DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7737 and PAO5

DIOPT Version :9

Sequence 1:	NP_001286308.1	Gene:	CG7737 / 36174	FlyBaseID:	FBgn0033584	Length:	543	Species:	Drosophila melanogaster
Sequence 2:	NP_194701.1	Gene:	PAO5 / 829093	AraportID:	AT4G29720	Length:	533	Species:	Arabidopsis thaliana

Alignment Length:	565	Identity:	155/565 - (27%)
Similarity:	234/565 - (41%)	Gaps:	120/565 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 KIVVIGAGASGVACATKL-------LELGFQNVLVVEAEDRLGGRIHTIPFADNVIDLGAQWCHG 102
            :||:||||.:|:..|.||       .||.     |||...|:||||:|..|:...|::||.|.||
plant     6 RIVIIGAGMAGLTAANKLYTSSNNTFELS-----VVEGGSRIGGRINTSEFSSEKIEMGATWIHG 65

  Fly   103 ERDNIVYELTRKQDEELLESTGPVY--ENYECVRSNGD--------------VVPEEVSSRLKAI 151
            ...:.||.:.::        ||.:.  |.:||:.|..|              .:.|.:|....|:
plant    66 IGGSPVYRIAKE--------TGSLVSDEPWECMDSTIDKAKTFAEGGFEIEPSIVESISGLFTAL 122

  Fly   152 V----------GDSLVTR-----QLELRHC----SGSLGSYLTNKF---YDTLRRPENSDIDA-- 192
            :          .|:.::|     :...|.|    |.|:||:|.:.|   :|::.......:..
plant   123 MELAQGKEISQSDADLSRLAHIYETATRVCSKGSSTSVGSFLKSGFDAYWDSISNGGEEGVKGYG 187

  Fly   193 --------EVASEFFVNYQKFENSVEASDTLEQVSGRGYLDYWECEGDILLNWKDKGYVELLRLL 249
                    |.....|.|.|:...|.:...||:..:...|..:...|..|.     |||:.::..|
plant   188 KWSRKSLEEAIFTMFSNTQRTYTSADELSTLDFAAESEYQMFPGEEITIA-----KGYLSVIHHL 247

  Fly   250 MRSRELNVEHGVLEQRLL-LGTRVVKINWNRNDGRVELQMSNGETCIADHVVVTVSLGVLK---D 310
            .         .||.|.:: |..:|.||.|..|:  |:|..|:|....||||:|||||||||   :
plant   248 A---------SVLPQGVIQLNRKVTKIEWQSNE--VKLHFSDGSVVFADHVIVTVSLGVLKAGIE 301

  Fly   311 QHLRLFEPQLPVEKQRAIDGLAFGTVNKIFVEFPEAFWPEDWTGFTMLWRDEDLDDIRGTSRA-W 374
            ....||.|.||..|..||..|.:|.|||:|||..:..:|.     ..|..|.:..:.|..... |
plant   302 TDAELFSPPLPDFKSDAIRRLGYGVVNKLFVEMSQRKFPS-----LQLVFDREDSEFRFVKIPWW 361

  Fly   375 LEDVFGFYRVSYQPRILAGWITNESGRHMETLPVDEVQAGVMYLFRRFLRWKIP-DPANFRT--- 435
            :........:....::|..|...:....:|.|..:|::..||.........::. |.|...|
plant   362 MRRTATITPIHSNSKVLLSWFAGKEALELEKLTDEEIKDAVMTTISCLTGKEVKNDTAKPLTNGS 426

  Fly   436 ---------------SAWYTNDNFRGSYSYRSMDTEQLGTGARELSHPLTVVATTPEKDKDSEDE 485
                           |.|.::..|||||||.::.:.  |.....::.||..:     ..|..:..
plant   427 LNDDDEAMKITKVLKSKWGSDPLFRGSYSYVAVGSS--GDDLDAMAEPLPKI-----NKKVGQVN 484

  Fly   486 AWQQSRCDRPIVQFAGEASSEHYYSTVHGAVEAGWREARRLAQFY 530
            ...|::.....|.|||||:...:|||.|||..:|.|||.||.:.|
plant   485 GHDQAKVHELQVMFAGEATHRTHYSTTHGAYYSGLREANRLLKHY 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7737	NP_001286308.1	NAD_binding_8	48..106	CDD:290186	26/64 (41%)
CG7737	NP_001286308.1	Amino_oxidase	54..526	CDD:279874	146/550 (27%)
PAO5	NP_194701.1	PLN02568	1..533	CDD:215308	155/565 (27%)
		NAD_binding_8	9..77	CDD:290186	28/72 (39%)
		NADB_Rossmann	<251..>288	CDD:304358	15/38 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	158	1.000	Domainoid score	I1289
eggNOG	1	0.900	-	-		E1_KOG0685
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	177	1.000	Inparanoid score	I1474
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D508351at2759
OrthoFinder	1	1.000	-	-		FOG0000632
OrthoInspector	1	1.000	-	-		otm3237
orthoMCL	1	0.900	-	-		OOG6_102123
Panther	1	1.100	-	-	O	PTHR10742
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X429
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.830