Protein Alignment metro and mpp4b

DIOPT Version :10

• Sequence 1: NP_610642.2
• Gene: metro / 36176
• FlyBaseID: FBgn0050021
• Length: 595
• Species: Drosophila melanogaster
• Sequence 2: XP_073809773.1
• Gene: mpp4b / 100331226
• ZFINID: ZDB-GENE-091021-2
• Length: 653
• Species: Danio rerio
• Alignment Length: 666
• Identity: 227/666 - (34%)
• Similarity: 348/666 - (52%)
• Gaps: 113/666 - (16%)

  Fly     5 VMASDINWDPA--------------LSKLISTLKESENLS-NDQEIDFLKALLESKELNALVNVH 54
            :|..|:..||.              |:.:|:.::.|.|.. |..|:  |..||.:..|.:|:.|:
Zfish    21 LMKPDMETDPGSAPLEVGDKGLTQILAHVIAEVRGSINKDINGAEL--LYGLLNAPWLQSLLKVY 83

  Fly    55 TKVAKVGRDDRLAPVLSTSAQVLYEVLEQLSQHCHLNDDCKEAFHLLQDSHLQHLLFAHDAIAQK 119
            ..:.:..|.. ..|.:|.|:.:..::|..|....:.:::.:|.:.||...|||.||.|||.::.:
Zfish    84 ECLQRHLRGP-ARPYVSYSSGLSLQILSDLLAVPNPSNEARELYDLLGQPHLQALLSAHDTVSLR 147

  Fly   120 DFYPHLPEAPVEMDEDEETIKIVQLVKSNEPLTGAQSTEPIVGATIKTDEESGKIIIARIMHGGA 184
            |:.|.||..|.::.||||.::||.|||:|:||          ||||:.|:.:|:|.|||::|||.
Zfish   148 DYEPDLPPLPNDLPEDEEAMRIVCLVKNNQPL----------GATIRRDDVTGEIYIARVIHGGL 202

  Fly   185 ADRSGLIHVGDEVIEVNNINVEGKTPGDVLTILQNSEGTITFKLVPADNKGAQRESKVRVRAHFD 249
            ||||||:|.||.::|||...|.|..|..::.||.:|.|||.||:||..::....::.:.|||..|
Zfish   203 ADRSGLLHAGDRLVEVNGQPVFGLEPEQIIQILAHSHGTIMFKVVPITDRPVNNQTMLYVRAMVD 267

  Fly   250 YNPDVDPYIPCKEAGLAFQRGDVLHIVAQDDAYWWQARKEHERSARAGLIPSRALQERR------ 308
            |:|..||.|||.:||:||::||:|.||.|.|:.||||.|....||.||||||.:|.:|:
Zfish   268 YSPQADPSIPCADAGMAFRKGDILEIVDQSDSLWWQAVKLPSTSACAGLIPSTSLLKRKQKEFWW 332

  Fly   309 --ILHDRT-QKNGTDLDSKPGSCA----------------------------------------- 329
              ..|..| .|:.:.:|.:....|
Zfish   333 SQPYHPHTCVKSLSTVDEEDDMIAIDEKCVEADEEAFESEELKDEESEFSTNIEGIYLTGFRRSL 397

  Fly   330 SLCTTPPG---------SPRLPASSSTSSCRQPKTKKIMYDLTENDDFDREQIATYEEVAKLYPR 385
            .||....|         |.|.|| |..||...|                      ||:|.:....
Zfish   398 RLCRRRRGQAFGTSQFCSLRCPA-SCYSSLSNP----------------------YEDVVRYQHH 439

  Fly   386 P-GVFRPIVLIGAPGVGRNELRRRLIARDPEKFRSPVPYTTRPMRTGEVAGREYIFVAREKMDAD 449
            | ...|.|.|||..|||.|||||:||..:|:.::.|||:||||.:..|.|||||.||:||:.|:.
Zfish   440 PEHTHRLIALIGPSGVGVNELRRKLIEINPKVYQGPVPHTTRPPKCHEEAGREYHFVSREQFDSM 504

  Fly   450 IEAGKFVEHGEYKGHLYGTSAESVKSIVNAGCVCVLSPHYQAIKTLRTAQLKPFLIHVKPPELDI 514
            :...:|:|.||.:|||||.|.::||.::.:|.:||:.....|::::||.:|:.::|.:|||.::.
Zfish   505 VCNHRFIEFGELRGHLYGISVDAVKDVLTSGKICVIDIEPYALESVRTPELRAYVIFIKPPTVEQ 569

  Fly   515 LKATRTEARAKSTFDEANARSFTDEEFEDMIKSAERIDFLYGHFFDVELVNGELVNAFEQLVQNV 579
            :|.||..:...:.:  ..:|.|.||:|.::..:..:::..|..|||..:||..|..|..||:..|
Zfish   570 MKRTRMNSNIITNY--YTSRPFRDEDFLEIEDAGRKMEQHYCQFFDHVIVNDGLQAACVQLLTAV 632

  Fly   580 QRLENEPVWAPSMWVQ 595
            :|.::||.|.|:.|::
Zfish   633 RRAQDEPQWVPTSWIR 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
metro	NP_610642.2	L27	17..68	CDD:197794	12/51 (24%)
		L27	75..127	CDD:197794	16/51 (31%)
		PDZ_MPP3-MPP4-MPP7-like	140..230	CDD:467260	44/89 (49%)
		SH3_MPP	243..302	CDD:212796	34/58 (59%)
		Guanylate_kin	390..575	CDD:395500	73/184 (40%)
mpp4b	XP_073809773.1	None