Protein Alignment metro and Lrguk

DIOPT Version :9

• Sequence 1: NP_610642.2
• Gene: metro / 36176
• FlyBaseID: FBgn0050021
• Length: 595
• Species: Drosophila melanogaster
• Sequence 2: XP_017448017.1
• Gene: Lrguk / 296968
• RGDID: 1308226
• Length: 1271
• Species: Rattus norvegicus
• Alignment Length: 624
• Identity: 124/624 - (19%)
• Similarity: 226/624 - (36%)
• Gaps: 148/624 - (23%)

  Fly    16 LSKLISTLKESENLSNDQEIDFLKALLESKELNALVNVHTKVAKVGRDDRLAPV---LSTSAQVL 77
            |.:||....|:|....:|:.:   ...|..|.:.:.|:..:...|.|::.:|..   |..|.:..
  Rat    63 LHQLIHRSHEAEVEQEEQQEE---GESEESEESEMQNLEDEYDGVLREENVADALDGLGWSGRGT 124

  Fly    78 YEVLEQLS-QHCHLNDDCKEAFHLLQDSHLQHLLFAHDAIAQKDFYPHLPEAPVEMDEDEETIKI 141
            .:|...|: .||.|.|....:.::    |||.|..:.:.|........:|             .:
  Rat   125 EQVYRNLNLSHCELIDVSILSGYV----HLQKLNLSGNRIEDLSCVSCMP-------------YL 172

  Fly   142 VQLVKSNEPLTGAQSTEPIVGATIKTDEESGKI-----------IIARIMHGGAADR-SGLIHVG 194
            ::|..|...||...:.:|......|.|..|.:|           :...|:.....:. :||
  Rat   173 LELNASQNRLTTFFNFKPPQNLKQKVDFSSNQISEMYDLSAYHTLTQLILDNNEIEEITGL---- 233

  Fly   195 DEVIEVNNINVEGKTPGDVLTILQNSEGTITFKLVPADNKGAQRESKVRVRAHFDYNPDVDPYIP 259
            ::.|.:.::::.|..   :.||  ...||:..|::...|.  |.|:                 |.
  Rat   234 EKCISLTHLSLAGNR---ITTI--KGLGTLPIKVLSVSNN--QIET-----------------IT 274

  Fly   260 CKEAGLAFQRGDVLHIVAQDDAYWWQARKEHERSARAGLIPSRALQERRILHDRTQKNGTDLDSK 324
            ..|...|.|..|:.|               ::.|:..|| .:..|.|...|.|...|..::::.
  Rat   275 GLEELKALQNLDLSH---------------NQISSLHGL-ENHDLLEVINLEDNKIKELSEIEY- 322

  Fly   325 PGSCASLCTTPPGSPRLPASSSTSSCRQP-KTKK-----IMYDLTENDDFDREQIATYEE---VA 380
                         ...||.....:..|.| :||.     :::.|....:.|:::|...|:   |.
  Rat   323 -------------IENLPILRVLNLLRNPIQTKPEYWFFVIFMLLRLTELDQQKIKVEEKVYAVN 374

  Fly   381 KLYPRPGV-------------------------------FRPIVLIGAPGVGRNELRRRLIARDP 414
            |..|.|.|                               :..::|.|....|:.||..||..:..
  Rat   375 KYDPPPEVVAAQDHMTHVVNSMSQPQRIFDSTLPSLDAPYPMLILTGPEACGKRELAHRLCRQFS 439

  Fly   415 EKFRSPVPYTTRPMRTGEVAGREYIFVAREKMDADIEAGKFVEHGEYKGHLYGTSAESVKSIVNA 479
            ..||....:||||...||....:|.||::|..|..:..|||:....|..|.||.:.::|:.|...
  Rat   440 TYFRYGACHTTRPPYFGEGDRVDYHFVSQEVFDEMLSMGKFILTFNYGNHNYGLNRDTVEGIARD 504

  Fly   480 GCVCVLSPHYQAIKTLRTAQLKPFLIHVKPPELDILKATRTEARAKSTFDEANARSFTDEEFEDM 544
            |....:....:.|::|:.:..:|..|.|.|.:.:..:.   ..|.|..|..|        |.|..
  Rat   505 GLASCIHMELEGIRSLKYSYFEPRYILVVPMDKEKYEG---YLRRKGLFSRA--------EIEIA 558

  Fly   545 IKSAE---RIDFLYGHFFDVELVNGELVNAFEQLVQNVQ 580
            :...:   :::..:..:||..:...:|..|:::|.:.::
  Rat   559 VSRVDLYVKVNRKFPGYFDAVINADDLDIAYQKLSELIR 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
metro	NP_610642.2	L27	17..68	CDD:197794	10/50 (20%)
		L27	75..127	CDD:197794	11/52 (21%)
		PDZ_signaling	139..229	CDD:238492	19/101 (19%)
		SH3_MPP	243..302	CDD:212796	9/58 (16%)
		Guanylate_kin	390..575	CDD:279019	46/187 (25%)
		GuKc	399..580	CDD:214504	45/183 (25%)
Lrguk	XP_017448017.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0194
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810