Protein Alignment metro and mpp7b

DIOPT Version :10

• Sequence 1: NP_610642.2
• Gene: metro / 36176
• FlyBaseID: FBgn0050021
• Length: 595
• Species: Drosophila melanogaster
• Sequence 2: XP_073778699.1
• Gene: mpp7b / 101882129
• ZFINID: ZDB-GENE-141212-293
• Length: 575
• Species: Danio rerio
• Alignment Length: 587
• Identity: 236/587 - (40%)
• Similarity: 343/587 - (58%)
• Gaps: 39/587 - (6%)

  Fly    16 LSKLISTLKESENLSNDQEIDFLKALLESKELNALVNVHTKVAKVGRDDRLAPVLSTSAQVLYEV 80
            |:.|:..|:...:.|.|.  .||:.:|....|:.|:.|:.::.|. |..|.||:|.::..:.:.:
Zfish    16 LASLLYGLESHMDTSEDS--SFLQDMLMGNTLHLLIKVYDRLQKY-RAQRPAPLLDSTQGLAHRL 77

  Fly    81 LEQLSQHCHLNDDCKEAFHLLQDSHLQHLLFAHDAIAQKDFYPHLPEAPVEMD---EDEETIKIV 142
            .|:|....: :.:..|..:||...|:|.||..||.:|||.|.|.||..|...|   |||::||||
Zfish    78 AEELQDTVN-SPETTELLNLLSKPHVQTLLLVHDVVAQKRFDPRLPPLPPLPDCNEEDEDSIKIV 141

  Fly   143 QLVKSNEPLTGAQSTEPIVGATIKTDEESGKIIIARIMHGGAADRSGLIHVGDEVIEVNNINVEG 207
            .|||:.|||          |||||.||.||.||:||:|.|||||||||||.||.:.|||.:.||.
Zfish   142 CLVKNQEPL----------GATIKRDESSGAIIVARVMRGGAADRSGLIHEGDMLKEVNGVPVED 196

  Fly   208 KTPGDVLTILQNSEGTITFKLVPADNKGAQ-RESKVRVRAHFDYNPDVDPYIPCKEAGLAFQRGD 271
            |...:::.||..|||.:|||:||..|:..: .:::|.|||.|||:|..||.|||::|||.|||||
Zfish   197 KNLQEIIPILAKSEGAVTFKVVPGTNEELETNDTQVFVRALFDYDPQADPAIPCRDAGLEFQRGD 261

  Fly   272 VLHIVAQDDAYWWQARKEHERSARAGLIPSRALQERRILHDRTQKNGTDLDSKPGSCASLCTTPP 336
            ||.||:|||..|||||:..:.:.||||||||.|||||::..|.:.    |...|....:......
Zfish   262 VLQIVSQDDDTWWQARRHGDANLRAGLIPSRQLQERRVMLQRPEV----LFHSPRVSRAFSAGLR 322

  Fly   337 GSPRLPASSSTSSCRQPKTKKIMYDLTENDDFDREQIATYEEVAKLYPR----PGVFRPIVLIGA 397
            .|.||....:||...:.|..::...:         .:..|::|. ||.|    |  :|.::|.|.
Zfish   323 SSFRLSRKKNTSQEVKQKIGEVHSGI---------HVPIYQDVL-LYQRNPEEP--YRLVLLTGP 375

  Fly   398 PGVGRNELRRRLIARDPEKFRSPVPYTTRPMRTGEVAGREYIFVAREKMDADIEAGKFVEHGEYK 462
            .|||..||:|||:..|||.|...||||||..|..|..|.||.||::...:.||...||:|:||:.
Zfish   376 SGVGVTELKRRLLLSDPEHFCVTVPYTTRERRKQEKDGVEYHFVSKHTFEKDILDHKFLEYGEHN 440

  Fly   463 GHLYGTSAESVKSIVNAGCVCVLSPHYQAIKTLRTAQLKPFLIHVKPPELDILKATRTEARA-KS 526
            |:.||||.:||:.::....||:|.....:|..|.|::.||:::.||||.::.|:.:|.:|:. .|
Zfish   441 GNYYGTSLDSVRRVLTESKVCLLDVKPHSITALYTSEFKPYVVFVKPPSIEQLRQSRRKAKVLTS 505

  Fly   527 TFDEANARSFTDEEFEDMIKSAERIDFLYGHFFDVELVNGELVNAFEQLVQNVQRLENEPVWAPS 591
            ..::.:.|.||:|:|::||.||:.::..|||.|:..::|.:|..||.:|...:.:.|.|..|.|:
Zfish   506 QNEQISTRIFTEEDFQNMISSAQSMEHNYGHLFEKVIINEDLAAAFTELRAALAKTETETRWIPN 570

  Fly   592 MW 593
            .|
Zfish   571 AW 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
metro	NP_610642.2	L27	17..68	CDD:197794	13/50 (26%)
		L27	75..127	CDD:197794	17/51 (33%)
		PDZ_MPP3-MPP4-MPP7-like	140..230	CDD:467260	50/89 (56%)
		SH3_MPP	243..302	CDD:212796	38/58 (66%)
		Guanylate_kin	390..575	CDD:395500	75/185 (41%)
mpp7b	XP_073778699.1	None