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Protein Alignment metro and Card11

DIOPT Version :9

Sequence 1:	NP_610642.2	Gene:	metro / 36176	FlyBaseID:	FBgn0050021	Length:	595	Species:	Drosophila melanogaster
Sequence 2:	NP_780571.2	Gene:	Card11 / 108723	MGIID:	1916978	Length:	1154	Species:	Mus musculus

Alignment Length:	657	Identity:	127/657 - (19%)
Similarity:	227/657 - (34%)	Gaps:	224/657 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 APVLSTSAQVLYEVLEQLSQHC-----HLNDDCKEAF-------HLLQDSHLQHLLFAHDA---- 115
            ||..||        :|:.:..|     .|:|:..|.:       |....||....|.|:|.
Mouse   581 APHRST--------VEEDNDSCGFDALDLDDENHERYSFGPPSIHSSSSSHQSEGLDAYDLEQVN 637

  Fly   116 IAQKDFYPHLPEAPVEMDEDEETIKIVQLVKSNEPL---TGAQSTEPIVGATIKTDEESGKIIIA 177
            :..:.|....|..|        ::.....|:...||   |.......|...|:......|..|.:
Mouse   638 LMLRKFSLERPFRP--------SVTSGGHVRGTGPLVQHTTLNGDGLITQLTLLGGNARGSFIHS 694

  Fly   178 RIMHGGAADRSGLIHVGDEVI--------EVNNINVEGKTPGDVLTILQNSEGTIT--FKLVPAD 232
             :..|..|:|:|| ..|.:::        |..::.::..|..:....:|...|.||  :|:   :
Mouse   695 -VKPGSLAERAGL-REGHQLLLLEGCIRGERQSVPLDACTKEEARWTIQRCSGLITLHYKV---N 754

  Fly   233 NKGAQRESK------------VRVRAHFDYNPDVDPYIPCKEAGLAFQRGDVLHI---VAQDDAY 282
            ::|.::..|            ..:|.:.:.:..:|      ...::.:..||:|:   :.||...
Mouse   755 HEGYRKLLKEMEDGLITSGDSFYIRLNLNISSQLD------ACSMSLKCDDVVHVLDTMYQDRHE 813

  Fly   283 WWQARKE--HERSARAGLIP--SRALQ-----ERRILHDRTQKNGTDLDSKPGSCASLCTT---- 334
            |..||.:  .::....|.||  |||.|     .:|::|   :.|..:.||...:..||..|
Mouse   814 WLCARVDPFTDQDLDTGTIPSYSRAQQLLLVKLQRLVH---RGNREEADSAHHTLRSLRNTLQPE 875

  Fly   335 -------PPGSPRLPASS-----------------------------------STSSCRQPKTKK 357
                   |..||||..:|                                   |.|......||.
Mouse   876 EMLSTSDPRVSPRLSRASFFFGQLLQFVSRSENKYKRMNSNERVRIISGSPLGSLSRSSLDATKL 940

  Fly   358 IMYDLTE-NDDFDREQ-------IATYEEVAKLY---PRPGVFRPIV--------LIGAPGVGRN 403
                ||| :::.|.|.       :..|..|...:   .||.:|.|.:        |:.:.|....
Mouse   941 ----LTEKHEELDPENELSRNLTLIPYSLVRAFHCERRRPVLFTPTMLAKTLVQKLLNSGGAMEF 1001

  Fly   404 EL-RRRLIARDPEKFRSPVPYTTRPMRTGEVAGREYIFVAREK--------MDADIEAGKFVEHG 459
            .: :..::.||  :|       .|..:|      |.|..:|||        :.|:|||
Mouse  1002 TICKSDIVTRD--EF-------LRKQKT------ETIIYSREKNPNTFECIVPANIEA------- 1044

  Fly   460 EYKGHLYGTSAESVKSIVNAGCVCVLSPHYQAIKTLRTAQLKPFLIHVKPPELDILKATRTEARA 524
                    .:|::...::.||..||        :.|...::.|.::.::..|.:|.:
Mouse  1045 --------VAAKNKHCLLEAGIGCV--------RDLIKCKVYPIVLLIRVSEKNIKR-------- 1085

  Fly   525 KSTFDEANARSFTDEEFEDMI----KSAERIDFLYGHFFDVELVNGELVNAFEQLVQ----NVQR 581
               |.:...|..|:|||..:.    |..|.:..||.      .|..|:.::.|:|::    .:..
Mouse  1086 ---FRKLLPRPETEEEFLRVCRLKEKELEALPCLYA------TVEAEMWSSVEELLRVLKDKIVE 1141

  Fly   582 LENEPVW 588
            .:.:.:|
Mouse  1142 EQRKTIW 1148

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.