence 1: NP_610642.2
• Gene: metro / 36176
• FlyBaseID: FBgn0050021
• Length: 595
• Species: Drosophila melanogaster
• Sequence 2: XP_021335692.2
• Gene: mpp7a / 30166
• ZFINID: ZDB-GENE-991209-8
• Length: 621
• Species: Danio rerio
• Alignment Length: 632
• Identity: 236/632 - (37%)
• Similarity: 365/632 - (57%)
• Gaps: 67/632 - (10%)

  Fly    14 PALS----------KLISTLKE--SENLSNDQEIDFLKALLESKELNALVNVHTKVAKVGRDDRL 66
            ||||          :|:|.|..  ..::.:..:..||.|:...:.|::||.:|.|: :...|...
Zfish     2 PALSSRSGSEMGLYELLSVLPSQLQPHVESPDDRSFLHAMFGERSLHSLVKIHEKL-QCYEDCAP 65

  Fly    67 APVLSTSAQVLYEVLEQLSQHCHLNDDCKEAFHLLQDSHLQHLLFAHDAIAQKDFYPHLPEAPVE 131
            .|||.::..:..::.|:| |....:::.:|...||...|::.||..||.:|:|.:.|.||..|.:
Zfish    66 TPVLDSAGSLAADLTEEL-QARSASNEIRELVKLLSKPHVKSLLSVHDTVAKKSYDPELPPLPDD 129

  Fly   132 MDEDEETIKIVQLVKSNEPLTGAQSTEPIVGATIKTDEESGKIIIARIMHGGAADRSGLIHVGDE 196
            :|::|:::||::|||:.|||          |||||.||.:|.|::|||:.|||||||||||||||
Zfish   130 IDDEEDSVKIIRLVKNKEPL----------GATIKKDEHTGAILVARILRGGAADRSGLIHVGDE 184

  Fly   197 VIEVNNINVEGKTPGDVLTILQNSEGTITFKLVPADNKGAQ-RESKVRVRAHFDYNPDVDPYIPC 260
            :.|||.|.|:.|.|.:::.||..|:|.||||:||.....|| :|.|:.::|.|||||..|..|||
Zfish   185 LKEVNGIPVDDKKPEEIIRILSQSQGAITFKVVPGIKDEAQSKEPKMFIKALFDYNPAEDKAIPC 249

  Fly   261 KEAGLAFQRGDVLHIVAQDDAYWWQARKEHERSARAGLIPSRALQERRI---------------- 309
            |||||.|::||:|.:::||||.||||:.|.:.:.|||||||:..||||:
Zfish   250 KEAGLGFKKGDILQVMSQDDATWWQAKLEGDGNLRAGLIPSKHFQERRLAVWRPTPVMTLQRTSS 314

  Fly   310 --LHDRTQKNGTDLDSKPGSCASLCTTPPGSPRLPASSSTSSCRQPKTKKIMYDLTENDDFDREQ 372
              .:|.|.....|::.:....:.|........|   .|...|.|..||.|.||:..:::.:|...
Zfish   315 KRFYDDTVNCVEDIEEENEFASYLSGLHVAGLR---RSFRLSRRDKKTNKSMYECKKSEQYDTAD 376

  Fly   373 IATYEEVAKLYPRPG-VFRPIVLIGAPGVGRNELRRRLIARDPEKFRSPVPYTTRPMRTGEVAGR 436
            :.|||||.....:.| ..|.:||:|..|||.|||:|:|:..|.:.|...:|:|:|..|..|..|.
Zfish   377 VPTYEEVTTYRRKHGDRHRLVVLVGPTGVGLNELKRKLLISDTQHFSVTIPHTSRSKRHQESEGV 441

  Fly   437 EYIFVAREKMDADIEAGK-------------------FVEHGEYKGHLYGTSAESVKSIVNAGCV 482
            ||.|:::...:|||:..|                   |:|||||||:.||||.:||:|:::...|
Zfish   442 EYHFISKNLFEADIQNNKKSGYSCFWRSSLPVLQRNRFIEHGEYKGNYYGTSFDSVRSVLSKNKV 506

  Fly   483 CVLSPHYQAIKTLRTAQLKPFLIHVKPPELDILKATRTEARAKS-TFDEANARSFTDEEFEDMIK 546
            |:|......:|.||||:.||:::.||||.::.|:.||..|:..| ..|:.::::|::|:|.:||.
Zfish   507 CLLDVQPHTLKHLRTAEFKPYVVFVKPPCIERLRETRRNAKVISGKDDKTSSKAFSEEDFLEMIS 571

  Fly   547 SAERIDFLYGHFFDVELVNGELVNAFEQLVQNVQRLENEPVWAPSMW 593
            :::.::..|||.|:..:||.:|..||.:|.|.::::|.|..|.|..|
Zfish   572 ASQMMENQYGHLFEKVIVNDDLTVAFSELNQALKKVETEAHWVPISW 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
metro	NP_610642.2	L27	17..68	CDD:197794	13/62 (21%)
		L27	75..127	CDD:197794	15/51 (29%)
		PDZ_MPP3-MPP4-MPP7-like	140..230	CDD:467260	50/89 (56%)
		SH3_MPP	243..302	CDD:212796	34/58 (59%)
		Guanylate_kin	390..575	CDD:395500	76/204 (37%)
mpp7a	XP_021335692.2	None