Protein Alignment metro and mpp7

DIOPT Version :9

• Sequence 1: NP_610642.2
• Gene: metro / 36176
• FlyBaseID: FBgn0050021
• Length: 595
• Species: Drosophila melanogaster
• Sequence 2: XP_031759046.1
• Gene: mpp7 / 100127657
• XenbaseID: XB-GENE-950404
• Length: 601
• Species: Xenopus tropicalis
• Alignment Length: 605
• Identity: 241/605 - (39%)
• Similarity: 374/605 - (61%)
• Gaps: 39/605 - (6%)

  Fly    13 DPALSKLISTL--KESENLSNDQEIDFLKALLESKELNALVNVHTKVAKVGRDDRLAPVLSTSAQ 75
            |..|.::::||  :...::.:.:::.||..:...|.|::||.:|.|:....:::.: ||:.::..
 Frog    11 DTGLYEILATLPAQLQPHVDSQEDLTFLWDMFGEKSLHSLVKIHEKLHYYEKENPM-PVIHSATA 74

  Fly    76 VLYEVLEQLSQHCHLNDDCKEAFHLLQDSHLQHLLFAHDAIAQKDFYPHLPEAPVEMDEDEETIK 140
            :..|:.|:| |...||.:.:|...||...:|:.||..||.:|||.:.|.||..|.::|:||:::|
 Frog    75 LAEELAEEL-QSKSLNSEIRELLKLLSKPNLKALLSVHDTVAQKSYDPVLPPMPDDIDDDEDSVK 138

  Fly   141 IVQLVKSNEPLTGAQSTEPIVGATIKTDEESGKIIIARIMHGGAADRSGLIHVGDEVIEVNNINV 205
            |::|||:.|||          |||||.||::|.|::||||.|||||||||||||||:.|||.|:|
 Frog   139 IIRLVKNREPL----------GATIKKDEKTGAIVVARIMRGGAADRSGLIHVGDELREVNGISV 193

  Fly   206 EGKTPGDVLTILQNSEGTITFKLVPA-DNKGAQRESKVRVRAHFDYNPDVDPYIPCKEAGLAFQR 269
            |.|.|.:::.||..|:|.||||::|: ..:....:.|:.|:|.|||.|:.|..||||||||:|::
 Frog   194 EDKKPEEIIHILAQSQGAITFKIIPSIKEEPPNNDGKMFVKALFDYYPNEDKAIPCKEAGLSFRK 258

  Fly   270 GDVLHIVAQDDAYWWQARKEHERSARAGLIPSRALQERR------ILHDRTQK-----------N 317
            ||:|.|::||||.||||:.|.:.:.|||||||:..||||      ::.::.||           .
 Frog   259 GDILQIMSQDDATWWQAKHEGDANPRAGLIPSKQFQERRFALRKPVVSNQPQKVPNRKSYEETVE 323

  Fly   318 GTDLDSKPGSCA-SLCTTPPGSPRLPASSSTSSCRQPKTKKIMYDLTENDDFDREQIATYEEVAK 381
            ..:::......| |..|...|..|    |...|.:..||.|.||:..::|.:|...:.||||||.
 Frog   324 YEEIEEDAEFAAHSTGTYLAGFRR----SFRLSRKDRKTNKFMYECKKSDQYDTADVPTYEEVAL 384

  Fly   382 LYPRPG-VFRPIVLIGAPGVGRNELRRRLIARDPEKFRSPVPYTTRPMRTGEVAGREYIFVAREK 445
            ...:|. .:|.::|:|..|||.|||:|:::..:.:.:...||:|||..|:.|..|.||||:::..
 Frog   385 YQRKPNEKYRLVILVGPVGVGVNELKRKVLIGNSQHYGVTVPHTTRGKRSQENDGVEYIFISKHL 449

  Fly   446 MDADIEAGKFVEHGEYKGHLYGTSAESVKSIVNAGCVCVLSPHYQAIKTLRTAQLKPFLIHVKPP 510
            .:.||...||:|:||||.:.||||.:||:|::....:|:|.....::|.|||::.|||:|.:|||
 Frog   450 FETDIHNNKFIEYGEYKNNYYGTSLDSVRSVLAKNKICLLDVQPNSLKHLRTSEFKPFVIFIKPP 514

  Fly   511 ELDILKATRTEARAKSTFDEAN-ARSFTDEEFEDMIKSAERIDFLYGHFFDVELVNGELVNAFEQ 574
            .::.|:.||..|:..|..||.. |:.|:||:||:||:|||.::..|.||||..:||.:|..|:.:
 Frog   515 TIERLRETRRNAKVISGKDERGAAKPFSDEDFEEMIQSAEAMEAQYDHFFDTTIVNDDLSAAYNE 579

  Fly   575 LVQNVQRLENEPVWAPSMWV 594
            |...::|||.|..|.|..|:
 Frog   580 LRSTLERLEMEGFWVPVSWL 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
metro	NP_610642.2	L27	17..68	CDD:197794	10/52 (19%)
		L27	75..127	CDD:197794	19/51 (37%)
		PDZ_signaling	139..229	CDD:238492	52/89 (58%)
		SH3_MPP	243..302	CDD:212796	35/58 (60%)
		Guanylate_kin	390..575	CDD:279019	78/185 (42%)
		GuKc	399..580	CDD:214504	76/181 (42%)
mpp7	XP_031759046.1	L27	12..68	CDD:197794	11/56 (20%)
		L27	<87..125	CDD:197794	15/37 (41%)
		PDZ_signaling	137..217	CDD:238492	52/89 (58%)
		SH3_MPP7	232..292	CDD:212966	36/59 (61%)
		GuKc	403..585	CDD:214504	76/181 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	92	1.000	Domainoid score	I7515
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1455
Inparanoid	1	1.050	435	1.000	Inparanoid score	I1658
OMA	1	1.010	-	-		QHG49437
OrthoDB	1	1.010	-	-		D245552at33208
OrthoFinder	1	1.000	-	-		FOG0000824
OrthoInspector	1	1.000	-	-		oto103543
Panther	1	1.100	-	-	LDO	PTHR23122
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5259
SonicParanoid	1	1.000	-	-		X2258
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110