DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment metro and SPBC1198.05

DIOPT Version :9

Sequence 1:	NP_610642.2	Gene:	metro / 36176	FlyBaseID:	FBgn0050021	Length:	595	Species:	Drosophila melanogaster
Sequence 2:	NP_595074.1	Gene:	SPBC1198.05 / 2539674	PomBaseID:	SPBC1198.05	Length:	202	Species:	Schizosaccharomyces pombe

Alignment Length:	192	Identity:	50/192 - (26%)
Similarity:	88/192 - (45%)	Gaps:	21/192 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   390 RPIVLIGAPGVGRNELRRRLIARDPEKFRSPVPYTTRPMRTGEVAGREYIFVAREKMDADIEAGK 454
            :|:|:.|..|||::.|.:||:....:|....|.:|||..|.||..|.:|.||.:|:....:...|
pombe    19 KPVVVFGPSGVGKSTLLKRLLKDHGDKLGFSVSHTTRTPRAGEKDGIDYHFVTKEEFQKLVAEEK 83

  Fly   455 FVEHGEYKGHLYGTSAESVKSIVNAGCVCVLSPHYQAIKTLRTAQLKPFLIHVKPPELDIL---- 515
            |||...:.|::||||..:::.:.......:|....|.:..::.:.:....:.:.||.::.|
pombe    84 FVEWAVFSGNMYGTSIMAIQELEAVNKKAILDIDLQGVLQVKASPIDAQYVFLAPPSIEQLEVRL 148

  Fly   516 --KATRTEARAKSTFDEANARSFTDEEFEDMIKSAERIDFLYGHFFDVELVNGELVNAFEQL 575
              :.|..|:......:.|.|      |.|...|...         ||..:||.::..|::||
pombe   149 RGRGTENESAILQRLERARA------EIEYSEKPGN---------FDALIVNDDVEKAYKQL 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
metro	NP_610642.2	L27	17..68	CDD:197794
		L27	75..127	CDD:197794
		PDZ_signaling	139..229	CDD:238492
		SH3_MPP	243..302	CDD:212796
		Guanylate_kin	390..575	CDD:279019	48/190 (25%)
		GuKc	399..580	CDD:214504	47/183 (26%)
SPBC1198.05	NP_595074.1	Gmk	17..201	CDD:223272	50/192 (26%)
SPBC1198.05	NP_595074.1	guanyl_kin	19..201	CDD:213788	50/192 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0194
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810