Protein Alignment metro and sdt

DIOPT Version :10

• Sequence 1: NP_610642.2
• Gene: metro / 36176
• FlyBaseID: FBgn0050021
• Length: 595
• Species: Drosophila melanogaster
• Sequence 2: XP_061507016.1
• Gene: sdt / 1273257
• VectorBaseID: AGAMI1_003603
• Length: 1501
• Species: Anopheles gambiae
• Alignment Length: 664
• Identity: 226/664 - (34%)
• Similarity: 337/664 - (50%)
• Gaps: 147/664 - (22%)

  Fly    45 KELNALVNVHTKVAKVGRDDR-----LAPVLSTSAQVLYEVLEQL-----SQHC----HLNDDCK 95
            :.|...:|.|...|..||...     |.|.::.:..|...|||:.     :..|    .|..||.
Mosquito   869 QRLQGHLNKHGLAALAGRVTAAQSLLLGPGIARALAVRTAVLERRRPKIPNPICPNAQALAKDCV 933

  Fly    96 EAF------------HLLQDSHLQHLLFAHDAIAQ-KDFYP------------------------ 123
            |:.            .||....::.||.|||.||. .|..|
Mosquito   934 ESLAQSRSQTAIELCDLLSTYEMEGLLLAHDRIASTTDRSPIASYGGSPITVPVPLGTASNNTTS 998

  Fly   124 -----------------------HLPEAP------------------------VEMDEDEETIKI 141
                                   .:|..|                        |..|..::.|||
Mosquito   999 NNTTTSNNSINNNTLTSAVKPATVMPSIPNNASLVNNNNNNIAKREPMSVPLGVLRDGSQDHIKI 1063

  Fly   142 VQLVKSNEPLTGAQSTEPIVGATIKTDEESGKIIIARIMHGGAADRSGLIHVGDEVIEVNNINVE 206
            :|:.||:|||          ||||:.:.|:  ::|.|::.||||::|||:|.|||::|||.|.:.
Mosquito  1064 IQIEKSSEPL----------GATIRNEGEA--VVIGRVVRGGAAEKSGLLHEGDEILEVNGIEMR 1116

  Fly   207 GKTPGDVLTILQNSEGTITFKLVPA------DNKGAQRESKVRVRAHFDYNPDVDPYIPCKEAGL 265
            ||:..||..:|.:..||:||.:|||      ...|.:....:.|||||||:|:.|.||||:|.|:
Mosquito  1117 GKSVNDVCALLGSMTGTLTFLVVPAGVPQILPGLGMRDPPVLHVRAHFDYDPEDDLYIPCRELGI 1181

  Fly   266 AFQRGDVLHIVAQDDAYWWQARKE-HERSARAGLIPSRALQERR------ILHD---RTQKNGTD 320
            :||:|||||::::||..||||.:| .|....||||||::.|.:|      |..:   ||:|   |
Mosquito  1182 SFQKGDVLHVISRDDPNWWQAYREGEEDQTLAGLIPSQSFQHQRESMKLAIAGEVGLRTRK---D 1243

  Fly   321 LDSKPGSCASLCTTPPGSPRLPASSSTSSCRQPKTKKIMYDLTENDDFDREQIATYEEVAKLYPR 385
            ::.|.|..::|.....|..:...:||...  .|     :|.....||.|.|:|.||||||..|||
Mosquito  1244 INGKAGGGSTLLCARKGRKKKKKASSEHG--YP-----LYATATADDPDPEEILTYEEVALYYPR 1301

  Fly   386 PGVFRPIVLIGAPGVGRNELRRRLIARDPEKFRSPVPYTTRPMRTGEVAGREYIFVAREKMDADI 450
            ....|||||||.|.:||:|||:||:| |.|:|.:.:|:|:|..|.|||.|::|.|::|::.::||
Mosquito  1302 ASHKRPIVLIGPPNIGRHELRQRLMA-DSERFAAAIPHTSRAQREGEVPGQDYHFISRQQFESDI 1365

  Fly   451 EAGKFVEHGEYKGHLYGTSAESVKSIVNAGCVCVLSPHYQAIKTLRTAQLKPFLIHVKPPELDIL 515
            .|.||||||||:...||||.|:::::|.:|.:|||:.|.|::|.||::.|||:.:.|.||.|:.|
Mosquito  1366 LARKFVEHGEYEKAYYGTSLEAIRAVVASGKICVLNLHPQSLKLLRSSDLKPYTVLVAPPSLEKL 1430

  Fly   516 KATRTEARAKSTFDEANARSFTDEEFEDMIKSAERIDFLYGHFFDVELVNGELVNAFEQLVQNVQ 580
            :..|..          ....:.:||.:::|.:|..::..:||.||:.::|.:...|:.||:..:.
Mosquito  1431 RQKRIR----------TGEPYKEEELKEIIATARDMEARWGHLFDMIIINNDTERAYHQLLAEIN 1485

  Fly   581 RLENEPVWAPSMWV 594
            .||.||.|.||.|:
Mosquito  1486 SLEREPQWVPSSWL 1499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
metro	NP_610642.2	L27	17..68	CDD:197794	7/27 (26%)
		L27	75..127	CDD:197794	20/120 (17%)
		PDZ_MPP3-MPP4-MPP7-like	140..230	CDD:467260	39/89 (44%)
		SH3_MPP	243..302	CDD:212796	35/59 (59%)
		Guanylate_kin	390..575	CDD:395500	75/184 (41%)
sdt	XP_061507016.1	None