Protein Alignment CG7737 and MAOA

DIOPT Version :9

• Sequence 1: NP_001286308.1
• Gene: CG7737 / 36174
• FlyBaseID: FBgn0033584
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_000231.1
• Gene: MAOA / 4128
• HGNCID: 6833
• Length: 527
• Species: Homo sapiens
• Alignment Length: 570
• Identity: 125/570 - (21%)
• Similarity: 205/570 - (35%)
• Gaps: 187/570 - (32%)

  Fly    41 NQDR--------KIVVIGAGASGVACATKLLELGFQNVLVVEAEDRLGGRIHTIPFAD-NVIDLG 96
            ||::        .:||||.|.||::.|..|.|.|. :|||:||.||:|||.:||.... :.:|:|
Human     3 NQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGV-SVLVLEARDRVGGRTYTIRNEHVDYVDVG 66

  Fly    97 AQWCHGERDNIVYELTRK---------QDEELLEST---------------GPV----YEN-YEC 132
            ..:. |...|.:..|:::         ..|.|::..               .|:    |.| :..
Human    67 GAYV-GPTQNRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGAFPPVWNPIAYLDYNNLWRT 130

  Fly   133 VRSNGDVVPEEVSSRLK-AIVGDSLVTRQLELRHCSGSLGSYLTNKFYDTLRRPENSDIDAEVAS 196
            :.:.|..:|.:.....: |...|.:..::|..:.|           :..|.||          .:
Human   131 IDNMGKEIPTDAPWEAQHADKWDKMTMKELIDKIC-----------WTKTARR----------FA 174

  Fly   197 EFFVNYQKFENSVEASDTLEQVSGRGYLDY-WECEGDILLNWKDKGYVELLRLLMRSRELNVEHG 260
            ..|||       :..:....:||...:|.| .:|.|...:.....|..|        |:.....|
Human   175 YLFVN-------INVTSEPHEVSALWFLWYVKQCGGTTRIFSVTNGGQE--------RKFVGGSG 224

  Fly   261 VLEQRL--LLGTRVVKINW-----NRNDGRVELQMSNGETCIADHVVVTVSLGVLKDQHLRLFEP 318
            .:.:|:  |||.: ||:|.     :::...:.::..|.|.....:|:..:...:....|   |.|
Human   225 QVSERIMDLLGDQ-VKLNHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIH---FRP 285

  Fly   319 QLPVEKQRAIDGLAFGTVNKIFVEFPEAFW-PEDWTGFTMLWRDED------LDDIRGTSRAWLE 376
            :||.|:.:.|..|..|.|.|..:.:.|||| .:|:.| .|:..|||      |||.:....  |.
Human   286 ELPAERNQLIQRLPMGAVIKCMMYYKEAFWKKKDYCG-CMIIEDEDAPISITLDDTKPDGS--LP 347

  Fly   377 DVFGFYRVSYQPRILAGWITNESGRHME--TLPVDEVQAGVMYLFRRFLRWKIPDPANFRTSAWY 439
            .:.||        |||......:..|.|  ...:.|:.|.|:
Human   348 AIMGF--------ILARKADRLAKLHKEIRKKKICELYAKVL----------------------- 381

  Fly   440 TNDNFRGSYSYRSMDTEQLGTGARELSHPLTVVATTPEKDKDSEDEAW----------------- 487
                                 |::|..||:           ..|::.|
Human   382 ---------------------GSQEALHPV-----------HYEEKNWCEEQYSGGCYTAYFPPG 414

  Fly   488 ---QQSRCDR-PI--VQFAGEASSEHYYSTVHGAVEAGWREARRLAQFYG 531
               |..|..| |:  :.|||..::..:...:.||||||.|.||.:....|
Human   415 IMTQYGRVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLG 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7737	NP_001286308.1	NAD_binding_8	48..106	CDD:290186	25/58 (43%)
		Amino_oxidase	54..526	CDD:279874	117/542 (22%)
MAOA	NP_000231.1	YobN	15..460	CDD:224152	122/552 (22%)
		Interaction with membrane phospholipid headgroups. /evidence=ECO:0000305	520..522

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149524
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840