DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7737 and paox

DIOPT Version :9

Sequence 1:	NP_001286308.1	Gene:	CG7737 / 36174	FlyBaseID:	FBgn0033584	Length:	543	Species:	Drosophila melanogaster
Sequence 2:	NP_001314981.1	Gene:	paox / 562105	ZFINID:	ZDB-GENE-090312-204	Length:	510	Species:	Danio rerio

Alignment Length:	543	Identity:	168/543 - (30%)
Similarity:	240/543 - (44%)	Gaps:	75/543 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 SGAQR-NQDRKIVVIGAGASGVACATKLLELGFQNVLVVEAEDRLGGRIHTIPFADNVIDLGAQW 99
            |.||| ::|.:|.:||.|.||:..|.||::.||.||.::||..|.||||.|....||:|::||.|
Zfish     3 SMAQRPDRDSQIFIIGCGISGIGAAQKLIKHGFHNVRIIEATARSGGRIRTGRLGDNIIEIGANW 67

  Fly   100 CHG-ERDNIVYELTRKQDEELLESTGPVYENYEC-------------VRSNGDVVPEEVSSRLKA 150
            .|| .::|.|:.|.  .|.:||:......||...             ..|...:.||.:...|:.
Zfish    68 IHGPSKENPVFRLA--CDYQLLDKESMSEENQAIDIGGHPLFVPNWFTSSGRKLGPETMGPALEF 130

  Fly   151 IVGDSLVTRQLELRHCSG----SLGSYLTNKFYDTLRRPENSDIDAEVASEFFVN-YQKFENSVE 210
            .:  :|:.|..:.....|    |:|.::..:...........|.|........:| ..|.|..|.
Zfish   131 FM--TLLERSQQFHSTGGEPLPSVGEFIKAEAERLAPEEWKEDRDNFAVRMAMINTLLKLECCVS 193

  Fly   211 ASDTLEQVSGRGYLDYWECEG-DILLNWKDKGYVELLRLLMRSRELNVEHGVLEQRLLLGTRVVK 274
            .:.|::.|....:..|....| |...   ..||..|...:|:.         |.:.::|..:.||
Zfish   194 GTHTMDDVGLGAFGMYTTLPGLDCTF---PGGYEGLTDHMMKE---------LPRDIVLYNKPVK 246

  Fly   275 -INWN-----RNDG----RVELQMSNGETCIADHVVVTVSLGVLKDQHLRLFEPQLPVEKQRAID 329
             |:||     .|.|    .|.::..||||..||||:|||.||.:|........|..|:.|..:|.
Zfish   247 CIHWNYTKNGPNTGGTSFPVTIECVNGETFAADHVIVTVPLGYMKKHQNTFLSPSFPLHKLHSIQ 311

  Fly   330 GLAFGTVNKIFVEFPEAFWPEDWTGFTMLWRDED--LDDIRGTSRAWLEDVFGFYRVSYQPR--- 389
            .:.|||.|||||||.:.||.||.....::|.||.  .|.:.....:|:..:.||..:....|
Zfish   312 RMGFGTNNKIFVEFEQPFWDEDCELIYLVWEDETHLTDVVSDLKMSWIRKLTGFTVLKPTERFGH 376

  Fly   390 ILAGWITNESGRHMETLPVDEVQAGVMYLFRRFLRWKIPDPANFRTSAWYTNDNFRGSYSYRSMD 454
            :|.|||..:...:||:|...||...|..|.|.|.......|.....|.|:......|||||.:..
Zfish   377 VLCGWIAGQESEYMESLSELEVLQTVTQLLRIFTGNPTIMPRKLLRSQWFHEPYSCGSYSYVAKG 441

  Fly   455 TEQLGTGARELSHPLTVVATTPEKDKDSEDEAWQQSRCDRPI-VQFAGEASSEHYYSTVHGAVEA 518
            ..  |.....|:.||      |.|..:|           :|: |.|||||:...::||||||:.:
Zfish   442 CS--GYDIDNLAEPL------PLKGSNS-----------KPLQVLFAGEATHRSFFSTVHGALLS 487

  Fly   519 GWREARRLAQFYGISVSRSGTKS 541
            |||||.||...:   .|.||:.|
Zfish   488 GWREAERLISHH---TSASGSFS 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7737	NP_001286308.1	NAD_binding_8	48..106	CDD:290186	28/58 (48%)
CG7737	NP_001286308.1	Amino_oxidase	54..526	CDD:279874	153/507 (30%)
paox	NP_001314981.1	Amino_oxidase	26..503	CDD:332356	154/514 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583676
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0685
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D375579at33208
OrthoFinder	1	1.000	-	-		FOG0000632
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102123
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X429
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.650