Protein Alignment metro and magu-3

DIOPT Version :9

• Sequence 1: NP_610642.2
• Gene: metro / 36176
• FlyBaseID: FBgn0050021
• Length: 595
• Species: Drosophila melanogaster
• Sequence 2: NP_491260.2
• Gene: magu-3 / 183676
• WormBaseID: WBGene00016841
• Length: 479
• Species: Caenorhabditis elegans
• Alignment Length: 616
• Identity: 152/616 - (24%)
• Similarity: 240/616 - (38%)
• Gaps: 181/616 - (29%)

  Fly    16 LSKLISTLKESENLSNDQEIDFLKALLESKELNALVNVHTKVAKVGRDDRLAPVLSTSAQVLYEV 80
            ||:|.|   .:||||.     .|..|||..|     |:..|..|....|......::|:
 Worm     7 LSQLRS---NAENLSR-----CLHVLLEKIE-----NIEKKNGKEQDADSTKSNGTSSS------ 52

  Fly    81 LEQLSQHCHLNDDCKEAFHLLQDSHLQHL----------LFAHDAIAQKDFYPHLPEAPVEMDED 135
                      |.|.||.|..::......:          :.....:..|.|:      .:.:|..
 Worm    53 ----------NKDGKEKFEQVEIEEKTEIDPKTGLKKRTIVTERVLTTKTFH------ALALDGP 101

  Fly   136 EETIKIVQLVKSNEPLTGAQSTE-----PIVGATI--------KTDEESGKIIIARI-MHGGAAD 186
            ..|:         .|:..:..|:     ||..:.|        ||..::|::....: .|||..
 Worm   102 SPTM---------TPILRSSGTKNHNYAPIHQSAILLPQYQSRKTTVDAGQLTQVEVEKHGGQL- 156

  Fly   187 RSGLIHVGDEVIEVNNINVEGKTPGDVLT-----------ILQNSEGTITFKLVPADNKGAQRES 240
                  |..::.|.:|.:::   ||||:|           .::|.:|.:...:.||....|....
 Worm   157 ------VVTKINEKSNYDLK---PGDVITQVDGKDVYFRADIENLKGKVELTVEPAGIHCAPANF 212

  Fly   241 KVRVRAHFDYNPDVDPYIPCKEAGLAFQRGDVLHIVAQDDAYWWQARKEHERSARAGLIPSRALQ 305
            . ||:..:..:.|||.  ||....|....|||:.|:::|:. |.|.||
 Worm   213 H-RVQDTYSSHIDVDR--PCLWLDLEVNPGDVIQILSKDEK-WMQVRK----------------- 256

  Fly   306 ERRILHDRTQKNGTDLDSKPGSCASLCTTPPGSPRLPASSSTSSCRQPKTKKIMYDLTENDDFDR 370
                |.|.||..                      .||.|
 Worm   257 ----LGDLTQVG----------------------YLPTS-------------------------- 269

  Fly   371 EQIATYEEVAKLYPRPGVF--RPIVLIGAPGVGRNELRRRLIARDPEKFRSPVPYTTRPMRTGEV 433
               .|.|:|:.|.|    |  |.:||:||.|.||.:::..|:...|..|.:.||.|:|..|.|||
 Worm   270 ---LTMEKVSMLCP----FGRRTLVLLGAVGTGRRDIKSMLLRLAPHYFSTIVPLTSRAQRPGEV 327

  Fly   434 AGREYIFVAREKMDADIEAGKFVEHGEYKGHLYGTSAESVKSIVNAGCVCVLSPHYQAIKTLRTA 498
            .||||.||.:|::...|..|..||.||....||||||:||::.:.:|.:|||....|::..|..|
 Worm   328 EGREYQFVRKEEIYQKIREGGMVEWGELDSQLYGTSADSVRNEIRSGRMCVLDAAPQSVNYLYNA 392

  Fly   499 QLKPFLIHVKPPELDILKATRTEARAKSTFDEANARSFTDEEFEDMIKSAERIDFLYGHFFDVEL 563
            :..||::||.||.::  :.|:.||..::...:...:|..||..:..::...:|        .:.|
 Worm   393 EFMPFVVHVVPPPIE--EFTQLEAVRRTHRTQGQLQSICDESAKIGLECKSKI--------HLTL 447

  Fly   564 VNGELVNAFEQLVQNVQRLENEPVWAPSMWV 594
            ||..:...|::||.:::.|..|..|.|..|:
 Worm   448 VNRNIDVTFKRLVDSLETLRYETQWVPHSWM 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
metro	NP_610642.2	L27	17..68	CDD:197794	16/50 (32%)
		L27	75..127	CDD:197794	7/61 (11%)
		PDZ_signaling	139..229	CDD:238492	21/114 (18%)
		SH3_MPP	243..302	CDD:212796	17/58 (29%)
		Guanylate_kin	390..575	CDD:279019	64/184 (35%)
		GuKc	399..580	CDD:214504	61/180 (34%)
magu-3	NP_491260.2	PDZ	147..204	CDD:381812	14/66 (21%)
		SH3	218..268	CDD:388381	20/95 (21%)
		Guanylate_kin	282..464	CDD:366206	66/191 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0194
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000824
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810