Protein Alignment metro and card14

DIOPT Version :9

• Sequence 1: NP_610642.2
• Gene: metro / 36176
• FlyBaseID: FBgn0050021
• Length: 595
• Species: Drosophila melanogaster
• Sequence 2: XP_002937355.2
• Gene: card14 / 100486738
• XenbaseID: XB-GENE-989887
• Length: 972
• Species: Xenopus tropicalis
• Alignment Length: 607
• Identity: 113/607 - (18%)
• Similarity: 212/607 - (34%)
• Gaps: 167/607 - (27%)

  Fly    13 DPALSKLISTLKESENLS------NDQEIDFLKALLESKE-----------LNAL----VNVHTK 56
            |...:::.:.|.|.::|.      .|:..:.|:.:|..:|           |:|.    |:..:|
 Frog   362 DMVQTEISTILAEKDSLRQQVMELTDRNSELLQQILSLQEQLQTQREMRGSLHACEQRDVSTKSK 426

  Fly    57 VAKVGRDDRLAPVLSTSAQVLYEVLEQLSQH-CHLNDDCKEAFHLLQDSHLQHLLFAHDAIAQKD 120
            ..::.|...:.|....|..:...:.|..::: |..:.|..|:|:.....|..:|.....: |.:|
 Frog   427 HMRLVRMYAVCPSEEGSRSLSSSISETWTENSCQTSSDLGESFNSYAPPHDDYLTDLTKS-ASQD 490

  Fly   121 FYPHLPEAPVEMD-EDEETIKIVQLVKSNEPLT--------------GAQSTEPIVGATIKTDE- 169
            ....|.....|.| |.||.:.:...::|:|..:              ..:.|..:.....:.|:
 Frog   491 LPDLLQTEKTETDSEYEEGLPMFSQMQSSESCSSYNNLAISVPRRRHACRDTSRVTVIAFQGDDL 555

  Fly   170 ----------ESGKIIIARIMHGGAADRSGLIHVGDEVIEVN--------NINVEGKTPGDVLTI 216
                      .:| |.|.|:..|.|||...| ..|.::|.|:        .:.:||.|..|...|
 Frog   556 LKQISIIGGNRTG-IFIHRVTEGSAADEMSL-RPGYQIIAVDFDVLNPSYKVALEGMTSEDAHCI 618

  Fly   217 LQNSEG--TITFKLVPADNKGAQRESKVRVRAHFDYNPDVDPYIPCKEA-------GLAFQRGDV 272
            |....|  .::.|.    ||...|:....:.:....:.| ..|:...::       ||....|::
 Frog   619 LNRVNGFCCLSVKC----NKDEYRKLLRDIESGSVSSGD-SFYVQVNQSMAGRVGGGLQVTCGEI 678

  Fly   273 LHI--VAQDDAYWWQARKEHE---RSARAGLIPSRALQERRI---LHDRTQKNG----------- 318
            |||  .....:|.|.|.:.:.   :...:|:||:....::::   :...|.:||
 Frog   679 LHITDTMYKGSYQWFAHRVNAYTMKDGESGIIPNYPQAQQQLITTIQHLTWQNGTPRRPQKQIRI 743

  Fly   319 ------------TDLDSKPGSCASLCTTPPGSPRLPASSSTSSCRQPKTKKIMYDLTENDDFDRE 371
                        |.||.  |.|.  |..||....|..|..|         .:.|.|..:
 Frog   744 VSTDRCNSHLLWTSLDC--GICQ--CEDPPAGSVLGTSCFT---------LLPYTLVTH------ 789

  Fly   372 QIATYEEVAKLYPRPGVFRPIVLIGAPGVGRNELRRRLIARD----PEKFRSPVPYTTRPMRTGE 432
                   :..:.|||.:..|.:|      ||....:...::|    ..::.:...|:.|.:| |:
 Frog   790 -------LKTVIPRPVLLVPSLL------GRILSEKLCSSKDFIKCDTEYLTDAEYSARYLR-GD 840

  Fly   433 VAGREYIFVAREKMDADIEAGKFVEHGEYKGHLYGTSAESVKSIVNAGCVCVLSPHYQAIKTLRT 497
            :.|        ||...|:..              ..:.::|:|:......|:|......:..|..
 Frog   841 IIG--------EKEREDVRC--------------CFTRQNVESVAKQNAHCILELGLSCLSALLR 883

  Fly   498 AQLKPFLIHVKPPELDILKATR 519
            ..:.|.::|:...|    |:|:
 Frog   884 VGIYPIILHIPLTE----KSTK 901

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
metro	NP_610642.2	L27	17..68	CDD:197794	12/71 (17%)
		L27	75..127	CDD:197794	10/52 (19%)
		PDZ_signaling	139..229	CDD:238492	24/124 (19%)
		SH3_MPP	243..302	CDD:212796	14/70 (20%)
		Guanylate_kin	390..575	CDD:279019	23/134 (17%)
		GuKc	399..580	CDD:214504	21/125 (17%)
card14	XP_002937355.2	DD	26..104	CDD:387368
		Smc	<146..>413	CDD:224117	8/50 (16%)
		PDZ_signaling	559..631	CDD:238492	19/73 (26%)
		SH3	653..717	CDD:388381	14/64 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910