Protein Alignment CG7737 and MAOB

DIOPT Version :10

• Sequence 1: NP_001286308.1
• Gene: CG7737 / 36174
• FlyBaseID: FBgn0033584
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_000889.3
• Gene: MAOB / 4129
• HGNCID: 6834
• Length: 520
• Species: Homo sapiens
• Alignment Length: 542
• Identity: 128/542 - (23%)
• Similarity: 202/542 - (37%)
• Gaps: 149/542 - (27%)

  Fly    46 IVVIGAGASGVACATKLLELGFQNVLVVEAEDRLGGRIHTIPFAD-NVIDLGAQWCHGERDNIVY 109
            :||:|.|.||:| |.|||.....||:|:||.||:|||.:|:.... ..:|||..:. |...|.:.
Human     7 VVVVGGGISGMA-AAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYV-GPTQNRIL 69

  Fly   110 ELTRKQDEELLESTGPVYENYECVRSNGDVVPEEVSSRLKAIVGDSLVTRQLELRHCSGSLG--- 171
            .|.::..          .|.|:.         .||...:..:.|.|...|        |...
Human    70 RLAKELG----------LETYKV---------NEVERLIHHVKGKSYPFR--------GPFPPVW 107

  Fly   172 ---SYLT-NKFYDTL-----RRPENSDIDAEVASEFFVNYQK------------------FENSV 209
               :||. |.|:.|:     ..|.::...|.:|.|:.....|                  |.|..
Human   108 NPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLC 172

  Fly   210 EASDTLEQVSGRGYLDY-WECEGDILLNWKDKGYVELLRLLMRSRELNVEHGVLEQRL--LLGTR 271
            ..::| .:||...:|.| .:|.|...:.....|..|        |:.....|.:.:|:  |||.|
Human   173 VTAET-HEVSALWFLWYVKQCGGTTRIISTTNGGQE--------RKFVGGSGQVSERIMDLLGDR 228

  Fly   272 ------VVKINWNRNDGRVELQMSNGETCIADHVVVTV--SLGVLKDQHLRL-FEPQLPVEKQRA 327
                  |:.|:..|.:  |.::..|.|...|.:|:..:  :||      ::: |.|.||:.:.:.
Human   229 VKLERPVIYIDQTREN--VLVETLNHEMYEAKYVISAIPPTLG------MKIHFNPPLPMMRNQM 285

  Fly   328 IDGLAFGTVNKIFVEFPEAFW-PEDWTGFTMLWRDED------LDDIRGTSRAWLEDVFGFYRVS 385
            |..:..|:|.|..|.:.|.|| .:|:.| ||:...|:      |||.:..         |.|..
Human   286 ITRVPLGSVIKCIVYYKEPFWRKKDYCG-TMIIDGEEAPVAYTLDDTKPE---------GNYAA- 339

  Fly   386 YQPRILAGWITNESGRHMETLPVDEVQAGVMYLFRRFL-RWKIPDPANFRTSAWYTNDNFRGSYS 449
                 :.|:|.....|.:..|..:|....:..|:.:.| ..:..:|.::....|.......|.|
Human   340 -----IMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCY- 398

  Fly   450 YRSMDTEQLGTG-----ARELSHPLTVVATTPEKDKDSEDEAWQQSRCDRPIVQFAGEASSEHYY 509
                 |.....|     .|.|..|:                       ||  :.|||..::.|:.
Human   399 -----TTYFPPGILTQYGRVLRQPV-----------------------DR--IYFAGTETATHWS 433

  Fly   510 STVHGAVEAGWREARRLAQFYG 531
            ..:.||||||.|.||.:....|
Human   434 GYMEGAVEAGERAAREILHAMG 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7737	NP_001286308.1	Amino_oxidase	54..526	CDD:396255	123/527 (23%)
MAOB	NP_000889.3	YobN	14..455	CDD:440844	123/533 (23%)