Protein Alignment metro and metro

DIOPT Version :10

• Sequence 1: NP_610642.2
• Gene: metro / 36176
• FlyBaseID: FBgn0050021
• Length: 595
• Species: Drosophila melanogaster
• Sequence 2: XP_061514847.1
• Gene: metro / 1279654
• VectorBaseID: AGAMI1_001949
• Length: 590
• Species: Anopheles gambiae
• Alignment Length: 598
• Identity: 447/598 - (74%)
• Similarity: 518/598 - (86%)
• Gaps: 11/598 - (1%)

  Fly     1 MLEAVMASDINWDPALSKLISTLKESENLSNDQEIDFLKALLESKELNALVNVHTKVAKVGRDDR 65
            |...|||||.::||.:||||::|||:|:||:::::.||:.||:|||||||||||:||||:.:|||
Mosquito     1 MTAVVMASDGSYDPVISKLITSLKEAESLSDEKDLGFLQNLLQSKELNALVNVHSKVAKINKDDR 65

  Fly    66 LAPVLSTSAQVLYEVLEQLSQHCHLNDDCKEAFHLLQDSHLQHLLFAHDAIAQKDFYPHLPEAPV 130
            :||:||.|.|:|.||||.|:..||::..|||.|||||..|||.:|||||||||||||||||:.||
Mosquito    66 IAPLLSASVQILMEVLELLAPRCHISPLCKEVFHLLQTPHLQSILFAHDAIAQKDFYPHLPDIPV 130

  Fly   131 EMDEDEETIKIVQLVKSNEPL-TGAQSTEPIVGATIKTDEESGKIIIARIMHGGAADRSGLIHVG 194
            |:||||||||||||||||||| .||||.|||||||||||||:|||||||||||||||||||||||
Mosquito   131 EVDEDEETIKIVQLVKSNEPLCAGAQSAEPIVGATIKTDEETGKIIIARIMHGGAADRSGLIHVG 195

  Fly   195 DEVIEVNNINVEGKTPGDVLTILQNSEGTITFKLVPADNKGAQRESKVRVRAHFDYNPDVDPYIP 259
            ||||||||||||||||.|||:|||||||||||||||:|.|..||||||||:|:|||.|:.|||||
Mosquito   196 DEVIEVNNINVEGKTPSDVLSILQNSEGTITFKLVPSDGKLDQRESKVRVKAYFDYEPENDPYIP 260

  Fly   260 CKEAGLAFQRGDVLHIVAQDDAYWWQARKEHERSARAGLIPSRALQERRILHDRTQK--NGTDLD 322
            ||||||.|||||:||||:|||:||||||||.|::.|||||||||||||||||:||||  ||   |
Mosquito   261 CKEAGLGFQRGDILHIVSQDDSYWWQARKEGEKTTRAGLIPSRALQERRILHERTQKEPNG---D 322

  Fly   323 SKPGSCASLCTTPPGSPRLPASSSTSSCRQPKTKKIMYDLTENDDFDREQIATYEEVAKLYPRPG 387
            :|.|||||:|:||||||     :....|..|||||||||..||||||||.|||||||||||||||
Mosquito   323 AKKGSCASICSTPPGSP-----NPNHPCGGPKTKKIMYDTAENDDFDREMIATYEEVAKLYPRPG 382

  Fly   388 VFRPIVLIGAPGVGRNELRRRLIARDPEKFRSPVPYTTRPMRTGEVAGREYIFVAREKMDADIEA 452
            ||||||||||||||||||:|||:||||||::|||||||||||.||||||||:||.||||:|||.|
Mosquito   383 VFRPIVLIGAPGVGRNELKRRLVARDPEKYKSPVPYTTRPMRPGEVAGREYLFVTREKMEADIAA 447

  Fly   453 GKFVEHGEYKGHLYGTSAESVKSIVNAGCVCVLSPHYQAIKTLRTAQLKPFLIHVKPPELDILKA 517
            .||:||||||||||||:|:||||||||.|||||.|||||:|:||||||||:::|::||..:.||.
Mosquito   448 SKFIEHGEYKGHLYGTAADSVKSIVNASCVCVLGPHYQALKSLRTAQLKPYIVHIRPPAFEELKK 512

  Fly   518 TRTEARAKSTFDEANARSFTDEEFEDMIKSAERIDFLYGHFFDVELVNGELVNAFEQLVQNVQRL 582
            :||:|||:|||||.|:|.||||||.:||||.|||:|.||||.|.|:||.:|..|||:||....:.
Mosquito   513 SRTKARARSTFDENNSRGFTDEEFMEMIKSDERINFHYGHFCDEEIVNDDLSEAFEKLVNFANKC 577

  Fly   583 ENEPVWAPSMWVQ 595
            |.||:|||:.|||
Mosquito   578 ETEPLWAPASWVQ 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
metro	NP_610642.2	L27	17..68	CDD:197794	32/50 (64%)
		L27	75..127	CDD:197794	36/51 (71%)
		PDZ_MPP3-MPP4-MPP7-like	140..230	CDD:467260	84/90 (93%)
		SH3_MPP	243..302	CDD:212796	45/58 (78%)
		Guanylate_kin	390..575	CDD:395500	139/184 (76%)
metro	XP_061514847.1	None