DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7737 and CG8032

DIOPT Version :9

Sequence 1:	NP_001286308.1	Gene:	CG7737 / 36174	FlyBaseID:	FBgn0033584	Length:	543	Species:	Drosophila melanogaster
Sequence 2:	NP_001262380.1	Gene:	CG8032 / 41026	FlyBaseID:	FBgn0037606	Length:	583	Species:	Drosophila melanogaster

Alignment Length:	611	Identity:	153/611 - (25%)
Similarity:	240/611 - (39%)	Gaps:	203/611 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 PGMSGAQRNQDRKIVVIGAGASGVACATKLLELGFQNVLVVEAEDRLGGRIHTIPFADN-VIDLG 96
            |..||  .|.:.|||:||||.:|::.|..||:.|..:.|::||..|:||||.:||.::| .|:||
  Fly    31 PQTSG--NNTNVKIVIIGAGMAGLSAANHLLQNGCDDFLILEARGRVGGRIVSIPLSNNQKIELG 93

  Fly    97 AQWCHGERDNIVYELTRK----------QDEELLEST-----------GPVYENYEC-------- 132
            |.|.||...|.::||..:          :..:::.:|           ..:||.|.|
  Fly    94 ANWIHGVLGNPIFELAVQHGLVSVVNVPKPHKVVATTEDGHQVPFNILQEIYEAYVCFLRRCDEY 158

  Fly   133 ----------VRSNGDVVPEEV-----------SSRLKAIVGDSLVTRQLELRHCSGSLGSYLTN 176
                      :.|.|:.:..|:           ..|||..:.:.|:.|:..:..|
  Fly   159 FLCQYSPPPDIHSVGEHINYEIEIYLSGVQDPKEKRLKQSIFNCLLKRETCITGC---------- 213

  Fly   177 KFYDTLRRPENSDIDAEVASEFFVNYQKFENSVEASDTLEQVSGRGYLDYWECE-GDILLNWKDK 240
                                          |:::..|.||..|      |.|.: |:|:|   ..
  Fly   214 ------------------------------NNMDEVDLLELGS------YTELQGGNIVL---PT 239

  Fly   241 GYVELLRLLMRSRELNVEHGVLEQRLLLGTRVVKINWNRND------------------------ 281
            ||..:||.|...        :.:|.:|....|.||:|.|..
  Fly   240 GYSSILRPLGAQ--------IAKQSILTKCPVKKIHWKRKKTFTGLETVDENSEDEHSDDSERTV 296

  Fly   282 -------------------------GRVELQMSNGETCIADHVVVTVSLGVLKDQHLRLFEPQLP 321
                                     |.|.:...:|....|.||:.|:.|||||:.|..||:|.||
  Fly   297 TEVPTGEIRGASVESNTSSNCDYPAGNVRIDCEDGRVFHAAHVICTIPLGVLKNTHRTLFDPVLP 361

  Fly   322 VEKQRAIDGLAFGTVNKIFVEFPEAFWPEDWTGFTMLWRDEDLDDIRGT----------SRAWLE 376
            ..||.:|:.|.||||:|||:|:...|...|.:...:|| |:|..|:..:          |:.|.:
  Fly   362 QYKQESIENLMFGTVDKIFLEYERPFLSADISEIMLLW-DDDKRDMNSSEEELASEAYLSKNWFK 425

  Fly   377 DVFGFYRVSYQPRILAGWITNESGRHMETLPVDEVQAGVMYLFRRFLRWK-IPDPANFRTSAWYT 440
            .::.|.:|:  ..:|.||::.....:||.|..:.|......:.|.||:.. :|.|.....::|.:
  Fly   426 KIYSFAKVT--DTLLLGWVSGREAEYMEKLDHEAVAEKCTEILRNFLQDPYVPKPKRCVCTSWKS 488

  Fly   441 NDNFRGSYSYRSMDTEQLGTGARE-----LSHPLTVVATTPEKDKDSEDEAWQQSRCDRPIVQFA 500
            .|...|:|:       .:..||.:     |:.||   ..||:..|              |.:.||
  Fly   489 QDFTGGAYT-------SIPVGATQEDIENLAQPL---YATPQAMK--------------PAIVFA 529

  Fly   501 GEASSEHYYSTVHGAVEAGWREARRL 526
            ||.:...:|||||||..:|...|:.|
  Fly   530 GEHTHSSFYSTVHGAYLSGRTAAQHL 555

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7737	NP_001286308.1	NAD_binding_8	48..106	CDD:290186	27/58 (47%)
CG7737	NP_001286308.1	Amino_oxidase	54..526	CDD:279874	141/588 (24%)
CG8032	NP_001262380.1	NAD_binding_8	44..104	CDD:290186	27/59 (46%)
CG8032	NP_001262380.1	Amino_oxidase	49..556	CDD:279874	142/591 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452805
Domainoid	1	1.000	122	1.000	Domainoid score	I1237
eggNOG	1	0.900	-	-		E1_KOG0685
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D375579at33208
OrthoFinder	1	1.000	-	-		FOG0000632
OrthoInspector	1	1.000	-	-		otm46708
orthoMCL	1	0.900	-	-		OOG6_102123
Panther	1	1.100	-	-	P	PTHR10742
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X429
	10	9.750