DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7737 and shps

DIOPT Version :9

Sequence 1:	NP_001286308.1	Gene:	CG7737 / 36174	FlyBaseID:	FBgn0033584	Length:	543	Species:	Drosophila melanogaster
Sequence 2:	NP_651239.1	Gene:	shps / 42892	FlyBaseID:	FBgn0286199	Length:	477	Species:	Drosophila melanogaster

Alignment Length:	545	Identity:	96/545 - (17%)
Similarity:	173/545 - (31%)	Gaps:	216/545 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 IVVIGAGASGVACATKLLEL-GFQNVLVVEAEDRLGGRIHTIPFADNVIDLGAQWCHGERDNIVY 109
            ::::|.|.||:|.|.|:|.: ....|.::||.|.|||.:                  |:....:.
  Fly    14 VLIVGGGLSGLASALKILAMESTLKVRMIEASDALGGLM------------------GQNSTRLV 60

  Fly   110 ELTRKQDEELLESTGPVYENYECVRSNGDVVPEEVSSRLKAIVGDSL-----VTRQLELRHCSGS 169
            :..::....||...                   .:|.|.:..:..||     :.|.|........
  Fly    61 DAAQQDMLALLTLI-------------------HLSPRRRRSISGSLRRCWDLDRGLTAMPAKFE 106

  Fly   170 LGSYL----------TNKFYDTLRRPENSD------IDAEVASEFFVNYQKFENSVEASDTLEQV 218
            ||.|:          .:|.::...|..|.:      :....:..|.:|..:....|.|::
  Fly   107 LGRYIDMLDLRMPKFRSKRFNLRERVSNMEQHICHHLFFSKSRNFMLNLVQLVCGVPANE----- 166

  Fly   219 SGRGYLDY-------WECEG-DILLNW---KDKGYVELLRLLMRSRELNVEHGVLEQ----RLLL 268
                 :||       ..|.| .:|:::   ....:.|:      |.::.:|: :|||    :::|
  Fly   167 -----VDYDVFMSVCSSCGGLKVLIDFYFTYPTSFYEI------STQMLIEN-ILEQLQFIKIIL 219

  Fly   269 GTRVVKINWNRNDGRVELQMSNGETCIADHVVVTVSLGVLKDQHLRLFEPQLPVEKQRAIDGLAF 333
            ..|.|::...:|..:|.....|..|  |...::.:....::..|   |||::|
  Fly   220 NCRAVRLEHFKNYVQVTDDQGNKHT--AQAAILAIPWNKVQKLH---FEPRIP------------ 267

  Fly   334 GTVNKIFV----------------EFPEAFWPEDWTGFTMLWRDEDLDDIRGTSRAWLEDVFGFY 382
                |:|:                :|...:....||         ||    |.|..:|
  Fly   268 ----KVFLPRTTSRSGRKGRQVISQFQLRYGKSVWT---------DL----GYSGNFL------- 308

  Fly   383 RVSYQPRI---------LAGWITNESGRHMETLP--VDEVQAGVMYLFRRFLRWKIPDPANFRTS 436
              |.||.:         ..|::.:        ||  .|||...|:.|.
  Fly   309 --SSQPMVSGHECRMSSFCGYVLH--------LPEDQDEVLQDVVDLL----------------- 346

  Fly   437 AWYTNDNFRGSYSYRSMDTEQLGTGARELSHPLTVVATTPE---KDKDSEDEAWQQSRCDRPIVQ 498
                              .|..|   .|:..||.....|.|   .....:.:.|.:      ::.
  Fly   347 ------------------AEHFG---EEMRQPLECQCFTDELNVAQHKPQTKPWHR------VIW 384

  Fly   499 FAGEASSEHYYSTVHGAVEAGWREA 523
            .:..|....|.|.:.|||::|:|.|
  Fly   385 SSSSAVGTSYRSLMGGAVQSGFRAA 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7737	NP_001286308.1	NAD_binding_8	48..106	CDD:290186	16/58 (28%)
CG7737	NP_001286308.1	Amino_oxidase	54..526	CDD:279874	94/537 (18%)
shps	NP_651239.1	NADB_Rossmann	11..>53	CDD:304358	15/56 (27%)
shps	NP_651239.1	Amino_oxidase	21..409	CDD:279874	93/536 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452794
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840